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Asthenia

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International Manual of Oncology Practice

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Abstract

In the era of holistic care, management of patients with malignant diseases should also embrace the effort for palliation of symptoms hampering the physical, mental and social well-being of the patient. Asthenia or cancer-related fatigue (CRF) is well acknowledged as one of the most common symptoms in cancer patients receiving anti-neoplastic therapy but also prevailing as a post-treatment remnant at the end of life, or even persisting for years in cancer survivors. It is often described as part of a symptom cluster, together with pain and depression (Laird BJ, Scott AC, Colvin LA, McKeon AL, Murray GD, Fearon KC, Fallon MT, J Pain Symptom Manage 42(1):1–11, 2011). It has been shown to have a major debilitating effect on patients’ daily routine with indirect consequences on caregivers and family members as well. Apart from the physical impairment, asthenia has also mental and emotional dimensions interfering with patients’ ability to perform activities of daily living and negatively affecting the social and economic status of the patients and their caregivers. The Fatigue-2 study demonstrated fatigue as the most prevalent symptom while receiving chemotherapy, with its impact on the patients’ quality of life (QOL) enduring longer than the effects of pain or depression (Curt GA, Oncologist 5(Suppl 2):9–12, 2000).

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  1. Hellenic Oncology Research Group, 55 Lomvardou Street, Athens, 11471, Greece

    F. Koinis & I. Gioulbasanis

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  1. Medical Oncology, University of Algarve, Faro, Portugal

    Ramon Andrade de Mello

  2. edificio 7, ala nascente, 3º andar, University of Algarve, Dept Cie Biomed edificio 7, ala nascente, 3º andar, Faro, Portugal

    Álvaro Tavares

  3. Medical Oncology, University of Athens, Athens, Greece

    Giannis Mountzios

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Koinis, F., Gioulbasanis, I. (2015). Asthenia. In: de Mello, R., Tavares, Á., Mountzios, G. (eds) International Manual of Oncology Practice. Springer, Cham. https://doi.org/10.1007/978-3-319-21683-6_38

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