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Natural Products in Controlling and Treatment of Cancers and Genital Warts Caused by Different Viruses

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Anti-Viral Metabolites from Medicinal Plants

Part of the book series: Reference Series in Phytochemistry ((RSP))

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Abstract

Cancer is a disease characterized by uncontrolled cell division and fast metastasis to various body parts. Cancer is the leading global threat affecting a large population. By the year-end of 2050, almost 27 million people will be affected by cancer and the annual mortality is to be approximately 17 million. In the treatment of different types of cancers: curcumin, gingerol, piperine, sanguinarine, and daidzin; nimbolide, curcumin, berberine, triptolide, and baicalein; berbamine, berberine, Lirioresinol B dimethyl ether, aconitine, and oxymatrine; paclitaxel, glycyrrhizic acid, michellamines, and coumarin; cepharanthine, arctigenin; and cryptolepine, podophyllotoxin, and podophyllin showed effective outcomes. Adjuvant treatment of natural products with current regimens could be beneficial in multiple aspects, including reducing adverse effect, overcoming drug resistance, and improving the therapeutic response.

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Abbreviations

AIDS:

Acquired Immunodeficiency Syndrome

Akt:

Protein Kinase B

BP:

N-butylidenephthalide

DNA:

Deoxyribonucleic acid

EBNA1:

Epstein Barr Virus encoded Nuclear Antigen 1

EBV:

Epstein-Barr Virus

GBM:

Glioblastoma Multiforme

HBV:

Hepatitis B Virus

HCC:

Hepatocellular Carcinoma

HCV:

Hepatitis C Virus

HIV:

Human Immunodeficiency Virus

HONE-1:

Epithelial Tumor Cell line

HPV:

Human Papilloma Virus

iNOS:

Inducible Nitric Oxide Synthase

MCC:

Merkel Cell Carcinoma

NPC-039:

Cellosaurus Cell line

PI3K:

Phosphoinositide 3- Kinase

RNA:

Ribonucleic Acid

ROS:

Reactive Oxygen Species

TNF:

Tumor Necrosis Factor

XIAP:

X-linked inhibitor of apoptosis protein

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Author information

Authors and Affiliations

  1. Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, Uttarakhand, India

    Supriyo Saha

  2. Department of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, India

    Dilipkumar Pal

  3. School of Pharmaceutical Sciences, Himgiri Zee University, Dehradun, Uttarakhand, India

    Riya Mahar

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  1. Supriyo Saha
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  2. Riya Mahar
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  3. Dilipkumar Pal
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Editors and Affiliations

  1. Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur, India

    Dilipkumar Pal

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Saha, S., Mahar, R., Pal, D. (2023). Natural Products in Controlling and Treatment of Cancers and Genital Warts Caused by Different Viruses. In: Pal, D. (eds) Anti-Viral Metabolites from Medicinal Plants. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-030-83350-3_24-1

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  • DOI: https://doi.org/10.1007/978-3-030-83350-3_24-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-83350-3

  • Online ISBN: 978-3-030-83350-3

  • eBook Packages: Springer Reference Chemistry and Mat. ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics

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