Abstract
The presented work involved the design, manufacture and testing of three-dimensional scaffolds with the aim of advancing the field of bio-scaffolds from a mechanical prospective. Three different scaffold structure configurations were tested in regards to stiffness, ultimate stress and their fracture behavior. The configurations were named after the unit-cell geometry which they are based on, 0°–90° cylinder structure, 0°–90° holes in cube structure and negative body centered cubic structure (negative BCC). It could be shown that the negative BCC configuration shows the best performance with respect to the mechanical behavior under compression force.
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References
Hajar, S.: Preparation and characterization of a three-dimensional printed scaffold based on a functionalized polyester for bone tissue engineering applications. Acta Biomater. 7(5). Jan 15 2011. http://www.sciencedirect.com.libraryproxy.griffith.edu.au/science/article/pii/S1742706111000195. Accessed 3 Aug 2014
Bioscaffold Review: bioscaffold.com. 2010. http://www.bioscaffold.com. Accessed 12 Sept 2014
Williams, J.M.: Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering. Biomaterials 26, 4817–4827, January 2005. http://ac.els-cdn.com.libraryproxy.griffith.edu.au/S0142961204011068/1-s2.0-S0142961204011068-main.pdf?_tid=082f7a24-6250-11e4-a069-00000aacb361&acdnat=1414905840_21fd2922073a4e6f9113fdba78e24ee8. Accessed 11 Sept 2014
Olson, J.L. Atala, A., Yoo, J.J.: Tissue Engineering: current strategies and future directions. Chonnam Med. 47(1), 1–13, 2011. http://synapse.koreamed.org/Synapse/Data/PDFData/1057CMJ/cmj-47-1.pdf. Accessed 11 Sept 2014
Bioscaffold Review: bioscaffold.com. 2010. http://www.bioscaffold.com. Accessed 12 Sept 2014
Bio-Engineering Scaffold Tissues: isaachealthcare.net. http://www.isaachealthcare.net/?page_id=162. Accessed 10 Sept 2014
Bernd, B., Marc A.: Computational aspects of fabrication. IEEE Xplore, Published Comp. Graph. Appl IEEE 33(6), Nov–Dec, 2013. http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=6682932. Accessed 6 Aug 2014
CT Scan versus MRI: diffen.com. http://www.diffen.com/difference/CT_Scan_vs_MRI. Accessed 10 Aug 2014
Grenda, E.: Medical applications of rapid prototyping. January 2007. http://www.additive3d.com/med_lks.htm. Accessed 12 Aug 2014
Additive Fabrication: 2009. http://www.custompartnet.com/wu/additive-fabrication. Accessed 12 Aug 2014
Yen, H., Tseng, C., Hsu S., Tsai, C.: Evaluation of chondrocyte growth in the highly porous scaffolds made by fused deposition manufacturing (FDM) filled type П collagen. Biomed. Microdevices 11, 615–624, December 2008. http://link.springer.com.libraryproxy.griffith.edu.au/article/10.1007%2Fs10544-008-9271-7. Accessed 4 Aug 2014
Dao, D.: Precision Engineering & Prototyping. Lecture Notes. Rapid Prototyping & Reverse Engineering, ENG3313, School of Engineering, Griffith University, Gold Coast, (2014)
Bose, S., Vehabzadeh S., Bandyopadhyay, A.: Bone tissue engineering using 3D printing. Mater. Today 16(12), 496–504, December 2013. http://ac.els-cdn.com/S136970211300401X/1-s2.0-S136970211300401X-main.pdf?_tid=4828c698-625b-11e4-82b2-00000aacb361&acdnat=1414910672_1265a1484f587bc95051d74847f93832. Accessed 6 Aug 2014
Murphy, C.M, Haugh, M.G. O’Brien, F.J.: The effect of mean pore size on cell attachment, proliferation and migration in collagen glycosaminoglycan scaffolds for tissue engineering. Dublin, Ireland. Department of Anatomy, Royal College of Surgeons, Biomaterials. ch. 31(3), pp. 461–466 (2010)
What is 3D printing?: 3D printing experts. 2012. http://www.3d-printing-experts.com/knowledge-base/what-is-3d-printing/. Accessed 30 Oct 2014
PolyJet Technology: Stratasys, 2014. http://www.stratasys.com/3d-printers/technologies/polyjet-technology. Accessed 15 Sept 2014
VisiJet® Crystal Plastic Material: 3DSYSTEMS, Regulatory Information Sheet, June 2012. http://www.3dsystems.com/files/CIB%200912%20ProJet%20Class%20VI%20Cleaning%20VisiJet%20Crystal.pdf. Accessed 25 Sept 2014
Greaves, G.N.: Poisson’s ratio and modern materials. Nat. Mater. 10(11), 823–837, October 2011. ProQuest. http://search.proquest.com.libraryproxy.griffith.edu.au/docview/901616152?accountid=1454. Accessed 5 Oct 2014
Tensile Testing for Elastic Constants: classes.mst.edu. http://classes.mst.edu/civeng120/lessons/flexure/tension/details/index.html. Accessed 2 Nov 2014
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Hughes, G., Öchsner, A. (2015). Design, Manufacture and Testing of Three-Dimensional Scaffolds. In: Öchsner, A., Altenbach, H. (eds) Applications of Computational Tools in Biosciences and Medical Engineering. Advanced Structured Materials, vol 71. Springer, Cham. https://doi.org/10.1007/978-3-319-19470-7_9
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