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A Global Perspective of Cancer Prevalence: The Causative Agent, the Environment, or the Genes?

  • Living reference work entry
  • First Online:
Handbook of Cancer and Immunology

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Abstract

Cancer is among the most leading causes of death worldwide, while breast and prostate cancers are the leading causes of cancers among females and males, respectively. Other cancers like lung cancer, cervix cancer, colorectal cancer, liver cancer, lip and oral cancer, stomach cancer and esophageal cancers are the leading causes of cancer in specific regions.

Since the discovery of cancer, the interplay between genetic and environmental factors is known as the major etiology of cancer. The variety of the prevalence of cancers in discrete regions of the world strengthens the possibility of the existence of both lifestyle and ethnical portions in the pathophysiology of diverse cancers.

In this chapter, an extensive investigation of both the genetic and the environmental factors influencing the incidence of diverse cancers globally is conducted in this chapter.

Knowing the etiological agents can play a role in tailoring personalized strategies for curbing the incidence of cancer worldwide before.

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References

  • Addula D, Das CJ, Kundra V (2021) Imaging of Kaposi sarcoma. Abdominal Radiol (New York) 46(11):5297–5306, Springer

    Article  Google Scholar 

  • Adeloye D et al (2016) An estimate of the incidence of prostate cancer in Africa: a systematic review and meta-analysis. PLoS One 11(4):e0153496

    Article  PubMed  PubMed Central  Google Scholar 

  • Al Qadire M, Alkhalaileh M, ALBashtawy M (2019) Lifestyle and dietary factors and prostate cancer risk: a multicentre case-control study. Clin Nurs Res 28(8):992–1008

    Article  PubMed  Google Scholar 

  • Alam MS et al (2021) Rapid rise of life expectancy in Bangladesh: does financial development matter? Int J Finance Econ 26(4):4918–4931, John Wiley & Sons, Ltd.

    Article  Google Scholar 

  • Al-Elq AH (2012) The status of vitamin D in medical students in the pre-clerkship years of a Saudi medical school. J Fam Community Med. ncbi.nlm.nih.gov. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3410172/

  • Allende G et al (2020) Evaluation of the effectiveness of high-risk human papilloma self-sampling test for cervical cancer screening in Bolivia. BMC Infect Dis 20(1):259

    Article  PubMed  PubMed Central  Google Scholar 

  • Almatroudi A (2020) The incidence rate of colorectal cancer in Saudi Arabia: an observational descriptive epidemiological analysis. Int J General Med. ncbi.nlm.nih.gov. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7605625/

  • Alsheridah N, Akhtar S (2018) Diet, obesity and colorectal carcinoma risk: results from a national cancer registry-based middle-eastern study. BMC Cancer 18(1):1227

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ambros V (2003) MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell 113(6):673–676

    Article  CAS  PubMed  Google Scholar 

  • Aune D et al (2015) Dairy products, calcium, and prostate cancer risk: a systematic review and meta-analysis of cohort studies. Am J Clin Nutr 101(1):87–117

    Article  CAS  PubMed  Google Scholar 

  • Aupérin A (2020) Epidemiology of head and neck cancers: an update. Curr Opin Oncol 32(3):178–186

    Article  PubMed  Google Scholar 

  • Baatarkhuu O et al (2008) Prevalence and genotype distribution of hepatitis C virus among apparently healthy individuals in Mongolia: a population-based nationwide study. Liver Int 28(10):1389–1395

    Article  PubMed  Google Scholar 

  • Baatarkhuu O et al (2017) Viral hepatitis and liver diseases in Mongolia. Euroasian J Hepato-gastroenterol 7(1):68–72

    Article  Google Scholar 

  • Baatarkhuu O et al (2018) Epidemiology, genotype distribution, prognosis, control, and management of viral hepatitis B, C, D, and hepatocellular carcinoma in Mongolia. Euroasian J Hepato-gastroenterol 8(1):57–62

    Article  Google Scholar 

  • Bahnassy AA, Abdellateif MS, Zekri A-RN (2020) Cancer in Africa: is it a genetic or environmental health problem? Front Oncol 10:604214

