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Sustainable Carbododiimine and Triazine Reagents as Collagen Cross-Linking Agents in the Presence of PAMAM Dendrimers

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Sustainable Design and Manufacturing 2017 (SDM 2017)

Part of the book series: Smart Innovation, Systems and Technologies ((SIST,volume 68))

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Abstract

This work reports a general outline on sustainable technologies for the stabilization of collagen and comparative study of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) versus 4-(4,6-dimethoxy [1, 3, 5] triazin-2-yl)-4-methyl-morpholinium chloride (DMTMM) as cross-linking agents of collagen powder. The cross-linking efficiency of these agents on collagen matrixes in the presence of different polyamidoamine dendrimers (PAMAM) has been tested in order to determine the influence of steric hindrance and aminic groups abundance.

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Acknowledgements

The authors acknowledge funding support from Crossing S.r.l. and University Ca’ Foscari Venice.

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Correspondence to V. Beghetto .

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Beghetto, V., Agostinis, L., Gatto, V., Sole, R., Zanette, D., Conca, S. (2017). Sustainable Carbododiimine and Triazine Reagents as Collagen Cross-Linking Agents in the Presence of PAMAM Dendrimers. In: Campana, G., Howlett, R., Setchi, R., Cimatti, B. (eds) Sustainable Design and Manufacturing 2017. SDM 2017. Smart Innovation, Systems and Technologies, vol 68. Springer, Cham. https://doi.org/10.1007/978-3-319-57078-5_42

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  • DOI: https://doi.org/10.1007/978-3-319-57078-5_42

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-57077-8

  • Online ISBN: 978-3-319-57078-5

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