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Secondary Tumors, Pathology of the Peritoneum

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Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

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Gliomatosis

Definition

Presence of mature glial tissue in the abdominal cavity, most often in association with an immature teratoma, less frequently with mature cystic teratomas, mixed germ cell tumors, and ventriculoperitoneal shunts. The appearance after chemotherapy has been termed “Growing teratoma syndrome.”

Clinical Features

  • Incidence

    Rare.

  • Age

    Children or young adults.

  • Sex

    Affects both genders.

  • Site

    Peritoneum.

  • Treatment

    Surgery.

  • Outcome

    Generally good, except for rare cases with malignant transformation. Recurrence is observed in some cases but is effectively managed surgically.

Macroscopy

Typically multiple small nodules, occasionally larger foci.

Microscopy

Nodules of mature glial tissue, occasionally with fibrosis and inflammation (Figs. 1 and 2).

Figs. 1 and 2
figure 1

Nodules of mature glial cells in an omental resection

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References and Further Reading

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Author information

Authors and Affiliations

  1. Department of Pathology, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway

    Ben Davidson

  2. University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway

    Ben Davidson

Authors
  1. Ben Davidson
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Corresponding author

Correspondence to Ben Davidson .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Davidson, B. (2023). Secondary Tumors, Pathology of the Peritoneum. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5678-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5678-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

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