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The Mediastinal Mass pp 65–127Cite as

Diagnostic Histopathology Approach

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Part of the book series: Current Clinical Pathology ((CCPATH))

Abstract

The mediastinum is a complex thoracic region containing numerous vital structures of different cell differentiation (ectoderm, mesoderm, and endoderm) and possibly generating benign and malignant lesions leading to life-threatening conditions. Facing with mediastinal masses often represents a diagnostic challenge for generalist pathologist. A morphology-based approach consisting of six main pattern recognitions, namely, (1) epithelioid cell, (2) spindle cell, (3) small-cell, (4) clear-cell, (5) fibroinflammatory-looking, and(6) cystic patterns, is here proposed as a practical approach to mediastinal masses.

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Authors and Affiliations

  1. Operative Unit of Pathologic Anatomy, Azienda della Romagna, Hospital S. Maria delle Croci, Ravenna, Italy

    Giulio Rossi

  2. Unit of Pathology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy

    Moira Ragazzi & Alberto Cavazza

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  1. Giulio Rossi
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  2. Moira Ragazzi
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  3. Alberto Cavazza
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  1. Pathology Unit, Department of Mental and Physic Health and Preventive Medicine, Università della Campania ‘Luigi Vanvitelli’, Naples, Italy

    Renato Franco

  2. Pathology Unit, Department of Mental and Physic Health and Preventive Medicine, Università della Campania ‘Luigi Vanvitelli’, Naples, Italy

    Federica Zito Marino

  3. Sbarro Institute for Cancer Research, Temple University Sbarro Institute for Cancer Research, Philadelphia, PA, USA

    Antonio Giordano

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Rossi, G., Ragazzi, M., Cavazza, A. (2018). Diagnostic Histopathology Approach. In: Franco, R., Zito Marino, F., Giordano, A. (eds) The Mediastinal Mass. Current Clinical Pathology. Humana, Cham. https://doi.org/10.1007/978-3-319-90368-2_6

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