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Physical Health and Clinical Phenotypes

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Book cover Physical Health of Adults with Intellectual and Developmental Disabilities

Abstract

This chapter is devoted to the physical health issues associated specifically with intellectual disability caused by genetic syndromes. The first part of the chapter will describe certain key genetic concepts. This will be followed by a tabulation of major specific disorders which are referenced throughout the chapter. This table will summarize the disorders in terms of genetic cause, approximate incidence, level of intellectual disability and major phenotypic characteristics. Following a brief overview of the morbidity and mortality associated with intellectual disability various clinical presentations of these disorders will be examined system by system. These will include cardiovascular, respiratory, gastrointestinal, endocrine and neurological problems. Aside from detailing the most common clinical presentations the chapter will also outline prevention and management strategies which should be kept in mind for this patient group.

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Author information

Authors and Affiliations

  1. Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK

    Andre Strydom

  2. Maudsley Hospital, London, UK

    Alexander Curmi

  3. Molecular Psychiatry Laboratory, Division of Psychiatry, UCL, London, UK

    Andrew McQuillin

Authors
  1. Andre Strydom
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  2. Alexander Curmi
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  3. Andrew McQuillin
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Corresponding author

Correspondence to Andre Strydom .

Editor information

Editors and Affiliations

  1. The Greenfields, Birmingham, UK

    Vee P. Prasher

  2. University of Illinois at Chicago, Chicago, IL, USA

    Matthew P. Janicki

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Strydom, A., Curmi, A., McQuillin, A. (2019). Physical Health and Clinical Phenotypes. In: Prasher, V., Janicki, M. (eds) Physical Health of Adults with Intellectual and Developmental Disabilities. Springer, Cham. https://doi.org/10.1007/978-3-319-90083-4_5

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  • DOI: https://doi.org/10.1007/978-3-319-90083-4_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-90082-7

  • Online ISBN: 978-3-319-90083-4

  • eBook Packages: MedicineMedicine (R0)

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