    Article  PubMed  PubMed Central  Google Scholar 

  • Barrington WE et al (2015) Difference in Association of Obesity with Prostate Cancer Risk between US African American and non-hispanic White men in the selenium and vitamin E cancer prevention trial (SELECT). JAMA Oncol 1(3):342–349

    Article  PubMed  PubMed Central  Google Scholar 

  • Bell DW et al (2005) Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR. Nat Genet 37(12):1315–1316

    Article  CAS  PubMed  Google Scholar 

  • Birnbaum J et al (2016) The effect of treatment advances on the mortality results of breast cancer screening trials: a microsimulation model. Ann Intern Med 164(4):236–243

    Article  PubMed  PubMed Central  Google Scholar 

  • Blumenthal MJ et al (2018) EPHA2 sequence variants are associated with susceptibility to Kaposi’s sarcoma-associated herpesvirus infection and Kaposi’s sarcoma prevalence in HIV-infected patients. Cancer Epidemiol 56:133–139, Elsevier BV

    Article  PubMed  PubMed Central  Google Scholar 

  • Blumenthal MJ et al (2021) Evidence for altered host genetic factors in KSHV infection and KSHV-related disease development. Rev Med Virol 31(2):e2160, Wiley

    Article  CAS  PubMed  Google Scholar 

  • Byakodi R et al (2012) Oral cancer in India: an epidemiologic and clinical review. J Community Health 37(2):316–319

    Article  Google Scholar 

  • Carcas LP (2014) Gastric cancer review. J Carcinogenesis 13:14

    Article  Google Scholar 

  • Cesarman E et al (2019) Kaposi sarcoma. Nat Rev Dis Primers 5(1):9, nature.com

    Article  PubMed  PubMed Central  Google Scholar 

  • Chaabna K et al (2021) Prevalence and genotype distribution of hepatitis C virus in Mongolia: systematic review and meta-analysis. Int J Infect Dis 105:377–388

    Article  CAS  PubMed  Google Scholar 

  • Chakraborty R, Roy S (2018) Exploration of the diversity and associated health benefits of traditional pickles from the Himalayan and adjacent hilly regions of Indian subcontinent. J Food Sci Technol 55(5):1599–1613

    Article  PubMed  PubMed Central  Google Scholar 

  • Chakravorty NNT (2018) The development surprise of Bangladesh: its implications for other Bay-of-Bengal and Andaman Sea Rim Nations. South Asian Survey 25(1–2):1–26, SAGE Publications India

    Article  Google Scholar 

  • Chu LW et al (2011) Prostate cancer incidence rates in Africa. Prostate cancer 2011:947870

    Article  PubMed  PubMed Central  Google Scholar 

  • Cook MB, Chow W-H, Devesa SS (2009) Oesophageal cancer incidence in the United States by race, sex, and histologic type, 1977–2005. Br J Cancer 101(5):855–859

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Crew KD, Neugut AI (2006) Epidemiology of gastric cancer. World J Gastroenterol: WJG 12(3):354–362

    Article  PubMed  PubMed Central  Google Scholar 

  • Daniyal M et al (2015) Risk factors and epidemiology of gastric cancer in Pakistan. Asian Pacific journal of cancer prevention: APJCP 16(12):4821–4824

    Article  PubMed  Google Scholar 

  • Dashtseren B et al (2017) Endemic prevalence of hepatitis B and C in Mongolia: a nationwide survey amongst Mongolian adults. J Viral Hepat 24(9):759–767

    Article  CAS  PubMed  Google Scholar 

  • Denny L et al (2014) Human papillomavirus prevalence and type distribution in invasive cervical cancer in sub-Saharan Africa. Int J Cancer 134(6):1389–1398, Wiley

    Article  CAS  PubMed  Google Scholar 

  • Didkowska J et al (2016) Lung cancer epidemiology: contemporary and future challenges worldwide. Ann Transl Med 4(8):150

    Article  PubMed  PubMed Central  Google Scholar 

  • Dondog B et al (2011) Hepatitis B and C virus infections in hepatocellular carcinoma and cirrhosis in Mongolia. Eur J Cancer Prev 20(1):33–39

    Article  CAS  PubMed  Google Scholar 

  • Faguet GB (2015) A brief history of cancer: age-old milestones underlying our current knowledge database. Int J Cancer 136(9):2022–2036

