Abstract
When writing a study protocol, just pulling the sample size out of a hat gives rise to (1) ethical, (2) scientific, and (3) financial problems, because
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1.
too many patients may be given a potentially inferior treatment,
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2.
negative studies require repetition of the research,
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3.
costs are involved in too large or too small studies.
Equations are provided, that can be used for the purpose.
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© 2016 Springer International Publishing Switzerland
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Cleophas, T.J., Zwinderman, A.H. (2016). Sample Size Calculations. In: Clinical Data Analysis on a Pocket Calculator. Springer, Cham. https://doi.org/10.1007/978-3-319-27104-0_12
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DOI: https://doi.org/10.1007/978-3-319-27104-0_12
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Publisher Name: Springer, Cham
Print ISBN: 978-3-319-27103-3
Online ISBN: 978-3-319-27104-0
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