Abstract
Prostate cancer is truly an ancient disease with a fascinating history that was locally aggressive during the mid-to-late nineteenth century when awareness of this illness began to accrue. With the foundations of the specialty of urology, locally aggressive radical surgeries were tried in the early twentieth century with relatively poor outcomes. Only when the marker, prostate specific antigen (PSA) became available did the perfect storm arise—early detection, early treatment and rapid surgical changes. But radiation therapy also became an effective treatment alternative, beginning first with brachytherapy methods, followed by what James M. Slater has classically referred to as the four major eras of radiation therapy—the era of discovery, the orthovoltage era, the megavoltage era and finally the intensity-modulated era which is still ongoing [1]. Into this realm the proton accelerator (ion beam therapies with protons just being one) must also be factored as well as combined radiation modalities—or the high dose regimens and radiopharmaceuticals.
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References
Brodie BC. Lectures on the diseases of the urinary organs. Philadelphia: Lea & Blanchard; 1847.
Breasted JH. The Edwin Smith surgical papyrus: hieroglyphic transliterations, translations and commentary. Chicago: University of Chicago Press; 1930.
Bermejo C, Kristal AR, Zeliadt SB, Ramsey S, Thompson IM. Localized prostate cancer: quality of life meets Whitmore’s legacy. J Natl Cancer Inst. 2004;96(18):1348–9.
Marks MK, Hamilton MD. Metastatic carcinoma: palaeopathology and differential diagnosis. Int J Osteoarchaeology. 2007;17:217–34.
Johnson G. The cancer chronicles: unlocking medicine deepest mystery. New York: Alfred A. Knopf; 2013.
Schultz M, Parzinger H, Posdnjakov DV, Chikisheva TA, Schmidt-Shultz TH. Oldest known case of metastasizing prostate carcinoma diagnosed in the skeleton of a 2,700 year-old Scythian King from Arzhan (Siberia, Russia). Int J Cancer. 2007;121:2591–5.
Baillie M. The morbid anatomy of some of the most important parts of the human body. London: J. Johnson; 1793.
Walshe WH. The nature and treatment of cancer. London: Taylor & Walton; 1846.
Adams J. The diseases of the prostate, their pathology and treatment. London: Longman, Brown, Green & Longmans; 1851.
Thompson H. The diseases of the prostate their pathology and treatment comprising the Jacksonian Prize essay for the year 1860. 5th ed. London: J & A Churchill; 1883.
Harrison R. Remarks on cancer of the prostate and the selection of cases for suprapubic prostatectomy. BMJ. 1903;2:1.
Von Recklinghausen FD. Die fibrose und deformirende Ostititis der Osteomalacie und die osteoplastichen Carcinome in ihren gegenseitigen Beziehungen. Festschr Z Virchow. 1891;1:89–93.
Sasse F. Ostitis carcinomatose bei Carcinom der Prostata. Arch Klin Chir. 1894;48:596–8.
Pasteau O. Itat du systome lymphatique dans les maladies de la vessie et de la prostate. Those de la Facult de Med de Paris 1898;107.
Blumer G. A report of two cases of osteoplastic carcinoma of the prostate with a review of the literature. Johns Hopkins Hosp Bull. 1909;20:200–4.
Hunter J. Observations on certain parts of the animal oeconomy. London: Bibliotecha Osteriana; 1786. p. 28–9.
White WJ. The results of double castration in the hypertrophy of the prostate. Ann Surg. 1895;22:1–3.
Demming CL, Jenkins RH, Van Wagenen G. Further studies in the endocrinological relationship of prostatic hypertrophy. J Urol. 1935;34:678–85.
Moore RA, McClellan AM. Histological study of the effect of the sex hormones on the human prostate. J Urol. 1938;40:641–57.
Hansson N, Moll F, Schultheiss D, Krischel M. Remembering Charles B. Huggins’ Nobel Prize for hormonal treatment of prostatic cancer at its 50th anniversary. Eur Urol. 2016;69(6):971–2.
Huggins CB, Clark PJ. Quantitative studies of prostatic secretion. II. The effect of castration and estrogen injection on the hyperplastic prostate glands of dogs. J Exp Med. 1940;72:747.
Huggins CB, Stevens RA. The effect of castration on benign hypertrophy of the prostate in man. J Urol. 1940;43:105.
