Abstract
Advances in chemistry during the twentieth century have facilitated the rapid development of a myriad of new chemicals with applications as varied as the needs of humans (Chalew and Halden 2009). However, this ability to quickly synthesize new molecules comes with an inherent risk – that evolutionary mechanisms simply cannot adapt to these new (and potentially toxic) chemical substances quickly enough (Bourret et al. 2008; Whitehead et al. 2012). Thus, some xenobiotics (e.g., novel halogenated organic compounds) have been very challenging for life on earth, since biota often lack the necessary mechanisms for their detoxification, which in turn, may lead to bioaccumulation and biomagnification along food chains. However, it is not just newly synthesised chemicals that represent a hazard to life. A range of human activities also favour the redistribution of naturally occurring toxic substances (such as heavy metals); introduce invasive species that produce toxins (Southard et al. 2010; Bodkin et al. 2012); or, promote favourable environmental conditions for toxins produced by large-scale blooms of algae or bacteria (Watanabe et al. 2011; Anza et al. 2014) – all of which can threaten ecosystems/populations.
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References
Albert CA, Wilson LK, Mineau P, Trudeau S, Elliott JE (2010) Anticoagulant rodenticides in three owl species from Western Canada, 1988–2003. Arch Environ Contam Toxicol 58:451–459
Almeida JR, Oliveira C, Gravato C, Guilhermino L (2010) Linking behavioural alterations with biomarkers responses in the European seabass Dicentrarchus labrax L. exposed to the organophosphate pesticide fenitrothion. Ecotoxicology 19:1369–1381
Alonso MB, Feo ML, Corcellas C, Vidal LG, Bertozzi CP, Marigo J, Secchi ER, Bassoi M, Azevedo AF, Dorneles PR, Torres JP, Lailson-Brito J, Malm O, Eljarrat E, Barceló D (2012) Pyrethroids: a new threat to marine mammals? Environ Int 47:99–106
Andrady AL (2011) Microplastics in the marine environment. Mar Pollut Bull 62:1596–1605
Ankley GT, Bennett RS, Erickson RJ, Hoff DJ, Hornung MW, Johnson RD, Mount DR, Nichols JW, Russom CL, Schmieder PK, Serrrano JA, Tietge JE, Villeneuve DL (2010) Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment. Environ Toxicol Chem 29:730–741
Anza I, Vidal D, Laguna C, Díaz-Sánchez S, Sánchez S, Chicote A, Florín M, Mateo R (2014) Eutrophication and bacterial pathogens as risk factors for avian botulism outbreaks in wetlands receiving effluents from urban wastewater treatment plants. Appl Environ Microbiol 80:4251–4259
Arnold KE, Boxall ABA, Brown R, Cuthbert RJ, Gaw S, Hutchinson TH, Jobling S, Madden JC, Metcalfe CD, Naidoo V, Shore RF, Smits JE, Taggart MA, Thompson HM (2013) Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems. Biol Lett 9:20130492
Baker ME, Ruggeri B, Sprague LJ, Eckhardt-Ludka C, Lapira J, Wick I, Soverchia L, Ubaldi M, Polzonetti-Magni AM, Vidal-Dorsch D, Bay S, Gully JR, Reyes JA, Kelley KM, Schlenk D, Breen EC, Šášik R, Hardiman G (2009) Analysis of endocrine disruption in southern California coastal fish using an aquatic multispecies microarray. Environ Health Perspect 117:223–230
Baldwin DH, Spromberg JA, Collier TK, Scholz NL (2009) A fish of many scales: extrapolating sublethal pesticide exposures to the productivity of wild salmon populations. Ecol Appl 19:2004–2015
Bars R, Fegert I, Gross M, Lewis D, Weltje L, Weyers A, Wheeler JR, Galay-Burgos M (2012) Risk assessment of endocrine active chemicals: identifying chemicals of regulatory concern. Regul Toxicol Pharmacol 64:143–154
Basu N, Klenavic K, Gamberg M, O’Brien M, Evans D, Scheuhammer AM, Hing MC (2005) Effects of mercury on neurochemical receptor-binding characteristics in wild mink. Environ Toxicol Chem 24:1444–1450
Basu N, Scheuhammer AM, Sonne C, Letcher RJ, Born EW, Dietz R (2009) Is dietary mercury of neurotoxicological concern to wild polar bears (Ursus maritimus)? Environ Toxicol Chem 28:133–140
Bean TG, Boxall ABA, Lane J, Herborn KA, Pietravalle S, Arnold KE (2014) Behavioural and physiological responses of birds to environmentally relevant concentrations of an antidepressant. Philos Trans R Soc B 369:20130575
Benninghoff AD (2007) Toxicoproteomics – The next step in the evolution of environmental biomarkers? Toxicol Sci 95:1–4
Berny PJ, Buronfosse T, Buronfosse F, Lamarque F, Lorgue G (1997) Field evidence of secondary poisoning of foxes (Vulpes vulpes) and buzzards (Buteo buteo) by bromadiolone, a 4-year survey. Chemosphere 35:1817–1829
Beyer WN, Meador JP (eds) (2011) Environmental contaminants in biota: interpreting tissue concentrations. CRC Press, Boca Raton, 751 pp
Beyer WN, Gaston G, Brazzle R, O’Connell AF Jr, Audet DJ (2007) Deer exposed to exceptionally high concentrations of lead near the Continental Mine in Idaho, USA. Environ Toxicol Chem 26:1040–1046
