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Development of the Cerebellum from Molecular Aspects to Diseases

  • Book
  • © 2017

Overview

Editors:
  1. Hassan Marzban

    1. Department of Human Anatomy and Cell Science, The Children’s Hospital Research Institute of Manitoba (CHRIM), Max Rady College of Medicine, Rady Faculty of Health Science, University of Manitoba, Winnipeg, Canada

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  • For research scientists as well as clinicians who treat patients with cerebellar disorders
  • Explores the molecular basis of cerebellar development
  • Written by the top experts in the field
  • Includes supplementary material: sn.pub/extras

Part of the book series: Contemporary Clinical Neuroscience (CCNE)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. The Development of the Cerebellum: From the Beginnings

    • Jan Voogd
    Pages 1-32

  3. The Embryology and Anatomy of the Cerebellum

    • Maryam Rahimi Balaei, Niloufar Ashtari, Hugo Bergen
    Pages 33-43

  4. Cellular and Genetic Programs Underlying Cerebellum Development

    • Alexandra L. Joyner, Ryan Willett, Andrew Lawton
    Pages 45-65

  5. Early Purkinje Cell Development and the Origins of Cerebellar Patterning

    • Filippo Casoni, Laura Croci, Ottavio Cremona, Richard Hawkes, G. Giacomo Consalez
    Pages 67-86

  6. Cerebellar Developmental Disorders and Cerebellar Nuclei

    • Hong-Ting Prekop, Alessio Delogu, Richard J. T. Wingate
    Pages 87-104

  7. Motor Circuit Abnormalities During Cerebellar Development

    • Elizabeth P. Lackey, Roy V. Sillitoe
    Pages 105-127

  8. Developmental Disorders of the Cerebellum and Neurotrophic Factors

    • Leila Pirmoradi, Ali Akbar Owji, Shahla Shojaei
    Pages 129-151

  9. Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development

    • Mohammad Amin Moosavi, Marveh Rahmati, Niloufar Ashtari, Javad Alizadeh, Mohammad Hashemi, Seyedeh Zahra Bathaei et al.
    Pages 153-178

  10. The Ubiquitin Proteasome System and Cerebellar Developmental Disease

    • Jerry Vriend, Xiaodan Jiao
    Pages 179-196

  11. Epigenetics and Cerebellar Neurodevelopmental Disorders

    • Mojgan Rastegar
    Pages 197-218

  12. Hormonal Regulation of Cerebellar Development and Its Disorders

    • Noriyuki Koibuchi
    Pages 219-235

  13. Infections of the Cerebellum

    • Kevin M. Coombs
    Pages 237-253

  14. Neuroimmune Mechanisms of Cerebellar Development and Its Developmental Disorders: Bidirectional Link Between the Immune System and Nervous System

    • Nour Eissa, LaĂ«titia Kermarrec, Jean-Eric Ghia
    Pages 255-274

  15. Teratogenic Influences on Cerebellar Development

    • Albert E. Chudley
    Pages 275-300

  16. Primary Pediatric Brain Tumors of the Posterior Fossa: Part I

    • Kathleen Felton, Amanda Hogg, Lisa Liang, Christopher Aiken, Thomas Klonisch, Frank van Landeghem et al.
    Pages 301-326

  17. Primary Pediatric Brain Tumors of the Posterior Fossa Part II: A Comprehensive Overview of Medulloblastoma

    • Lisa Liang, Christopher Aiken, Kathleen Felton, Amanda Hogg, Frank van Landeghem, T. Klonisch et al.
    Pages 327-351

  18. Can Cerebellar Neurodevelopmental Disorders Affect Behavioral Disorders or Vice Versa?

    • Seyed Soheil Saeedi Saravi, Ahmad Reza Dehpour
    Pages 353-367

  19. Neurodevelopmental Disorders of the Cerebellum: Autism Spectrum Disorder

    • Mehnosh Toback, Kambiz Zangeneh, Tabrez J. Siddiqui, Hassan Marzban
    Pages 369-387

  20. Clinical Aspects of the Inherited Cerebellar Malformations

    • Asghar Marzban, Mohammad Vafaee-shahi, Kamran Azarkhish
    Pages 389-406
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Keywords

About this book

The authors present the most current and cutting-edge knowledge regarding the molecular basis of cerebellar development, focusing on information relevant to laboratory scientists and clinicians providing service to patients with cerebellar disorders. Knowledge obtained from advanced neuroimaging techniques that are used during development, and from molecular- and genetic-based studies has provided rapidly-growing evidence that the cerebellum is a brain region that is highly impacted by developmental defects. Cerebellar defects result in significant intellectual and motor function impairment that affects both the patients and their families.

Editors and Affiliations

  • Department of Human Anatomy and Cell Science, The Children’s Hospital Research Institute of Manitoba (CHRIM), Max Rady College of Medicine, Rady Faculty of Health Science, University of Manitoba, Winnipeg, Canada

    Hassan Marzban

About the editor

Dr. Hassan Marzban (Editor) is a human anatomist and cerebellar developmental biologist, at Department of Human Anatomy and Cell Sciences,  the College of Medicine, Faculty of Health Sciences, University of Manitoba. Dr. Marzban is a pioneer in the field and his research is focused to understand the cellular and molecular mechanisms of the developing cerebellum and neurodevelopmental disorders and disabilities.

Bibliographic Information

  • Book Title: Development of the Cerebellum from Molecular Aspects to Diseases

  • Editors: Hassan Marzban

  • Series Title: Contemporary Clinical Neuroscience

  • DOI: https://doi.org/10.1007/978-3-319-59749-2

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Softcover ISBN: 978-3-319-86693-2Published: 12 August 2018

  • eBook ISBN: 978-3-319-59749-2Published: 27 July 2017

  • Series ISSN: 2627-535X

  • Series E-ISSN: 2627-5341

  • Edition Number: 1

  • Number of Pages: IX, 505

  • Number of Illustrations: 27 b/w illustrations, 70 illustrations in colour

  • Topics: Neurosciences, Neurology

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