Abstract
The field of optical coherence tomography (OCT) has blossomed dramatically since the first studies by various researchers around the world began in the late 1980s and early 1990s. Since then cumulatively, there have been dozens of companies created, over a hundred research groups working on or with OCT, over a thousand OCT patents issued, over 10,000 research articles published, tens of millions of patients scanned with OCT, hundreds of millions of venture capital and corporate R&D dollars invested, hundreds of millions of dollars in company acquisitions, and over a billion of dollars of OCT system revenue. This chapter will describe some of the history and factors involved in OCT technology transfer and commercialization, give a snapshot of the current OCT market, and speculate on some future OCT issues.
Eric Swanson is a founder of Advanced Ophthalmic Devices (acquired by Carl Zeiss Meditec), Lightlab Imaging (acquired by St. Jude Medical), and has numerous patents that are licensed to various OCT companies. Mr. Swanson also served on the board of NinePoint Medical Imaging and several other high-tech companies.
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Notes
- 1.
In this analysis, only title and abstract were considered. The result is that this data probably underestimates the number of OCT publications but is a good bound. Another limitation is it can be difficult to categorize a publication into a particular subject area, and often publications are in multiple subject areas, and it is often a blurry call if the paper is about fundamental technology or about an application of the technology. Note this data is based on the PubMed database has many good attributes, but there are also limitations in that it doesn’t cover every journal, and the number of journals it covers has increased over time.
- 2.
In the United States, the Bayh-Dole Act states that universities need to share royalties with the inventor.
- 3.
Patent troll is a derogatory term for a company that creates or acquires patents and often use what some feel are unsavory tactics against alleged infringers in a manner that is aggressive and often they have no intention to produce any products of their own.
- 4.
The Canadian data is from the combined Canadian funding from Natural Sciences and Engineering Research Council (NSERC), Canadian Institutes of Health Research (CIHR), and National Cancer Institute of Canada (NCIC). The UK data is combined UK funding from Engineering and Physical Sciences Research Council (EPSRC), Biotechnology and Biological Science Research Council (BBSRC), and Medical Research Council (MRC).
- 5.
There are other OCT companies that currently exist or started in this time period but are not listed here due to their small scale and/or company status or desire to remain confidential.
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Acknowledgements
I would like to thank the following people for helpful discussion and contributions to this chapter. James Fujimoto, Joseph Schmitt, Jay Wei, Chris Petersen, David Huang, Jack Turner, Maciej Wojtkowski, Wolfgang Drexler, Peter Norris, Bertrand Le Conte de Poly, Lori Pressman, Eric Buckland, Rainer Nebosis, Brian Courtney, Masataka Tei, Ralph Johnston, Chris Ritter, Charles Carignan, Ewa Mentel, Gaku Takeuchi, Adam Wax, Arjun Desai, Sabrrina Klinkert, Jim Fulton, Michael Kempe, Jon Holmes, Frederic Sweeny, Eduardo Margallo, and Aaron Aguirre.
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Appendix: Examples of Existing OCT Commercial Products
Appendix: Examples of Existing OCT Commercial Products
Below are some representative examples of existing OCT commercial products. There are more OCT system products on the market than those listed here, and several of the companies listed have multiple products.
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Swanson, E.A. (2015). OCT Technology Transfer and the OCT Market. In: Drexler, W., Fujimoto, J. (eds) Optical Coherence Tomography. Springer, Cham. https://doi.org/10.1007/978-3-319-06419-2_86
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