Bodkin JL, Ballachey BE, Coletti HA, Esslinger GG, Kloecker KA, Rice SD, Reed JA, Monson DH (2012) Long-term effects of the ‘Exxon Valdez’ oil spill: sea otter foraging in the intertidal as a pathway of exposure to lingering oil. Mar Ecol Prog Ser 447:273–287
Bortolotti GR (2010) Flaws and pitfalls in the chemical analysis of feathers: bad news-good news for avian chemoecology and toxicology. Ecol Appl 20:1766–1774
Bourret V, Couture P, Campbell PGC, Bernatchez L (2008) Evolutionary ecotoxicology of wild yellow perch (Perca flavescens) populations chronically exposed to a polymetallic gradient. Aquat Toxicol 86:76–90
Boxall ABA, Rudd MA, Brooks BW, Caldwell DJ, Choi K, Hickmann S, Innes E, Ostapyk K, Staveley JP, Verslycke T, Ankley GT, Beazley KF, Belanger SE, Berninger JP, Carriquiriborde P, Coors A, DeLeo PC, Dyer SD, Ericson JF, Gagné F, Giesy JP, Gouin T, Hallstrom L, Karlsson MV, Joakim Larsson DG, Lazorchakm JM, Mastrocco F, McLaughlin A, McMaster ME, Meyerhoff RD, Moore R, Parrott JL, Snape JR, Murray-Smith R, Servos MR, Sibley PK, Straub JO, Szabo ND, Topp E, Tetreault GR, Trudeau VL, Van Der Kraak G (2012) Pharmaceuticals and personal care products in the environment: what are the big questions? Environ Health Perspect 120:1221–1229
Brar NK, Waggoner C, Reyes JA, Fairey R, Kelley KM (2010) Evidence for thyroid endocrine disruption in wild fish in San Francisco Bay, California, USA. Relationships to contaminant exposures. Aquat Toxicol 96:203–215
Brodin T, Fick J, Jonsson M, Klaminder J (2013) Dilute concentrations of a psychiatric drug alter behavior of fish from natural populations. Science 339:814–815
Burkholder J, Libra B, Weyer P, Heathcote S, Kolpin D, Thorne PS, Wichman M (2007) Impacts of waste from concentrated animal feeding operations on water quality. Environ Health Perspect 115:308–312
Bustnes JO (2007) Pinpointing potential causative agents in mixtures of persistent organic pollutants in observational field studies: a review of glaucous gull studies. J Toxicol Environ Health A 68:97–108
Cardiel IE, Taggart MA, Mateo R (2011) Use of the ratio Pb-Al to discriminate between internal and external deposition of Pb in feathers. Ecotoxicol Environ Saf 74:911–917
Carson R (1962) Silent spring. Haughton Mifflin, Boston
Casanova-Nakayama A, Wenger M, Burki R, Eppler E, Krasnov A, Segner H (2011) Endocrine disrupting compounds: can they target the immune system of fish? Mar Pollut Bull 63:412–416
Celander MC (2011) Cocktail effects on biomarker responses in fish. Aquat Toxicol 105(3–4 Suppl):72–77
Chalew TEA, Halden RU (2009) Environmental exposure of aquatic and terrestrial biota to triclosan and triclocarban. J Am Water Resour Assoc 45:4–13
Chipperfield MP, Dhomse SS, Feng W, McKenzie RL, Velders GJ, Pyle JA (2015) Quantifying the ozone and ultraviolet benefits already achieved by the Montreal Protocol. Nat Commun 6:7233
Colles A, Koppen G, Hanot V, Nelen V, Dewolf M-C, Noël E, Malisch R, Kotz A, Kypke K, Biot P, Vinkx C, Schoeters G (2008) Fourth WHO-coordinated survey of human milk for persistent organic pollutants (POPs): Belgian results. Chemosphere 73:907–914
Cortinovis S, Galassi S, Melone G, Saino N, Porte C, Bettinetti R (2008) Organochlorine contamination in Crested Grebe (Podiceps cristatus). Effects on eggshell thickness and egg steroid levels. Chemosphere 73:320–325
Cui B, Zhang Q, Zhang K, Liu X, Zhang H (2011) Analyzing trophic transfer of heavy metals for food webs in the newly-formed wetlands of the Yellow River Delta, China. Environ Pollut 159:1297–1306
Custer CM (2011) Swallows as sentinel species for contaminant exposure and effect studies. In: Elliott JE, Bishop CA, Morrissey CA (eds) Wildlife ecotoxicology: forensic approaches, emerging topics in ecotoxicology 3. Springer, New York, pp 45–91
Cuthbert R, Parry-Jones J, Green RE, Pain DJ (2007) NSAIDs and scavenging birds: potential impacts beyond Asia’s critically endangered vultures. Biol Lett 3:90–93
Cuthbert RJ, Taggart MA, Prakash V, Chakraborty SS, Deori P, Galligan T, Kulkarni M, Ranade S, Saini M, Sharma AK, Shringarpure R, Green RE (2014) Avian scavengers and the threat from veterinary pharmaceuticals. Philos Trans R Soc B 369:20130574
Decaëns T, Jiménez JJ, Gioia C, Measey GJ, Lavelle P (2006) The values of soil animals for conservation biology. Eur J Soil Biol 42:S23–S38
Dowding CV, Shore RF, Worgan A, Baker PJ, Harris S (2010) Accumulation of anticoagulant rodenticides in a non-target insectivore, the European hedgehog (Erinaceus europaeus). Environ Pollut 158:161–166
Dullinger S, Essl F, Rabitsch W, Erb KH, Gingrich S, Haberl H, Hülber K, Jarosík V, Krausmann F, Kühn I, Pergl J, Pysek P, Hulme PE (2013) Europe’s other debt crisis caused by the long legacy of future extinctions. Proc Natl Acad Sci U S A 110:7342–7347
Eason CT, Murphy EC, Wright GR, Spurr EB (2002) Assessment of risks of brodifacoum to non-target birds and mammals in New Zealand. Ecotoxicology 11:35–48