    Article  CAS  PubMed  Google Scholar 

  • Fayadh MH, Sabih SA, Quadri HA (2019) 8 years observational study on colorectal cancer in UAE. J Coloproctology (Rio de Janeiro) 39(4):394–395. Sociedade Brasileira de Coloproctologia

    Article  Google Scholar 

  • Feng Y et al (2018) Breast cancer development and progression: risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis. Genes Dis 5(2):77–106

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ferlay J, Siegel RL, Laversanne M (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. Wiley Online Library. Available at: https://acsjournals.onlinelibrary.wiley.com/doi/abs/10.3322/caac.21660

  • Ferlay J et al (n.d.) GLOBOCAN 2012: estimated cancer incidence, mortality and prevalence worldwide in 2012 v1.0

    Google Scholar 

  • Ferrís-I-Tortajada J et al (2011) Non dietetic environmental risk factors in prostate cancer. Actas urologicas espanolas 35(5):289–295

    PubMed  PubMed Central  Google Scholar 

  • Ferro A et al (2014) Worldwide trends in gastric cancer mortality (1980–2011), with predictions to 2015, and incidence by subtype. Eur J Cancer 50(7):1330–1344

    Article  PubMed  Google Scholar 

  • Freedman ND et al (2010) Male predominance of upper gastrointestinal adenocarcinoma cannot be explained by differences in tobacco smoking in men versus women. Eur J Cancer 46(13):2473–2478

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ghantous Y, Abu Elnaaj I (2017) Global incidence and risk factors of oral cancer. Harefuah 156(10):645–649

    PubMed  Google Scholar 

  • Giri VN, Hyatt C, Gomella LG (2019) Germline testing for men with prostate cancer: navigating an expanding new world of genetic evaluation for precision therapy and precision management. J Clin Oncol 37(17):1455–1459

    Article  CAS  Google Scholar 

  • Gomez JM, Wang AY (2014) Gastric intestinal metaplasia and early gastric cancer in the west: a changing paradigm. Gastroenterol Hepatol 10(6):369–378

    Google Scholar 

  • Gómez-Acebo I et al (2017) Risk model for prostate cancer using environmental and genetic factors in the Spanish Multi-Case-Control (MCC) study. Sci Rep 7(1):8994

    Article  PubMed  PubMed Central  Google Scholar 

  • Guha N et al (2014) Betel quid chewing and the risk of oral and oropharyngeal cancers: a meta-analysis with implications for cancer control. Int J Cancer 135(6):1433–1443

    Article  CAS  PubMed  Google Scholar 

  • Guraya SY (2018) The prevalence and evolving risk factors for colorectal cancer in the Arab world. Biomed Pharmacol J 11(4):1773–1780

    Article  CAS  Google Scholar 

  • Guraya SY, Eltinay OE (2006) Higher prevalence in young population and rightward shift of colorectal carcinoma. Saudi Med J 27(9):1391–1393

    PubMed  Google Scholar 

  • Hajizadeh N et al (2017) Bayesian adjustment for over-estimation and under-estimation of gastric cancer incidence across Iranian provinces. World J Gastrointestinal Oncol 9(2):87–93

    Article  Google Scholar 

  • Hamdi Y et al (2021) Cancer in Africa: the untold story. Front Oncol 11:650117

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hatta MNA et al (2021) Pathogens and carcinogenesis: a review. Biology 10(6). https://doi.org/10.3390/biology10060533

  • Heck JE et al (2012) Betel quid chewing in rural Bangladesh: prevalence, predictors and relationship to blood pressure. Int J Epidemiol 41(2):462–471

    Article  PubMed  Google Scholar 

  • Heidrich B, Manns MP, Wedemeyer H (2013) Treatment options for hepatitis delta virus infection. Curr Infect Dis Rep 15(1):31–38

    Article  PubMed  Google Scholar 

  • Hong Y et al (2005) The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma. Cancer Res 65(20):9582–9587

    Article  CAS  PubMed  Google Scholar 

  • Hongo M, Nagasaki Y, Shoji T (2009) Epidemiology of esophageal cancer: orient to occident. Effects of chronology, geography, and ethnicity. J Gastroenterol Hepatol 24(5):729–735

