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Abnormal Liver Tests

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Liver Disease

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Abstract

The burden of chronic liver disease continues to increase in the United States. While there have been major achievements in the treatment of certain chronic liver diseases including chronic viral hepatitis, practicing clinicians routinely encounter patients with elevated liver tests. It is important for clinicians to be able to recognize liver tests that are outside the normal range and proceed with a focused evaluation that is tailored to the clinical presentation.

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Further Reading

  1. Kwo PY, Cohen SM, Lim JK. ACG clinical guideline: evaluation of abnormal liver chemistries. Am J Gastroenterol. 2017;112:18–35.

    Article  CAS  Google Scholar 

  2. Udompap P, Kim D, Kim WR. Current and future burden of chronic nonmalignant liver disease. Clin Gastroenterol Hepatol. 2015;13:2031–41.

    Article  Google Scholar 

  3. Chalasani N, et al. The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases. Hepatology. 2018;67:328–57.

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  4. CDC guidelines on HCV screening. https://www.cdc.gov/hepatitis/hcv/guidelinesc.htm. Accessed 30 May 2018

  5. AASLD/IDSA Recommendations for Testing, Managing, and Treating Hepatitis C. 2015. http://www.hcvguidelines.org/full-report-view. Accessed 2 Mar 2015.

  6. Dutta A, Saha C, Johnson CS, et al. Variability in the upper limit of normal for serum alanine aminotransferase levels: a statewide study. Hepatology. 2009;50:1957–62.

    Article  CAS  Google Scholar 

  7. Ruhl CE, Everhart JE. Elevated serum alanine aminotransferase and gamma-glutamyltransferase and mortality in the United States population. Gastroenterology. 2009;136:477–85.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Stanford University School of Medicine, Palo Alto, CA, USA

    Paul Y. Kwo & Katherine Wong

Authors
  1. Paul Y. Kwo
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  2. Katherine Wong
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Correspondence to Paul Y. Kwo .

Editor information

Editors and Affiliations

  1. Case Western Reserve University, School of Medicine, University Hospitals of Cleveland, Cleveland, OH, USA

    Stanley Martin Cohen

  2. Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH, USA

    Perica Davitkov

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© 2019 Springer Nature Switzerland AG

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Cite this chapter

Kwo, P.Y., Wong, K. (2019). Abnormal Liver Tests. In: Cohen, S., Davitkov, P. (eds) Liver Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-98506-0_12

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  • DOI: https://doi.org/10.1007/978-3-319-98506-0_12

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-98505-3

  • Online ISBN: 978-3-319-98506-0

  • eBook Packages: MedicineMedicine (R0)

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