Eens M, Jaspers VLB, Van den Steen E, Bateson M, Carere C, Clergeau P, Costantini D, Dolenec Z, Elliott JE, Flux J, Gwinner H, Halbrook RS, Heeb P, Mazgajski TD, Moksnes A, Polo V, Soler JJ, Sinclair R, Veiga JP, Williams TD, Covaci A, Pinxten R (2013) Can starling eggs be useful as a biomonitoring tool to study organohalogenated contaminants on a worldwide scale? Environ Int 51:141–149
Ek KH, Rauch S, Morrison GM, Lindberg P (2004) Platinum group elements in raptor eggs, faeces, blood, liver and kidney. Sci Total Environ 334–335:149–159
Elliott JE, Elliott KH (2013) Tracking marine pollution. Science 340:556–558
Elliott JE, Birmingham AL, Wilson LK, McAdie M, Trudeau S, Mineau P (2008) Fonofos poisons raptors and waterfowl several months after granular application. Environ Toxicol Chem 27:452–460
Elliott JE, Bishop CA, Morrissey CA (eds) (2011) Wildlife ecotoxicology: forensic approaches, emerging topics in ecotoxicology 3. Springer, New York
Fernie KJ, Shutt JL, Letcher RJ, Ritchie JI, Sullivan K, Bird DM (2008) Changes in reproductive courtship behaviors of adult American kestrels (Falco sparverius) exposed to environmentally relevant levels of the polybrominated diphenyl ether mixture, DE-71. Toxicol Sci 102:171–178
Fernie KJ, Shutt L, Letcher RJ, Ritchie IJ, Bird DM (2009) Environmentally relevant concentration of DE-71 and HBCD alter eggshell thickness and reproductive success of American kestrels. Environ Sci Tech 43:2124–2130
Fick J, Lindberg RH, Tysklind M, Larsson DGJ (2010) Predicted critical environmental concentrations for 500 pharmaceuticals. Regul Toxicol Pharmacol 58:516–523
Finkelstein ME, Doak DF, George D, Burnett J, Brandt J, Church M, Grantham J, Smith DR (2012) Lead poisoning and the deceptive recovery of the critically endangered California condor. Proc Natl Acad Sci U S A 109:11449–11454
Fisher IJ, Pain DJ, Thomas VG (2006) A review of lead poisoning from ammunition sources in terrestrial birds. Biol Conserv 131:421–432
Fox GA (2001) Wildlife as sentinels of human health effects in the Great Lakes--St. Lawrence basin. Environ Health Perspect 109(Suppl 6):853–861
Frederick P, Jayasena N (2011) Altered pairing behaviour and reproductive success in white ibises exposed to environmentally relevant concentrations of methylmercury. Proc R Soc B Biol Sci 278:1851–1857
Gabriel MW, Woods LW, Poppenga R, Sweitzer RA, Thompson C, Matthews SM, Higley JM, Keller SM, Purcell K, Barrett RH, Wengert GM, Sacks BN, Clifford DL (2012) Anticoagulant rodenticides on our public and community lands: spatial distribution of exposure and poisoning of a rare forest carnivore. PLoS One 7, e40163
Gagné F, André C, Skirrow R, Gélinas M, Auclair J, van Aggelen G, Turcotte P, Gagnon C (2012) Toxicity of silver nanoparticles to rainbow trout: a toxicogenomic approach. Chemosphere 89:615–622
Gaiser BK, Fernandes TF, Jepson MA, Lead JR, Tyler CR, Baalousha M, Biswas A, Britton GJ, Cole PA, Johnston BD, Ju-Nam Y, Rosenkranz P, Scown TM, Stone V (2012) Interspecies comparisons on the uptake and toxicity of silver and cerium dioxide nanoparticles. Environ Toxicol Chem 31:144–154
García-Fernández AJ, Espín S, Martínez-López E (2013) Feathers as a biomonitoring tool of polyhalogenated compounds: a review. Environ Sci Tech 47:3028–3043
Gibbons D, Morrissey C, Mineau P (2015) A review of the direct and indirect effects of neonicotinoids and fipronil on vertebrate wildlife. Environ Sci Pollut Res Int 22:103–118
Gill RJ, Ramos-Rodriguez O, Raine NE (2012) Combined pesticide exposure severely affects individual-and colony-level traits in bees. Nature 491:105–108
Gómez-Ramírez P, Shore RF, van den Brink NW, van Hattum B, Bustnes JO, Duke G, Fritsch C, García-Fernández AJ, Helander BO, Jaspers V, Krone O, Martínez-López E, Mateo R, Movalli P, Sonne C (2014) An overview of existing raptor contaminant monitoring activities in Europe. Environ Int 67:12–21
Goulson D (2014) Ecology: pesticides linked to bird declines. Nature 511:295–296
Green RE, Pain DJ (2012) Potential health risks to adults and children in the UK from exposure to dietary lead in gamebirds shot with lead ammunition. Food Chem Toxicol 50:4180–4190
Gregory MR (2009) Environmental implications of plastic debris in marine settings--entanglement, ingestion, smothering, hangers-on, hitch-hiking and alien invasions. Philos Trans R Soc B 364:2013–2025
Guertin DA, Harestad AS, Ben‐David M, Drouillard KG, Elliott JE (2010) Fecal genotyping and contaminant analyses reveal variation in individual river otter exposure to localized persistent contaminants. Environ Toxicol Chem 29:275–284
Guertin DA, Ben‐David M, Harestad AS, Elliott JE (2012) Fecal genotyping reveals demographic variation in river otters inhabiting a contaminated environment. J Wildl Manag 76:1540–1550
Gunnarsson L, Jauhiainen A, Kristiansson E, Nerman O, Larsson DGJ (2008) Evolutionary conservation of human drug targets in organisms used for environmental risk assessments. Environ Sci Tech 42:5807–5813
