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Brain Estrogens and Feeding Behavior

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Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1043))

Abstract

Estrogens play essential roles in suppressing food intake and preventing body weight gain. Tremendous research efforts have been focused on estrogen physiology in the context of feeding control. Estrogen receptors and the related signals have been attractive targets for development of new obesity therapies. This chapter focuses on the functional interactions between brain estrogens and other appetite-regulatory signals, the critical estrogen receptor isoforms and distinct brain regions that mediate effects of estrogens on feeding, and the intracellular signals that are involved.

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  1. USDA/ARS Children’s Nutrition Research Center, Department of Pediatrics, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA

    Yong Xu

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  1. Department of Medicine, Section of Endocrinology and Metabolism, Tulane University Health Sciences Center, School of Medicine, New Orleans, Louisiana, USA

    Franck Mauvais-Jarvis

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Xu, Y. (2017). Brain Estrogens and Feeding Behavior. In: Mauvais-Jarvis, F. (eds) Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity. Advances in Experimental Medicine and Biology, vol 1043. Springer, Cham. https://doi.org/10.1007/978-3-319-70178-3_16

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