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Epithelium-On Corneal Cross-Linking

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Controversies in the Management of Keratoconus

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Abstract

This chapter reviews the published literature on epithelium-on (trans-epithelial) Riboflavin and Ultraviolet A (UVA) 370 nanometre (nm) light corneal collagen cross-linking (TE-CXL). Importance has been placed on seminal publications, systemic reviews, meta-analyses and randomized controlled clinical trials. Where such evidence was not available, cohort studies, case controlled studies and case series with follow-up greater than 12 months were examined.

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Financial Disclosures Related to Manuscript

Professor O’Brart holds non-commercial research grants from Alcon Inc. and Avedro Inc.

He has undertaken paid consultancy work for Alcon Inc. and Sooft Italia SPA in the past 12 months

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  1. King’s College, London and Guy’s and St. Thomas’ NHS Foundation Trust, Department of Ophthalmology, St. Thomas’ Hospital, London, UK

    David P. S. O’Brart

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  1. Medical Director of IVISION, Refractive Surgery and Keratoconus Treatment Center, Haifa, Israel

    Adel Barbara

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O’Brart, D.P.S. (2019). Epithelium-On Corneal Cross-Linking. In: Barbara, A. (eds) Controversies in the Management of Keratoconus . Springer, Cham. https://doi.org/10.1007/978-3-319-98032-4_5

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