Gunnarsson L, Kristiansson E, Rutgersson C, Sturve J, Fick J, Förlin L, Larsson DGJ (2009) Pharmaceutical industry effluent diluted 1:500 affects global gene expression, cytochrome P450 1A activity, and plasma phosphate in fish. Environ Toxicol Chem 28:2639–2647
Gutleb AC, Cenijn P, Velzen MV, Lie E, Ropstad E, Skaare JU, Malmberg T, Bergman Å, Gabrielsen GW, Legler J (2010) In vitro assay shows that PCB metabolites completely saturate thyroid hormone transport capacity in blood of wild polar bears (Ursus maritimus). Environ Sci Tech 44:3149–3154
Hallmann CA, Foppen RP, van Turnhout CA, de Kroon H, Jongejans E (2014) Declines in insectivorous birds are associated with high neonicotinoid concentrations. Nature 511:341–343
Harris CA, Hamilton PB, Runnalls TJ, Vinciotti V, Henshaw A, Hodgson D, Coe TS, Jobling S, Tyler CR, Sumpter JP (2011) The consequences of feminization in breeding groups of wild fish. Environ Health Perspect 119:306–311
Hartwig E, Clemens T, Heckroth M (2007) Plastic debris as nesting material in a Kittiwake (Rissa tridactyla) colony at the Jammerbugt, Northwest Denmark. Mar Pollut Bull 54:595–597
Heath JA, Frederick PC (2005) Relationships among mercury concentrations, hormones, and nesting effort of White Ibises (Eudocimus albus) in the Florida Everglades. Auk 122:255–267
Hecker M, Hollert H, Cooper R, Vinggaard A-M, Akahori Y, Murphy M, Nellemann C, Higley E, Newsted J, Wu R, Lam P, Laskey J, Buckalew A, Grund S, Nakai M, Timm G, Giesy J (2007) The OECD validation program of the H295R steroidogenesis assay for the identification of in vitro inhibitors and inducers of testosterone and estradiol production. Phase 2: inter-laboratory pre-validation studies. Environ Sci Pollut Res 14(1 Special Issue):23–30
Hendriks AJ, Maas-Diepeveen JL, Heugens EH, Van Straalen NM (2005) Meta-analysis of intrinsic rates of increase and carrying capacity of populations affected by toxic and other stressors. Environ Toxicol Chem 24:2267–2277
Henny CJ, Kaiser JL, Grove RA, Johnson BL, Letcher RJ (2009) Polybrominated diphenyl ether flame retardants in eggs may reduce reproductive success of ospreys in Oregon and Washington, USA. Ecotoxicology 18:802–813
Henry M, Beguin M, Requier F, Rollin O, Odoux JF, Aupinel P, Aptel J, Tchamitchian S, Decourtye A (2012) A common pesticide decreases foraging success and survival in honey bees. Science 336:348–350
Hoffman DJ, Rattner BA, Burton GA Jr, Cairns J Jr (eds) (2003) Handbook of ecotoxicology. Publisher Lewis Publishers, Boca Raton
Houde M, Muir DCG, Tomy GT, Whittle DT, Teixeira C, Moore S (2008) Bioaccumulation and trophic magnification of short- and medium-chain chlorinated paraffins in food webs from Lake Ontario and Lake Michigan. Environ Sci Tech 42:3893–3899
Houde M, De Silva AO, Muir DCG, Letcher RJ (2011) Monitoring of perfluorinated compounds in aquatic biota: an updated review. Environ Sci Tech 45:7962–7973
Ikemoto T, Kunito T, Tanaka H, Baba N, Miyazaki N, Tanabe S (2004) Detoxification mechanism of heavy metals in marine mammals and seabirds: interaction of selenium with mercury, silver, copper, zinc, and cadmium in liver. Arch Environ Contam Toxicol 47:402–413
Jackson AK, Evers DC, Etterson MA, Condon AM, Folsom SB, Detweiler J, Schmerfeld J, Cristol DA (2011) Mercury exposure affects the reproductive success of a free-living terrestrial songbird, the carolina wren (Thryothorus ludovicianus). Auk 128:759–769
Jagannath A, Shore RF, Walker LA, Ferns PN, Gosler AG (2008) Eggshell pigmentation indicates pesticide contamination. J Appl Ecol 45:133–140
Jaspers VL, Covaci A, Deleu P, Neels H, Eens M (2008) Preen oil as the main source of external contamination with organic pollutants onto feathers of the common magpie (Pica pica). Environ Int 34:741–748
Jaspers VL, Covaci A, Deleu P, Eens M (2009) Concentrations in bird feathers reflect regional contamination with organic pollutants. Sci Total Environ 407:1447–1451
Jobling S, Williams R, Johnson A, Taylor A, Gross-Sorokin M, Nolan M, Tyler CR, Van Aerle R, Santos E, Brighty G (2006) Predicted exposures to steroid estrogens in UK rivers correlate with widespread sexual disruption in wild fish populations. Environ Health Perspect 114:32–39
Johansen P, Muir D, Asmund G, Riget F (2004) Human exposure to contaminants in the traditional Greenland diet. Sci Total Environ 331:189–206
Karchner SI, Franks DG, Kennedy SW, Hahn ME (2006) The molecular basis for differential dioxin sensitivity in birds: role of the aryl hydrocarbon receptor. Proc Natl Acad Sci U S A 103:6252–6257
Kidd KA, Blanchfield PJ, Mills KH, Palace VP, Evans RE, Lazorchak JM, Flick RW (2007) Collapse of a fish population after exposure to a synthetic estrogen. Proc Natl Acad Sci U S A 104:8897–8901
La Merrill M, Emond C, Kim MJ, Antignac JP, Le Bizec B, Clément K, Birnbaum LS, Barouki R (2013) Toxicological function of adipose tissue: focus on persistent organic pollutants. Environ Health Perspect 121:162–169
Lahr J, Münier B, De Lange HJ, Faber JF, Sørensen PB (2010) Wildlife vulnerability and risk maps for combined pollutants. Sci Total Environ 408:3891–3898.