    Article  PubMed  Google Scholar 

  • Hosgood HD 3rd et al (2015) Interactions between household air pollution and GWAS-identified lung cancer susceptibility markers in the female lung cancer consortium in Asia (FLCCA). Hum Genet 134(3):333–341

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Huang G-L et al (2009) Clinical significance of miR-21 expression in breast cancer: SYBR-green I-based real-time RT-PCR study of invasive ductal carcinoma. Oncol Rep 21(3):673–679

    CAS  PubMed  Google Scholar 

  • Huang J et al (2021) Global burden, risk factors, and trends of esophageal cancer: an analysis of cancer registries from 48 countries. Cancers 13(1). https://doi.org/10.3390/cancers13010141

  • Hughes SA, Wedemeyer H, Harrison PM (2011) Hepatitis delta virus. Lancet 378(9785):73–85

    Article  PubMed  Google Scholar 

  • Hurst R et al (2012) Selenium and prostate cancer: systematic review and meta-analysis. Am J Clin Nutr 96(1):111–122

    Article  CAS  PubMed  Google Scholar 

  • Hussain AN et al (2014) Increasing trends and significance of hypovitaminosis D: a population-based study in the Kingdom of Saudi Arabia. Arch Osteoporos 9:190

    Article  PubMed  Google Scholar 

  • Hussein NR (2010) Helicobacter pylori and gastric cancer in the Middle East: a new enigma? World J Gastroenterol: WJG 16(26):3226–3234

    Article  PubMed  PubMed Central  Google Scholar 

  • IARC (2021) Cancer incidence in five continents. World Health Organization

    Google Scholar 

  • IARC (2022) CI5 I-X – table, cancer incidence in five continents Volumes I to X. Available at: https://ci5.iarc.fr/CI5I-X/Pages/table3_sel.aspx. Accessed: 2022

  • Janssen-Heijnen MLG, Coebergh J-WW (2003) The changing epidemiology of lung cancer in Europe. Lung Cancer 41(3):245–258

    Article  PubMed  Google Scholar 

  • Jazag A, Puntsagdulam N, Chinburen J (2012) Status quo of chronic liver diseases, including hepatocellular carcinoma, in Mongolia. Korean J Intern Med 27(2):121–127

    Article  PubMed  PubMed Central  Google Scholar 

  • Joya M et al (2020) Prevalence of cancers diagnosed in Jamhuriyat Hospital, Kabul, Afghanistan. Heliyon 6(3):e03603

    Article  PubMed  PubMed Central  Google Scholar 

  • Kamyab K et al (2014) Demographic and histopathologic study of Kaposi’s sarcoma in a dermatology clinic in the years of 2006 to 2011. Acta Med Iran 52(5):381–384, Acta.tums.ac.ir

    PubMed  Google Scholar 

  • Kanwal M, Ding X-J, Cao Y (2017) Familial risk for lung cancer. Oncol Lett 13(2):535–542

    Article  CAS  PubMed  Google Scholar 

  • Kheirelseid EHA et al (2011) Younger age as a prognostic indicator in breast cancer: a cohort study. BMC Cancer 11:383

    Article  PubMed  Google Scholar 

  • Krown SE (2011) Treatment strategies for Kaposi sarcoma in sub-Saharan Africa: challenges and opportunities. Curr Opin Oncol 23(5):463–468. Ovid Technologies (Wolters Kluwer Health)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Li X, Hemminki K (2004) Inherited predisposition to early-onset lung cancer according to histological type. Int J Cancer 112(3):451–457

    Article  CAS  PubMed  Google Scholar 

  • Lidenge SJ et al (2020) Comparative transcriptome analysis of endemic and epidemic Kaposi’s sarcoma (KS) lesions and the secondary role of HIV-1 in KS pathogenesis. PLoS Pathog 16(7):e1008681. journals.plos.org

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lillberg K et al (2003) Stressful life events and risk of breast cancer in 10,808 women: a cohort study. Am J Epidemiol 157(5):415–423

    Article  PubMed  Google Scholar 

  • Liu P et al (2008) Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst 100(18):1326–1330

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ma J et al (2012) Association of genetic polymorphisms in MDM2, PTEN and P53 with risk of esophageal squamous cell carcinoma. J Hum Genet 57(4):261–264

    Article  CAS  PubMed  Google Scholar 

  • Makhlouf NA et al (2021) Colorectal cancer in Arab world: a systematic review. World J Gastrointest Oncol 13(11):1791–1798. Baishideng Publishing Group Inc.

