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Precision Medicine

  • Book
  • © 2023

Overview

Editors:
  1. Ingolf Cascorbi

    1. Institute of Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Kiel, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Matthias Schwab

    1. Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany

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    You can also search for this editor in PubMed   Google Scholar

  • Comprehensive summary of applications of precision medicine in clinical practice
  • State-of-the art techniques in precision medicine
  • Implementation of pharmacogenomics

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 280)

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About this book

The rapidly increased understanding of the molecular background of complex diseases facilitated the development of highly advanced therapeutic concepts. Such concepts aiming to consider individual signatures of genomic and proteomic biomarkers including pharmacogenomics as well as advanced diagnostic tools have been successfully implemented in clinical practice in various fields leading to significant improvement of treatment successes. This volume gives an up-to-date overview on applications of precision medicine in various clinical entities, on advanced techniques as well as on economic considerations.

Keywords

Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
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  2. Pharmacogenomics

    1. Front Matter

      Pages 1-1
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    2. The Implementation of Pharmacogenetics in the United Kingdom

      • John H. McDermott, Videha Sharma, Jessica Keen, William G. Newman, Munir Pirmohamed
      Pages 3-32

  3. Precision Medicine in Clinical Entities

    1. Front Matter

      Pages 33-33
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    2. Precision Medicine in Therapy of Non-solid Cancer

      • Ines Schmidts, Torsten Haferlach, Gregor Hoermann
      Pages 35-64

    3. Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia

      • Meike Kaehler, Ingolf Cascorbi
      Pages 65-83

    4. Precision Medicine in Asthma Therapy

      • Stefania Principe, Susanne J. H. Vijverberg, Mahmoud I. Abdel-Aziz, Nicola Scichilone, Anke H. Maitland-van der Zee
      Pages 85-106

    5. Precision Medicine in Diabetes

      • Adem Y. Dawed, Eram Haider, Ewan R. Pearson
      Pages 107-129

    6. Precision Medicine in Antidepressants Treatment

      • Evangelia Eirini Tsermpini, Alessandro Serretti, Vita Dolžan
      Pages 131-186

    7. Precision Medicine in Neuropathic Pain

      • Juliane Sachau, Ralf Baron
      Pages 187-210

  4. Techniques in Precision Medicine

    1. Front Matter

      Pages 211-211
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    2. Imaging Techniques in Pharmacological Precision Medicine

      • Lucas Freidel, Sixing Li, Anais Choffart, Laura Kuebler, André F. Martins
      Pages 213-235

    3. Challenges Related to the Use of Next-Generation Sequencing for the Optimization of Drug Therapy

      • Yitian Zhou, Volker M. Lauschke
      Pages 237-260

  5. Economics

    1. Front Matter

      Pages 261-261
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    2. Economics and Precision Medicine

      • Katherine Payne, Sean P. Gavan
      Pages 263-281

    3. Correction to: Precision Medicine in Antidepressants Treatment

      • Evangelia Eirini Tsermpini, Alessandro Serretti, Vita Dolžan
      Pages 283-283
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Editors and Affiliations

  • Institute of Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Kiel, Germany

    Ingolf Cascorbi

  • Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany

    Matthias Schwab

Bibliographic Information

  • Book Title: Precision Medicine

  • Editors: Ingolf Cascorbi, Matthias Schwab

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-031-40047-6

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023

  • Hardcover ISBN: 978-3-031-40046-9Published: 02 September 2023

  • Softcover ISBN: 978-3-031-40049-0Due: 03 October 2023

  • eBook ISBN: 978-3-031-40047-6Published: 01 September 2023

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: X, 283

  • Number of Illustrations: 70 b/w illustrations, 30 illustrations in colour

  • Topics: Pharmacology/Toxicology, Internal Medicine, Cancer Research

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