Landis WG, Chapman PM (2011) Well past time to stop using NOELs and LOELs. Integr Environ Assess Manag 7:vi–viii
Larsson DGJ, de Pedro C, Paxeus N (2007) Effluent from drug manufactures contains extremely high levels of pharmaceuticals. J Hazard Mater 148:751–755
Laskowski R, Bednarska AJ, Kramarz PE, Loureiro S, Scheil V, Kudłek J, Holmstrup M (2010) Interactions between toxic chemicals and natural environmental factors – a meta-analysis and case studies. Sci Total Environ 408:3763–3774
Lavoie RA, Kyser TK, Friesen VL, Campbell LM (2015) Tracking overwintering areas of fish-eating birds to identify mercury exposure. Environ Sci Technol 49:863–872
Laycock I, Lenthall KM, Barratt AT, Cresswell JE (2012) Effects of imidacloprid, a neonicotinoid pesticide, on reproduction in worker bumble bees (Bombus terrestris). Ecotoxicology 21:1937–1945
Lazarus RS, Rattner BA, Brooks BW, Du B, McGowan PC, Blazer VS, Ottinger MA (2015) Exposure and food web transfer of pharmaceuticals in ospreys (Pandion haliaetus): predictive model and empirical data. Integr Environ Assess Manag 11:118–129
Lemarchand C, Rosoux R, Berny P (2010) Organochlorine pesticides, PCBs, heavy metals and anticoagulant rodenticides in tissues of Eurasian otters (Lutra lutra) from upper Loire River catchment (France). Chemosphere 80:1120–1124
Letcher RJ, Bustnes JO, Dietz R, Jenssen BM, Jørgensen EH, Sonne C, Verreault J, Vijayan MM, Gabrielsen GW (2010) Exposure and effects assessment of persistent organohalogen contaminants in arctic wildlife and fish. Sci Total Environ 408:2995–3043
Li Y, Yu S, Wu Q, Tang M, Pu Y, Wang D (2012) Chronic Al 2O 3-nanoparticle exposure causes neurotoxic effects on locomotion behaviors by inducing severe ROS production and disruption of ROS defense mechanisms in nematode Caenorhabditis elegans. J Hazard Mater 219–220:221–230
Lilienthal H, Hack A, Roth-Härer A, Wichert Grande S, Talness CE (2006) Effects of developmental exposure to 2,2′,4,4′,5-pentabromodiphenyl ethter (PBDE-99) on sex steroids, sexual development, and sexually dimorphic behaviour in rats. Environ Health Perspect 114:196–201
Liu X, Vinson D, Abt D, Hurt RH, Rand DM (2009) Differential toxicity of carbon nanomaterials in Drosophila: larval dietary uptake is benign, but adult exposure causes locomotor impairment and mortality. Environ Sci Tech 43:6357–6363
López-Antia A, Ortiz-Santaliestra ME, Mateo R (2014) Experimental approaches to test pesticide-treated seed avoidance by birds under a simulated diversification of food sources. Sci Total Environ 496:179–187
López-Antia A, Ortiz-Santaliestra ME, Mougeot F, Mateo R (2015) Imidacloprid-treated seed ingestion has lethal effect on adult partridges and reduces both breeding investment and offspring immunity. Environ Res 136:97–107
Lovvorn JR, Raisbeck MF, Cooper LW, Cutter GA, Miller MW, Brooks ML, Grebmeier JM, Matz AC, Schaefer CM (2013) Wintering eiders acquire exceptional Se and Cd burdens in the Bering Sea: physiological and oceanographic factors. Mar Ecol Prog Ser 489:245–261
Luttik R, Mineau P, Roelofs W (2005) A review of interspecies toxicity extrapolation in birds and mammals and a proposal for long-term toxicity data. Ecotoxicology 14:817–832
Mahler GJ, Esch MB, Tako E, Southard TL, Archer SD, Glahn RP, Shuler ML (2012) Oral exposure to polystyrene nanoparticles affects iron absorption. Nat Nanotechnol 7:264–271
Margalida A, Bogliani G, Bowden CGR, Donázar JA, Genero F, Gilbert M, Karesh W, Kock R, Lubroth J, Manteca X, Naidoo V, Neimanis A, Sánchez-Zapata JA, Taggart MA, Vaarten J, Yon L, Kuiken T, Green RE (2014) One health approach to the use of veterinary pharmaceuticals. Science 346:1296–1298
Martínez-Haro M, Mateo R, Guitart R, Soler-Rodríguez F, Pérez-López M, María-Mojica P, García-Fernández AJ (2008) Relationship of the toxicity of pesticide formulations and their commercial restrictions with the frequency of animal poisonings. Ecotoxicol Environ Saf 69:396–402
Martinez-Haro M, Taggart MA, Rodríguez Martín-Doimeadios R, Green AJ, Mateo R (2011) Identifying sources of Pb exposure in waterbirds and effects on porphyrin metabolism using non-invasive fecal sampling. Environ Sci Tech 45:6153–6159
Mateo R (2009) Lead poisoning in wild birds in Europe and the regulations adopted by different countries. In: Watson RT, Fuller M, Pokras M, Hunt WG (eds) Ingestion of lead from spent ammunition: implications for wildlife and humans. The Peregrine Fund, Boise, pp 71–98
