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Visceral Pain

  • Book
  • © 2023

Overview

Editors:
  1. Stuart M. Brierley

    1. Visceral Pain Research Group, Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, Australia

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  2. Nick J. Spencer

    1. Visceral Neurophysiology Laboratory, College of Medicine and Public Health & Flinders Health and Medical Research Institute, Flinders University, Bedford Park, Australia

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  • Presents the latest research on visceral pain
  • Features contributions from preeminent researchers in the fields of the enteric nervous system and visceral pain
  • Covers hot topics such as the microbiome and gut-brain axis, and optogenetic probing of nociceptive pathways

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-viii
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  2. In Vivo Non-linear Optical Microscopy as a Multidimensional Approach to Decipher Sensory Coding

    • Feng Wang, Yves De Koninck
    Pages 1-15

  3. An Open Science Model to Accelerate the Generation, Implementation and Distribution of Optogenetics and Viral Tools

    • Marie-Eve Paquet, Yves De Koninck
    Pages 17-26

  4. Vagal Neuroinflammation Accompanying Respiratory Viral Infection: An Overview of Mechanisms and Possible Clinical Significance

    • Nathalie A. J. Verzele, Kirsty R. Short, Stuart B. Mazzone, Alice E. McGovern
    Pages 27-41

  5. Stress-Induced Visceral Analgesia: Concept and Pathways

    • Muriel Larauche
    Pages 43-53

  6. Evidence of Early Life Stress Exposure and Epigenetic Modifications in Functional Chronic Pain Disorders

    • Brittni M. Levasseur, Erin E. Young, Julie A. Christianson
    Pages 55-69

  7. Epigenetic Regulation of Stress-Induced Visceral Pain

    • Tijs Louwies
    Pages 71-80

  8. The Biomechanics of Distal Colon and Rectum and Its Relevance to Visceral Pain

    • Bin Feng, David M. Pierce
    Pages 81-103

  9. Visceral Nociception in Gastrointestinal Disease

    • James Higham, Rohit Gupta, David C. Bulmer
    Pages 105-116

  10. Epithelial-Neuronal Communication in Visceral Pain

    • Sarah A. Najjar
    Pages 117-128

  11. Physiological Mechanisms Underpinning Heightened Perception of Visceral Afferent Signalling in Irritable Bowel Syndrome

    • Dervla O’Malley
    Pages 129-142

  12. A Fentanyl Analogue That Activates u-Opioid Receptors in Acidified Tissues Inhibits Colitis Pain without Opioid Side Effects

    • Nestor N. Jimenez-Vargas, Claudius E. Degro, Christoph Stein, Nigel W. Bunnett, Stephen J. Vanner
    Pages 143-152

  13. Signalling in the Gut

    • Friederike Uhlig, David Grundy
    Pages 153-160

  14. Translating Colonic Sensory Afferent Peripheral Mechanosensitivity into the Spinal Cord Dorsal Horn

    • Andrea M. Harrington
    Pages 161-181

  15. Mechanisms of Spinal Cord Plasticity in Rodent Models of Acute and Post-Colitis Visceral Hypersensitivity

    • Andrea M. Harrington
    Pages 183-196

  16. Neuron-Microglia Dynamic Duo in Chronic Abdominal Pain

    • Manon Defaye, Christophe Altier
    Pages 197-207

  17. Pre-clinical Models of Endometriosis: A Focus on Chronic Pain

    • Jessica Maddern, Stuart M. Brierley, Joel Castro
    Pages 209-222

  18. Spinal Afferent Innervation of the Uterus

    • Kelsi N. Dodds, Nick J. Spencer
    Pages 223-234

  19. Post-Infectious Bladder Hypersensitivity in the Development of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

    • Harman Sharma, Georgia Bourlotous, Luke Grundy
    Pages 235-251

  20. Back Matter

    Pages 253-255
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Keywords

About this book

The chapters in this book are based on the Visceral Pain conference in Adelaide, Australia, under the auspices of the International Federation for Neurogastroenterology and Motility in 2021. This is one of the hottest fields of science and includes mechanisms involving how the microbiome communicates with the brain and how, when disordered, these mechanisms contribute to clinical diseases such as Irritable Bowel Syndrome and Inflammatory Bowel Disease. Researchers from around the globe presented their latest findings as a review of the current state of the art in the field from both the clinical and scientific points of view. These systems are now appreciated as being critical for shaping our well-being and their disorders underlie chronic clinical conditions of significant morbidity and mortality. The author team includes long-established authorities who significantly contributed to the advances in visceral pain research over the past two decades and the new generation thatwill continue to contribute to advancing our understanding of the field.

Editors and Affiliations

  • Visceral Pain Research Group, Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, Australia

    Stuart M. Brierley

  • Visceral Neurophysiology Laboratory, College of Medicine and Public Health & Flinders Health and Medical Research Institute, Flinders University, Bedford Park, Australia

    Nick J. Spencer

About the editors

Dr. Stuart Brierley, PhD, is a Matthew Flinders Professor in Gastrointestinal Neuroscience, a NHMRC Investigator Leadership Fellow and Director of the Visceral Pain Research Group at Flinders University in Adelaide, South Australia. He is also Director of the Hopwood Centre for Neurobiology and co-lead of the Lifelong Health Theme at the South Australian Health & Medical Research Institute in Adelaide.

 

Dr. Nick Spencer, PhD is a Mathew Flinders Professor of Neurophysiology at Flinders Medical Centre in Adelaide, South Australia.


Bibliographic Information

  • Book Title: Visceral Pain

  • Editors: Stuart M. Brierley, Nick J. Spencer

  • DOI: https://doi.org/10.1007/978-3-031-25702-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023

  • Hardcover ISBN: 978-3-031-25701-8Published: 24 March 2023

  • Softcover ISBN: 978-3-031-25704-9Published: 25 March 2024

  • eBook ISBN: 978-3-031-25702-5Published: 23 March 2023

  • Edition Number: 1

  • Number of Pages: VIII, 255

  • Number of Illustrations: 4 b/w illustrations, 33 illustrations in colour

  • Topics: Neurosciences, Physiology, Gastroenterology

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