    Article  PubMed  Google Scholar 

  • Makuku R et al (2021) Current and future perspectives of PD-1/PDL-1 blockade in cancer immunotherapy. J Immunol Res 2021:6661406

    Article  PubMed Central  Google Scholar 

  • Matsuoka T, Yashiro M (2018) Biomarkers of gastric cancer: current topics and future perspective. World J Gastroenterol: WJG 24(26):2818–2832

    Article  PubMed  PubMed Central  Google Scholar 

  • Medeiros R et al (2020) Prevention of human papillomavirus infection. Beyond cervical cancer: a brief review. Acta Medica Portuguesa 33(3):198–201

    Article  PubMed  Google Scholar 

  • Mehrtash H et al (2017) Defining a global research and policy agenda for betel quid and areca nut. Lancet Oncol 18(12):e767–e775

    Article  PubMed  Google Scholar 

  • Mendonça Carneiro M (2021) Cervical cancer elimination: rising up to the challenge. Women Health 61(7):617–618

    Article  PubMed  Google Scholar 

  • Miranda-Filho A, Bray F (2020) Global patterns and trends in cancers of the lip, tongue, and mouth. Oral Oncol 102:104551

    Article  PubMed  Google Scholar 

  • Mummudi N et al (2019) Oral cavity cancer in the Indian subcontinent - challenges and opportunities. Clin Oncol 31(8):520–528

    Article  CAS  Google Scholar 

  • Murillo R et al (2016) Etiology of cervical cancer (C53) in Central and South America. In: Cancer in Central and South America. International Agency for Research on Cancer, Lyon. Available at: http://gco.iarc.fr/includes/CSA_Chp_4-9_Cervix.pdf

    Google Scholar 

  • Napier KJ, Scheerer M, Misra S (2014) Esophageal cancer: a review of epidemiology, pathogenesis, staging workup and treatment modalities. World J Gastrointestinal Oncol 6(5):112–120

    Article  Google Scholar 

  • NCI (2020) Study confirms HPV vaccine prevents cervical cancer, National Cancer Institute. Available at: https://www.cancer.gov/news-events/cancer-currents-blog/2020/hpv-vaccine-prevents-cervical-cancer-sweden-study. Accessed 21 January 2022

  • Pakzad R et al (2016) The incidence and mortality of esophageal cancer and their relationship to development in Asia. Ann Transl Med 4(2):29

    PubMed  PubMed Central  Google Scholar 

  • Pan CQ et al (2016) Tenofovir to prevent hepatitis B transmission in mothers with high viral load. N Engl J Med 374(24):2324–2334

    Article  CAS  PubMed  Google Scholar 

  • Petry KU (2014) HPV and cervical cancer. Scand J Clin Lab Invest. Supplementum 244:59–62; discussion 62

    Article  Google Scholar 

  • Prabhu NT et al (2001) Betel quid chewing among Bangladeshi adolescents living in east London. Int J Pediatric Dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children 11(1):18–24

    Article  CAS  Google Scholar 

  • Pritchard CC et al (2016) Inherited DNA-repair gene mutations in men with metastatic prostate cancer. N Engl J Med 375(5):443–453

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rahman A et al (2014) Evaluation of quality status and detection of adulterants in selected commercial pickles and chutneys based on consumer attitude and laboratory analysis. J Bangladesh Agric Univ 12(1):203–209

    Article  Google Scholar 

  • Rawla P (2019) Epidemiology of prostate cancer. World J Oncol 10(2):63–89

    Article  CAS  PubMed Central  Google Scholar 

  • Recio-Boiles A, Babiker HM (2021) Esophageal cancer. In: StatPearls. StatPearls Publishing, Treasure Island

    Google Scholar 

  • Roshandel G et al (2019) Cancer incidence in Iran in 2014: results of the Iranian National Population-based Cancer Registry. Cancer Epidemiol 61:50–58

    Article  PubMed  Google Scholar 

  • Saidi F et al (2000) Oesophageal cancer among the Turkomans of Northeast Iran. Br J Cancer 83(9):1249–1254