Mateo R, Beyer WN, Spann JW, Hoffman DJ, Ramis A (2003) Relationship between oxidative stress, pathology, and behavioral signs of lead poisoning in mallards. J Toxicol Environ Health A 66:1371–1389
Mateo R, Taggart M, Green AJ, Cristòfol C, Ramis A, Lefranc H, Figuerola J, Meharg AM (2006) Altered porphyrin excretion and histopathology of greylag geese (Anser anser) exposed to soil contaminated with lead and arsenic in the Guadalquivir Marshes, SW Spain. Environ Toxicol Chem 25:203–212
Mateo R, Vallverdú-Coll N, López-Antia A, Taggart MA, Martínez-Haro M, Guitart R, Ortiz-Santaliestra ME (2014) Reducing Pb poisoning in birds and Pb exposure in game meat consumers: the dual benefit of effective Pb shot regulation. Environ Int 63:163–168
Matranga V, Corsi I (2012) Toxic effects of engineered nanoparticles in the marine environment: model organisms and molecular approaches. Mar Environ Res 76:32–40
McKinlay R, Plant JA, Bell JNB, Voulvoulis N (2008) Endocrine disrupting pesticides: implications for risk assessment. Environ Int 34:168–183
Meyer JN, Lord CA, Yang XY, Turner EA, Badireddy AR, Marinakos SM, Chilkoti A, Wiesner MR, Auffan M (2010) Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans. Aquat Toxicol 100:140–150
Miller DH, Jensen KM, Villeneuve DL, Kahl MD, Makynen EA, Durhan EJ, Ankley GT (2007) Linkage of biochemical responses to population-level effects: a case study with vitellogenin in the fathead minnow (Pimephales promelas). Environ Toxicol Chem 26:521–527
Mineau P (2005) A review and analysis of study endpoints relevant to the assessment of “long term” pesticide toxicity in avian and mammalian wildlife. Ecotoxicology 14:775–799
Mommaerts V, Reynders S, Boulet J, Besard L, Sterk G, Smagghe G (2010) Risk assessment for side-effects of neonicotinoids against bumblebees with and without impairing foraging behaviour. Ecotoxicology 19:207–215
Moore CJ (2008) Synthetic polymers in the marine environment: a rapidly increasing, long-term threat. Environ Res 108:131–139
Movalli P, Duke G (eds) (2008) Monitoring for and with raptors. Ambio (Special issue) 37
Murray M (2011) Anticoagulant rodenticide exposure and toxicosis in four species of birds of prey presented to a wildlife clinic in Massachusetts, 2006–2010. J Zoo Wildl Med 42:88–97
Murvoll KM, Skaare JU, Anderssen E, Jenssen BM (2006) Exposure and effects of persistent organic pollutants in European shag (Phalacrocorax aristotelis) hatchlings from the coast of Norway. Environ Toxicol Chem 25:190–198
Naidoo V, Wolter K, Cromarty D, Diekmann M, Duncan N, Meharg AA, Taggart MA, Venter L, Cuthbert R (2010) Toxicity of non-steroidal anti-inflammatory drugs to Gyps vultures: a new threat from ketoprofen. Biol Lett 6:339–341
Nash JP, Kime DE, Van der Ven LTM, Wester PW, Brion F, Maack G, Stahlschmidt-Allner P, Tyler CR (2004) Long-term exposure to environmental concentrations of the pharmaceutical ethynylestradiol causes reproductive failure in fish. Environ Health Perspect 112:1725–1733
Noël M, Spence J, Harris KA, Robbins CT, Fortin JK, Ross PS, Christensen JR (2014) Grizzly bear hair reveals toxic exposure to mercury through salmon consumption. Environ Sci Tech 48:7560–7567
Oaks JL, Gilbert M, Virani MZ, Watson RT, Meteyer CU, Rideout BA, Shivaprasad HL, Ahmed S, Chaudhry MJI, Arshad M, Mahmood S, Ali A, Khan AA (2004) Diclofenac residues as the cause of vulture population decline in Pakistan. Nature 427:630–633
Oehlmann J, Schulte-Oehlmann U, Kloas W, Jagnytsch O, Lutz I, Kusk KO, Wollenberger L, Santos EM, Paull GC, Van Look KJW, Tyler CR (2009) A critical analysis of the biological impacts of plasticizers on wildlife. Philos Trans R Soc B 364:2047–2062
Pilsner JR, Lazarus AL, Nam D-H, Letcher RJ, Sonne C, Dietz R, Basu N (2010) Mercury-associated DNA hypomethylation in polar bear brains via the LUminometric methylation assay: a sensitive method to study epigenetics in wildlife. Mol Ecol 19:307–314
Poletta GL, Kleinsorge E, Paonessa A, Mudry MD, Larriera A, Siroski PA (2011) Genetic, enzymatic and developmental alterations observed in Caiman latirostris exposed in ovo to pesticide formulations and mixtures in an experiment simulating environmental exposure. Ecotoxicol Environ Saf 74:852–859
Prosser P, Hart AD (2005) Assessing potential exposure of birds to pesticide-treated seeds. Ecotoxicology 14:679–691