Huggins CB, Hodges CV. Studies on prostate cancer. I. The effects of castration, of estrogen and androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res. 1941;1:203.
Veterans Administration Cooperative Urological Research Group. Treatment and survival of patients with cancer of the prostate. Surg Gynecol Obstet. 1967;124:1011–7.
Schally AV, Kastin AJ, Arimura A. Hypothalamic FSH and LH-regulating hormone. Structure, physiology and clinical studies. Fertil Steril. 1971;22:703–21.
Schally AV, Kastin AJ, Coy DHLH. Releasing hormone and its analogues. In J Fertil. 1976;1:1–5.
Denmeade SR, Isaacs JT. A history of prostate cancer treatment. Nat Rev Cancer. 2002;2(5):389–96.
Billroth T. Chirurgishce Erfahrungen in Zurich 1860-1867. Langenbecks Arch Klin Chir. 1869;10:547–54.
Androutsos G. Carcinoma of the prostate. A historical account. J BUON. 2005;10:135–44.
Young HH. The early diagnosis and radical cure of carcinoma of the prostate. Bull Johns Hopkins. 1905;16(175):315–21.
Colston JAC. Carcinoma of the prostate: a study of the percentage of cases suitable for the radical operation. JAMA. 1943;122(12):781–4.
Deaver JB. Surgery of the prostate gland. Am J Med Sci. 1904:1–39.
Walsh PC. The discovery of the cavernous nerves and development of nerve sparing radical retropubic prostatectomy. J Urol. 2007;177(5):1632–5.
Moran ME. The history of robotic surgery. In: Hemal AK, Menon M, editors. Robotics in genitourinary surgery. New York: Springer; 2011.
Dronsfield A, Ellis P. Radium-a key element in early cancer treatment. Educ Chem. 2011;3:56–9.
Tesla N. An interesting feature of X-ray radiations. Elect Rev N Y. 1896;29(2):13–4.
Bergonié J, Tribondeau L. Interpretation de quelques resultants de la radiothérapie et essai de fixation d’unde technique rationelle. Compt Red Acad Sci. 1906;143:983–5.
Silverstone SM. Robert Abbe: founder of radium therapy in America. Bull N Y Acad Med. 1956;32(2):157–67.
Abbe R. On what lines is the treatment of malignant disease advancing? Med Rec. 1904;66:1041–3.
Goldsmith B. Obsessive genius: the inner world of Marie Curie. New York: W.W. Norton; 2005.
Welsome E. The plutonium files: America’s secret medical experiments in the cold war. New York: The Dial Press; 1999.
Slater JM. From X-rays to ion beams: a short history of radiation therapy. In: Linz U, editor. Ion beam therapy, biological and medical physics, biomedical engineering. New York: Springer; 2012.
Oslson JS. Making of cancer history: disease & discovery at the University of Texas M.D. Anderson Cancer Center. Baltimore: Johns Hopkins University Press; 2009.
Barringer B. Radium in the treatment of carcinoma of the bladder and prostate: review of one year’s work. JAMA. 1917;68:1227–30.
Rosevear HM, Lightfoot AJ, O’Donnell MA, Platz CE, Loening SA, Hawtrey CE, Rubin H. Flocks and colloidal gold treatments for prostate cancer. Sci World J. 2011;11:1560–7.
Bagshaw MA, Ray GR, Cox RS. Selecting initial therapy for prostate cancer: radiation therapy perspective. Cancer. 1987;60:521–5.
Van Dyk J, Battista JJ, Bauman GS. Accuracy and uncertainty considerations in modern radiation oncology. In: The modern technology of radiation oncology. Madison: Modern Physics Publishing; 1999.
Stone RS, Lawrence JH, Aebersold PD. A preliminary report on the use of fast neutrons in the treatment of malignant disease. Radiology. 1940;37:322–7.
Body JJ, Casimiro S, Costa L. Targeting bone metastases in prostate cancer: improving clinical outcome. Nat Rev Urol. 2015;12:340–56.
Parker C, Nilsson S, Heinrich D, et al. Alpha emitter radium-223 and survival in metastatic prostate cancer. N Engl J Med. 2013;369:213–23.
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Moran, M.E. (2018). Prostate Cancer and Radiation Therapy: A History. In: Patel, S., Moran, M., Nakada, S. (eds) The History of Technologic Advancements in Urology. Springer, Cham. https://doi.org/10.1007/978-3-319-61691-9_14
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