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sandagdorj T et al (2010) Cancer incidence and mortality in Mongolia – National Registry Data. Asian Pacific J Cancer Prevent: APJCP 11(6):1509–1514

    Google Scholar 

  • Schrader KA et al (2016) Germline variants in targeted tumor sequencing using matched Normal DNA. JAMA Oncol 2(1):104–111

    Article  PubMed  PubMed Central  Google Scholar 

  • Semeere AS, Busakhala N, Martin JN (2012) Impact of antiretroviral therapy on the incidence of Kaposi’s sarcoma in resource-rich and resource-limited settings. Curr Opin Oncol 24(5):522–530. Ovid Technologies (Wolters Kluwer Health)

    Article  PubMed  PubMed Central  Google Scholar 

  • Semeere A et al (2016) A prospective ascertainment of cancer incidence in sub-Saharan Africa: the case of Kaposi sarcoma. Cancer Med 5(5):914–928. Wiley

    Article  PubMed  PubMed Central  Google Scholar 

  • Sengayi-Muchengeti M, Joko-Fru WY (2020) Cervical cancer survival in sub-Saharan Africa by age, stage at diagnosis and human development index: a population-based registry study. J Cancer. Wiley Online Library. Available at: https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.33120

  • Shayan SJ et al (2020) Demographic profile of gastric cancer in Afghanistan. Indian J Surg Oncol 11(3):344–347. Springer Science and Business Media LLC

    Article  PubMed  PubMed Central  Google Scholar 

  • Sheh A et al (2011) 17β-estradiol and tamoxifen prevent gastric cancer by modulating leukocyte recruitment and oncogenic pathways in helicobacter pylori-infected INS-GAS male mice. Cancer Prev. AACR. Available at: https://cancerpreventionresearch.aacrjournals.org/content/4/9/1426.short

  • Smigal C et al (2006) Trends in breast cancer by race and ethnicity: update 2006. CA Cancer J Clin 56(3):168–183

    Article  PubMed  Google Scholar 

  • Sobrato I, Busso P, Zanetti R (2010) What are we learning from the new data on cancer incidence in North Africa. Epidemiol Prev 34(1–2):23–26

    PubMed  Google Scholar 

  • Srinivasan S et al (2019) Prostate cancer risk-associated single-nucleotide polymorphism affects prostate-specific antigen glycosylation and its function. Clin Chem 65(1):e1–e9

    Article  PubMed  Google Scholar 

  • Sung H et al (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71(3):209–249

    Article  PubMed  Google Scholar 

  • Tao Z et al (2015) Breast cancer: epidemiology and etiology. Cell Biochem Biophys 72(2):333–338

    Article  CAS  PubMed  Google Scholar 

  • Tappero JW et al (1993) Kaposi’s sarcoma. Epidemiology, pathogenesis, histology, clinical spectrum, staging criteria and therapy. J Am Acad Dermatol 28(3):371–395. Elsevier

    Article  CAS  PubMed  Google Scholar 

  • Thun M et al (2017) Cancer epidemiology and prevention. Oxford University Press

    Book  Google Scholar 

  • Um P (2015) Cancer, definition. In: Highlander SK, Rodriguez-Valera F, White BA (eds) Encyclopedia of metagenomics: environmental metagenomics. Springer US, Boston, pp 65–65

    Google Scholar 

  • Walboomers JM et al (1999) Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 189(1):12–19

    Article  CAS  PubMed  Google Scholar 

  • WHO (2018) Noncommunicable diseases country profiles 2018. World Health Organization. Available at: https://apps.who.int/iris/bitstream/handle/10665/274512/9789241514620-eng.pdf

  • WHO Regional Office for the Western Pacific (2016) Viral hepatitis in Mongolia: situation and response 2015. WHO Regional Office for the Western Pacific

    Google Scholar 

  • Witte JS (2009) Prostate cancer genomics: towards a new understanding. Nat Rev Genet 10(2):77–82

    Article  CAS  PubMed  Google Scholar 

  • Yu H et al (2019) Circulating MicroRNA biomarkers for lung cancer detection in east Asian populations. Cancers 11(3). https://doi.org/10.3390/cancers11030415

  • Yusefi AR et al (2018) Risk factors for gastric cancer: a systematic review. Asian Pacific J Cancer Prevent: APJCP 19(3):591–603