Raimondo S, Vivian DN, Delos C, Barron MG (2008) Protectiveness of species sensitivity distribution hazard concentrations for acute toxicity used in endangered species risk assessment. Environ Toxicol Chem 27:2599–2607
Rattner BA, Horak KE, Warner SE, Day DD, Meteyer CU, Volker SF, Eisemann JD, Johnston JJ (2011) Acute toxicity, histopathology, and coagulopathy in American kestrels (Falco sparverius) following administration of the rodenticide diphacinone. Environ Toxicol Chem 30:1213–1222
Rattner BA, Lazarus RS, Elliott JE, Shore RF, van den Brink N (2014) Adverse outcome pathway and risks of anticoagulant rodenticides to predatory wildlife. Environ Sci Tech 48:8433–8445
Reid N, Thompson D, Hayden B, Marnell F, Montgomery WI (2013) Review and quantitative meta-analysis of diet suggests the Eurasian otter (Lutra lutra) is likely to be a poor bioindicator. Ecol Indic 26:5–13
Richards N (ed) (2012) Carbofuran and wildlife poisoning: global perspective and forensic approaches. Wiley-Blackwell, Chichester
Richards NL, Cook G, Simpson V, Hall S, Harrison N, Scot t KS (2011) Qualitative detection of the NSAIDs diclofenac and ibuprofen in the hair of Eurasian otters (Lutra lutra) occupying UK waterways with GC-MS. Eur J Wildl Res 57:1107–1114
Riley SPD, Bromley C, Poppenga RH, Uzal FA, Whited L, Sauvajot RM (2007) Anticoagulant exposure and notoedric mange in bobcats and mountain lions in urban Southern California. J Wildl Manag 71:1874–1884
Ross P, Birbaum L (2003) Integrated human and ecological risk assessment: a case study of Persistent Organic Pollutants (POPs) in humans and wildlife. Human Toxicol Risk Assess 9:303–324
Sánchez-Barbudo IS, Camarero PR, Mateo R (2012) Primary and secondary poisoning by anticoagulant rodenticides of non-target animals in Spain. Sci Total Environ 420:280–288
Sarabia J, Sánchez-Barbudo IS, Siqueira W, Mateo R, Rolla E, Pizarro M (2008) Lesions associated with the plexus venosus subcutaneus collaris of pigeons with chlorophacinone toxicosis. Avian Dis 52:540–543
Scheifler R, Cœurdassier M, Morilhat C, Bernard N, Faivre B, Flicoteaux P, Giraudoux P, Noël M, Piotte P, Rieffel D, de Vaufleury A, Badot P-M (2006) Lead concentrations in feathers and blood of common blackbirds (Turdus merula) and in earthworms inhabiting unpolluted and moderately polluted urban areas. Sci Total Environ 371:197–205
Scholz S, Sela E, Blaha L, Braunbeck T, Galay-Burgos M, García-Franco M, Guinea J, Klüver N, Schirmer K, Tanneberger K, Tobor-Kapłon M, Witters H, Belanger S, Benfenati E, Creton S, Cronin MTD, Eggen RIL, Embry M, Ekman D, Gourmelon A, Halder M, Hardy B, Hartung T, Hubesch B, Jungmann D, Lampi MA, Lee L, Léonard M, Küster E, Lillicrap A, Luckenbach T, Murk AJ, Navas JM, Peijnenburg W, Repetto G, Salinas E, Schüürmann G, Spielmann H, Tollefsen KE, Walter-Rohde S, Whale G, Wheeler JR, Winter MJ (2013) A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment. Regul Toxicol Pharmacol 67:506–530
Seitz F, Bundschuh M, Rosenfeldt RR, Schulz R (2013) Nanoparticle toxicity in Daphnia magna reproduction studies: the importance of test design. Aquat Toxicol 126:163–168
Shaw SD, Brenner D, Bourakovsky A, Mahaffey CA, Perkins CR (2005) Polychlorinated biphenyls and chlorinated pesticides in harbor seals (Phoca vitulina concolor) from the northwestern Atlantic coast. Mar Pollut Bull 50:1069–1084
Shore RF, Malcolm HM, Mclennan D, Turk A, Walker LA, Wienburg CL, Burn AJ (2006) Did foot-and-mouth disease-control operations affect rodenticide exposure in raptors? J Wildl Manag 70:588–593
Shore RF, Taggart MA, Smits J, Mateo R, Richards NL, Fryday S (2014) Detection and drivers of exposure and effects of pharmaceuticals in higher vertebrates. Philos Trans R Soc (London) B 369:20130570
Simpson VR, Tomlinson AJ, Molenaar FM, Lawson B, Rogers KD (2011) Renal calculi in wild Eurasian otters (Lutra lutra) in England. Vet Rec 169:49
Snape JR, Maund SJ, Pickford DB, Hutchinson TH (2004) Ecotoxicogenomics: the challenge of integrating genomics into aquatic and terrestrial ecotoxicology. Aquat Toxicol 67:143–154
Southard GM, Fries LT, Barkoh A (2010) Prymnesium parvum: the Texas experience. J Am Water Resour Assoc 46:14–23
Souza DM, Teixeira RF, Ostermann OP (2015) Assessing biodiversity loss due to land use with life cycle assessment: are we there yet? Glob Chang Biol 21:32–47
Stahl T, Mattern D, Brunn H (2011) Toxicology of perfluorinated compounds. Environ Sci Eur 23:38
