Abstract
Monitoring glucose levels is a very important task in diabetic patients to avoid health complications. Sensors for sweat glucose detection are a promising tool as a non-invasive method to quantify glucose concentration. However, due to the low glucose concentration, sensing based on sweat remains a challenge for low-cost, simple, and affordable devices. Thus, this work introduces a resistive paper-based sensor for sensing glucose in sweat using the molecularly imprinted polymer (MIP) method, which allows to create specific molecular templates for target detection. Our sensor is based on MIP over eco-friendly paper strips and screen-printed electrodes, coupled with a simple read-out hardware for wireless data streaming, ideal for wearable devices. We show the sensor fabrication stage and characterization tests in glucose levels from 0 to 80 \(\mu \)M, achieving a detection limit of 4.2 \(\mu \)M. The results show that our sensor is a low-cost and attractive alternative towards a sweat glucose wearable sensor, with high reliability, low detection limit, and easy fabrication process.
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Acknowledgments
Bryan E. Alvarez-Serna acknowledges CONACYT for the Ph.D. studies grant (CVU 1004078). This work was supported by the grants DGAPA-UNAM PAPIIT TA100221 and PAPIME PE101222.
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Alvarez-Serna, B.E., Balderas-Zempoaltecaltl, Ae., Ramírez-Chavarría, R.G. (2023). Molecularly Imprinted Polymer Paper-Based Biosensor for Wireless Measurement of Sweat Glucose. In: Trujillo-Romero, C.J., et al. XLV Mexican Conference on Biomedical Engineering. CNIB 2022. IFMBE Proceedings, vol 86. Springer, Cham. https://doi.org/10.1007/978-3-031-18256-3_64
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DOI: https://doi.org/10.1007/978-3-031-18256-3_64
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