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Effects of Sleep Deprivation and Experience on Sleep Characteristics and Memory Formation Based on EEG Analysis

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Handbook of Computational Neurodegeneration

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Abstract

Sleep is believed to play an important role in cognitive functions. The underlying mechanisms of the relationship between the effects of waking experiences (i.e., sleep deprivation [SD] and enriched environment [EE]) on sleep characteristics (sleep states and brain waves) are believed to be beneficial. Sleep is divided into two main stages: non-rapid eye movement (non-REM) and REM sleep. Electroencephalogram (EEG) in adult mice was used in order to record and compare changes in sleep stages and specific brain waves (i.e., oscillations) during sleep following those waking experiences. Results showed that both waking experiences significantly increase NREM sleep amount and duration. However, SD and EE differentially affect slow wave activity (SWA: 0.5–4.0 Hz) and spindle-rich sigma activity (9–16 Hz), the two main sleep oscillations of NREM sleep. The conclusions were that extended wakefulness (i.e., SD) and learning (i.e., EE) differentially affect NREM EEG signatures (SWA, spindles). The obtained results support previous data which shows that these oscillations are important for cognition and further suggest that their differential regulation by experiences may account for different functions.

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Author information

Authors and Affiliations

  1. Bioinformatics and Human Electrophysiology Laboratory, Department of Informatics, Ionian University, Corfu, Greece

    Konstantina Skolariki

  2. Surrey Sleep Research Centre, University of Surrey, Guildford, UK

    Konstantina Skolariki & Julie Seibt

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  1. Konstantina Skolariki
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  2. Julie Seibt
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Editors and Affiliations

  1. Department of Informatics, Ionian University, Corfu, Greece

    Panagiotis Vlamos

  2. Wilfrid Laurier University, Waterloo, ON, Canada

    Ilias S. Kotsireas

  3. Altoida Inc, Atlantic Fellow with the Global Brain Health Institute, Trinity College Dublin, Dublin, Ireland

    Ioannis Tarnanas

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Skolariki, K., Seibt, J. (2023). Effects of Sleep Deprivation and Experience on Sleep Characteristics and Memory Formation Based on EEG Analysis. In: Vlamos, P., Kotsireas, I.S., Tarnanas, I. (eds) Handbook of Computational Neurodegeneration. Springer, Cham. https://doi.org/10.1007/978-3-319-75922-7_56

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