Taggart MA, Reglero MM, Camarero PR, Mateo R (2011) Should legislation regarding maximum heavy metal levels in human food also cover large game meat? Environ Int 37:18–25
Tartu S, Goutte A, Bustamante P, Angelier F, Moe B, Clément-Chastel C, Bech C, Gabrielsen GW, Bustnes JO, Chastel O (2013) To breed or not to breed: endocrine response to mercury contamination by an Arctic seabird. Biol Lett 9:20130317
Teuten EL, Saquing JM, Knappe DR, Barlaz MA, Jonsson S, Björn A, Rowland SJ, Thompson RC, Galloway TS, Yamashita R, Ochi D, Watanuki Y, Moore C, Viet PH, Tana TS, Prudente M, Boonyatumanond R, Zakaria MP, Akkhavong K, Ogata Y, Hirai H, Iwasa S, Mizukawa K, Hagino Y, Imamura A, Saha M, Takada H (2009) Transport and release of chemicals from plastics to the environment and to wildlife. Philos Trans R Soc B 364:2027–2045
Thomas PJ, Mineau P, Shore RF, Champoux L, Martin PA, Wilson LK, Fitzgerald G, Elliott JE (2011) Second generation anticoagulant rodenticides in predatory birds: probabilistic characterisation of toxic liver concentrations and implications for predatory bird populations in Canada. Environ Int 37:914–920
Topping CJ, Odderskær P (2004) Modeling the influence of temporal and spatial factors on the assessment of impacts of pesticides on skylarks. Environ Toxicol Chem 23:509–520
Ucán-Marín F, Arukwe A, Mortensen A, Gabrielsen GW, Fox GA, Letcher RJ (2009) Recombinant transthyretin purification and competitive binding with organohalogen compounds in two gull species (Larus argentatus and Larus hyperboreus). Toxicol Sci 107:440–450
van Zelm R, Larrey-Lassalle P, Roux P (2014) Bridging the gap between life cycle inventory and impact assessment for toxicological assessments of pesticides used in crop production. Chemosphere 100:175–181
Vandegehuchte MB, Janssen CR (2014) Epigenetics in an ecotoxicological context. Mutat Res Genet Toxicol Environ Mutagen 764–765:36–45
Vasseur P, Cossu-Leguille C (2006) Linking molecular interactions to consequent effects of persistent organic pollutants (POPs) upon populations. Chemosphere 62:1033–1042
Veldhoen N, Skirrow RC, Brown LLY, Van Aggelen G, Helbing CC (2014) Effects of acute exposure to the non-steroidal anti-inflammatory drug ibuprofen on the developing North American bullfrog (Rana catesbeiana) tadpole. Environ Sci Tech 48:10439–10447
Wang CY, Ai N, Arora S, Erenrich E, Nagarajan K, Zauhar R, Young D, Welsh WJ (2006) Identification of previously unrecognized antiestrogenic chemicals using a novel virtual screening approach. Chem Res Toxicol 19:1595–1601
Watanabe KH, Andersen ME, Basu N, Carvan MJ, Crofton KM, King KA, Suñol C, Tiffany-Castiglioni E, Schultz IR (2011) Defining and modeling known adverse outcome pathways: domoic acid and neuronal signaling as a case study. Environ Toxicol Chem 30:9–21
Watson RT, Fuller M, Pokras M, Hunt WG (2009) Ingestion of lead from spent ammunition: implications for wildlife and humans. The Peregrine Fund, Boise
Weiss B (2011) Endocrine disruptors as a threat to neurological function. J Neurol Sci 305:11–21
Wellington EMH, Boxall ABA, Cross P, Feil EJ, Gaze WH, Hawkey PM, Johnson-Rollings AS, Jones DL, Lee NM, Otten W, Thomas CM, Williams AP (2013) The role of the natural environment in the emergence of antibiotic resistance in Gram-negative bacteria. Lancet Infect Dis 13:155–165
Whitehead A, Pilcher W, Champlin D, Nacci D (2012) Common mechanism underlies repeated evolution of extreme pollution tolerance. Proc R Soc B Biol Sci 279:427–433
Zoeller RT, Tan SW, Tyl RW (2007) General background on the hypothalamic-pituitary-thyroid (HPT) axis. Crit Rev Toxicol 37:11–53
Zorrilla I, Martinez R, Taggart MA, Richards N (2015) Suspected flunixin poisoning of a wild Eurasian griffon vulture from Spain. Conserv Biol 29:587–592
Zuccato E, Castiglioni S, Bagnati R, Chiabrando C, Grassi P, Fanelli R (2008) Illicit drugs, a novel group of environmental contaminants. Water Res 42:961–968
Acknowledgments
This study has been supported by the National Parks Projects [755/2012 and 768/2012] from the Spanish Ministry of the Environment.
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Mateo, R., Lacorte, S., Taggart, M.A. (2016). An Overview of Recent Trends in Wildlife Ecotoxicology. In: Mateo, R., Arroyo, B., Garcia, J. (eds) Current Trends in Wildlife Research. Wildlife Research Monographs, vol 1. Springer, Cham. https://doi.org/10.1007/978-3-319-27912-1_6
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