Abstract
We discuss an overtly “simple approach” to complex biological systems borrowing selectively from theoretical physics. The approach is framed by three maxims, and we show examples of its success in two different applications: investigating cellular robustness at the level of gene regulatory networks and quantifying rare events of DNA replication errors.
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Acknowledgments
The authors would like to thank Professor Julian Blow for innumerable enlightening and inspiring discussions on the research projects described in this chapter.
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Albergante, L., Liu, D., Palmer, S., Newman, T.J. (2016). Insights into Biological Complexity from Simple Foundations. In: Leake, M. (eds) Biophysics of Infection. Advances in Experimental Medicine and Biology, vol 915. Springer, Cham. https://doi.org/10.1007/978-3-319-32189-9_18
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DOI: https://doi.org/10.1007/978-3-319-32189-9_18
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