Abstract
The development of corneal and anterior segment optical coherence tomography (OCT) technology has advanced rapidly in recently years. The scan geometry and imaging wavelength are both important choices to make in designing anterior segment OCT systems. Rectangular scan geometry offers the least image distortion and is now used in most anterior OCT systems. The wavelength of OCT light source affects resolution and penetration. An optimal choice of the OCT imaging wavelength (840, 1,050, or 1,310 nm) depends on the application of interest. Newer generation Fourier-domain OCT technology can provide scan speed 100–1000 times faster than the time-domain technology. Various commercial anterior OCT systems are available on the market. A wide spectrum of diagnostic and surgical applications using anterior segment OCT had been investigated, including mapping of corneal and epithelial thicknesses, keratoconus screening, measuring corneal refractive power, corneal surgery planning and evaluation in LASIK, intracorneal ring implantation, assessment of angle closure glaucoma, anterior chamber biometry and intraocular lens implants, intraocular lens power calculation, and eye bank donor cornea screening.
Proprietary Interests: David Huang and Yan Li have significant financial interests in Optovue and Carl Zeiss Meditec, companies that may have a commercial interest in the results of this research and technology. Maolong Tang has a significant financial interest in Optovue. These potential conflicts of interest have been reviewed and managed by Oregon Health and Science University.
Financial Support: this study was supported by NIH grants R01 EY018184, a grant from Optovue Inc. and a grant from Research to Prevent Blindness, Inc.
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Huang, D., Li, Y., Tang, M. (2015). Anterior Eye Imaging with Optical Coherence Tomography. In: Drexler, W., Fujimoto, J. (eds) Optical Coherence Tomography. Springer, Cham. https://doi.org/10.1007/978-3-319-06419-2_57
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