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Endocrine Disorders Associated with Obesity

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Metabolic Syndrome

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Abstract

Several endocrine disorders, including diabetes, insulinoma, Cushing’s syndrome, hypothyroidism, polycystic ovarian syndrome, and growth hormone deficiency, are associated with obesity. The mechanisms for the development of obesity vary according to the primary actions of these hormones on energy balance, adipose, and other tissues. This chapter describes the pathogenesis of obesity and metabolic dysfunction associated with excess insulin or glucocorticoids and deficiency of thyroid hormone or growth hormone.

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Acknowledgments

R.S.A is supported by American Diabetes Association grant #7-13-BS-004 and National Institutes of Health grants R01-NS084965 and P01-DK049210. This work was partly supported by the Soonchunhyang University Research Fund.

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Authors and Affiliations

  1. Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, South Korea

    Hyeong-Kyu Park

  2. Division of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA

    Rexford S. Ahima

  3. Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania, Philadelphia, PA, USA

    Rexford S. Ahima

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  1. Hyeong-Kyu Park
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Correspondence to Hyeong-Kyu Park .

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  1. Division of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

    Rexford S. Ahima

  2. Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania, Philadelphia, PA, USA

    Rexford S. Ahima

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Park, HK., Ahima, R.S. (2016). Endocrine Disorders Associated with Obesity. In: Ahima, R.S. (eds) Metabolic Syndrome. Springer, Cham. https://doi.org/10.1007/978-3-319-11251-0_42

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