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Itch and Stress

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Abstract

Itch is one of the most common symptoms in dermatology, coexisting both with cutaneous disorders (e.g. atopic dermatitis, urticaria, psoriasis, eczema) and systemic disorders (e.g. renal, hepatic, endocrine or neurological). The occurrence of itch may be very bothersome and significantly reduces the health-related quality of life of an affected person. Pathogenesis of pruritus is not fully understood, although it is currently considered as a separate type of sensation. Stress is a complex term, having several definitions and numerous associations with physical, medical and psychological aspects of an individual’s life. Unsurprisingly, itch and stress are closely related to each other, emphasizing the crucial role of central nervous system in generating, sustaining and exacerbating of these symptoms. Stress may induce or exacerbate pre-existing itch while the presence of itch itself is associated with high levels of stress. A vicious itch-scratch-itch cycle appears in a person suffering from pruritus, leading to scratching, additional stress and further worsening of pruritus. The chapter covers main aspects of pathogenesis of pruritus and stress, reviews most common pruritic dermatoses and their relation with stress and describes current treatment modalities applied to alleviate pruritus and coexisting stress.

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Szepietowski, J.C., Reszke, R. (2017). Itch and Stress. In: França, K., Jafferany, M. (eds) Stress and Skin Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-46352-0_6

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