    CAS  Google Scholar 

  • Zabora JR, Macmurray L (2012) The history of psychosocial screening among cancer patients. J Psychosoc Oncol 30(6):625–635

    Article  PubMed  Google Scholar 

  • Zamani N et al (2013) A case-control study of the relationship between gastric cancer and meat consumption in Iran. Arch Iran Med 16(6):324–329

    PubMed  Google Scholar 

  • Zhang Z et al (2014) High-incidence of PTEN mutations in Chinese patients with primary small cell carcinoma of the esophagus. BMC Cancer 14:19

    Article  PubMed  PubMed Central  Google Scholar 

  • Zhou F, Zhou C (2018) Lung cancer in never smokers – the east Asian experience. In: Translational lung cancer research. ncbi.nlm.nih.gov. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6131183/

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Authors and Affiliations

  1. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

    Kawthar Mohamed, Lindelwa Mmema, Laila Rahmah, Fareeda Hashem, Rangarirai Makuku, Amanuel Godana Arero & Nima Rezaei

  2. Universal Scientific Education and Research Network (USERN), Manama, Bahrain

    Kawthar Mohamed & Fareeda Hashem

  3. Department of Biochemistry, University of Port Harcourt, Choba, Nigeria

    Sunny O. Abarikwu

  4. Universal Scientific Education and Research Network (USERN), Choba, Nigeria

    Sunny O. Abarikwu

  5. Universal Scientific Education and Research Network (USERN), Manzini, Eswatini

    Lindelwa Mmema

  6. Department of Community Nutrition School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran

    Aliyu Tijani Jibril

  7. Universal Scientific Education and Research Network (USERN), Sekondi-Takoradi, Ghana

    Aliyu Tijani Jibril

  8. Universal Scientific Education and Research Network (USERN), Jakarta, Indonesia

    Laila Rahmah

  9. Research Center, Department of Microbiology and Immunology, Medical University, Plovdiv, Bulgaria

    Mariya Ivanovska

  10. Universal Scientific Education and Research Network (USERN), Plovdiv, Bulgaria

    Mariya Ivanovska

  11. Department of Physiology, Medical School, Tehran University of Medical Sciences, Tehran, Iran

    Ahmad Mustafa Rahimi

  12. Universal Scientific Education and Research Network (USERN), Kabul, Afghanistan

    Ahmad Mustafa Rahimi & Musa Joya

  13. Radiology Department, Kabul University of Medical Sciences, Kabul, Afghanistan

    Musa Joya

  14. Erasme Hospital, Department of Rheumatology and Physical Medicine, Université Libre de Bruxelles, Brussels, Belgium

    Mickael Essouma

  15. Universal Scientific Education and Research Network (USERN), Yaoundé, Cameroon

    Mickael Essouma

  16. Universal Scientific Education and Research Network (USERN), Harare, Zimbabwe

    Rangarirai Makuku

  17. Department of Cellular and Physiological Sciences, Faculty of Medicine University of British Columbia, Vancouver, BC, Canada

    Niyoosha Yoosefi

  18. Universal Scientific Education and Research Network (USERN), Vancouver, BC, Canada

    Niyoosha Yoosefi

  19. Universal Scientific Education and Research Network (USERN), Addis Ababa, Ethiopia

    Amanuel Godana Arero

  20. Neuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon

    Sara A. Makka

  21. Universal Scientific Education and Research Network (USERN), Beirut, Lebanon

    Sara A. Makka

  22. Head and Neck Surgery Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    Luis Alejandro Boccalatte

  23. Universal Scientific Education and Research Network (USERN), Buenos Aires, Argentina

    Luis Alejandro Boccalatte

  24. Universal Scientific Education and Research Network (USERN), Tehran, Iran

    Nima Rezaei

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Corresponding author

Correspondence to Nima Rezaei .

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Editors and Affiliations

  1. Division of Clinical Immunology, Karolinska University Hospital, Huddinge, Sweden

    Nima Rezaei

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Mohamed, K. et al. (2023). A Global Perspective of Cancer Prevalence: The Causative Agent, the Environment, or the Genes?. In: Rezaei, N. (eds) Handbook of Cancer and Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-80962-1_100-1

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  • DOI: https://doi.org/10.1007/978-3-030-80962-1_100-1

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