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Evaluation of the Efficacy of Pharmacotherapy for Decompensated Intestinal Dysbacteriosis in Cats

  • Conference paper
  • First Online:
XV International Scientific Conference “INTERAGROMASH 2022” (INTERAGROMASH 2022)

Part of the book series: Lecture Notes in Networks and Systems ((LNNS,volume 575))

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Abstract

The treatment of intestinal dysbiosis in animals remains one of the most complex and urgent problems in veterinary medicine to this day. Recently, a steady increase in pathologies has been recorded, accompanied by the development of disorders of the gastrointestinal tract of various etiologies in animals. Despite the constant improvement of methods for correcting the intestinal microbiota, the occurrence of dysbacteriosis in various pathological processes not only does not decrease, but, on the contrary, increases. Therefore, the choice of the optimal therapeutic regimen for the correction of the most severe decompensated degree of intestinal dysbacteriosis in cats is an important area of scientific research. The article shows that in case of decompensated intestinal dysbacteriosis in cats, the administration of the probiotic “Lactobifadol” in combination with the prebiotic “Vetelact” and the immunomodulator “Azoksivet” against the background of infusion therapy is the most effective, as evidenced by the registration of an overall clinical improvement of 1.28 times (p < 0.001) faster, when compared with animals of the group C1. At the same time, normalization of appetite, unpleasant odor from the oral cavity and the nature of fecal matter occurs in cats of group C3 1.40 days (p < 0.05), 1.60 days (p < 0.01) and 1.80 days (p < 0.01) earlier, according to compared with animals that were corrected according to scheme C1.

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Author information

Authors and Affiliations

  1. Branch of Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences (BIBCh RAS), Avenue Science, 6, 142290, Pushchino, Russia

    Pavel Rudenko

  2. Moscow State Academy of Veterinary Medicine and Biotechnology–MVA by K.I. Scryabin, Academician Skryabin Street 23, 109472, Moscow, Russia

    Pavel Rudenko

  3. Department of Veterinary Medicine, Peoples’ Friendship University of Russia, Miklukho-Maklaya Street, 6, 117198, Moscow, Russia

    Nikolay Bugrov

  4. Don State Technical University, Sq. Gagarin, 1, 344003, Rostov-on-Don, Russia

    Sergey Tresnitskiy

  5. Moscow State University of Food Production, Volokolamskoe Shosse, 11, 125080, Moscow, Russia

    Ekaterina Lenchenko, Yulia Subbotina & Dmitry Blumenkrants

Authors
  1. Pavel Rudenko
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  2. Nikolay Bugrov
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  3. Sergey Tresnitskiy
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  4. Ekaterina Lenchenko
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  5. Yulia Subbotina
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  6. Dmitry Blumenkrants
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Corresponding author

Correspondence to Sergey Tresnitskiy .

Editor information

Editors and Affiliations

  1. Don State Technical University, Rostov- on-Don, Russia

    Alexey Beskopylny

  2. Saint Petersburg State Institute of Technology, Saint Petersburg, Russia

    Mark Shamtsyan

  3. Petet the Great St.Petersburg State Polytechnic University, Saint Petersburg, Russia

    Viktor Artiukh

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Rudenko, P., Bugrov, N., Tresnitskiy, S., Lenchenko, E., Subbotina, Y., Blumenkrants, D. (2023). Evaluation of the Efficacy of Pharmacotherapy for Decompensated Intestinal Dysbacteriosis in Cats. In: Beskopylny, A., Shamtsyan, M., Artiukh, V. (eds) XV International Scientific Conference “INTERAGROMASH 2022”. INTERAGROMASH 2022. Lecture Notes in Networks and Systems, vol 575. Springer, Cham. https://doi.org/10.1007/978-3-031-21219-2_68

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  • DOI: https://doi.org/10.1007/978-3-031-21219-2_68

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-21218-5

  • Online ISBN: 978-3-031-21219-2

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