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Metal Nanoparticles in Pharma pp 389–415Cite as

Nanometals in Bhasma: Ayurvedic Medicine

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Abstract

Bhasmas are unique Ayurvedic metallic preparations with herbal juices or fruits, known in the Indian subcontinent since the seventh century BC and widely recommended for treatment of a variety of chronic ailments. More than 18 Bhasmas based on calcium, iron, zinc, mercury, silver, potassium, arsenic, copper, tin, and gemstones were analyzed for up to 18 elements by instrumental neutron activation analysis method, including their C, H, N, and S contents. In addition to the major constituent elements found at percent level, several other essential elements such as Na, K, Ca, Mg, V, Mn, Fe, Cu, and Zn have also been found in μg/g amounts and ultratrace (ng/g) amounts of Au and Co. The Bhasmas are biologically produced nanoparticles and are taken along with milk, butter, honey, or ghee thus; this makes these elements easily assimilable, eliminating their harmful effects and enhancing their biocompatibility. Particle size (1–2 μm) is reduced significantly, which may assist absorption and assimilation of the drug into the body system. Standardization of Bhasma is utmost necessary to confirm its identity and to determine its quality, purity safety, effectiveness, and suitability of the product. But the most important challenges faced by these formulations are the lack of complete standardization by physiochemical parameters.

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Abbreviations

AFM:

Atomic Force Microscopy

Ag:

Silver

Au:

Gold

CaO:

Calcium Oxide

DLS:

Dynamic Light Scattering

EDAX:

Elemental Analysis with Energy Dispersive X-Ray Analysis

GIT:

Gastro-Intestinal Tract

ICP:

Inductively Coupled Plasma

NIH:

National Institute of Health

NPs:

Nanoparticles

PbS:

Lead Suilphide

PXRD:

Powder X-Ray Diffraction

TEM:

Transmission Electron Microscopy

XPS:

X-ray Photoelectron Spectroscopy

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Authors and Affiliations

  1. Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Koni, Bilaspur, 495 009, Chhattisgarh, India

    Dilipkumar Pal & Vinod Kumar Gurjar

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  1. Dilipkumar Pal
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  2. Vinod Kumar Gurjar
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Correspondence to Dilipkumar Pal .

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Editors and Affiliations

  1. Nanobiotechnology laboratory, Department of Biotechnology, SGB Amravati University, Amravati, Maharashtra, India

    Mahendra Rai, Ph.D

  2. Institute of Pharmacy, Department Pharmaceutics, Biopharmaceutics & NutriCosmetics, Freie Universität Berlin, Berlin, Germany

    Ranjita Shegokar, Ph.D

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Pal, D., Gurjar, V.K. (2017). Nanometals in Bhasma: Ayurvedic Medicine. In: Rai, Ph.D, M., Shegokar, Ph.D, R. (eds) Metal Nanoparticles in Pharma. Springer, Cham. https://doi.org/10.1007/978-3-319-63790-7_17

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