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Natural Products and Human Diseases pp 99–121Cite as

Antiviral Plants in View of Avicenna’s The Canon of Medicine and Modern Medicine Against Common Cold

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Part of the book series: Advances in Experimental Medicine and Biology ((PMISB,volume 1328))

Abstract

Common cold is known as a serious clinical problem worldwide. Coronaviruses have long been identified as respiratory pathogens causing “common cold” in healthy people. The pandemic of 2019 novel coronavirus as a serious public health problem and concern has resulted in severe illness and death especially in the elderly. COVID-19 is picking up pace around the world and has spread to more than 219 countries. Due to the very easy spread of COVID-19 and its lack of recognized appropriate treatments and vaccines as well as potential therapeutic effects of several traditional herbal remedies, we decided to gather, evaluate, and compare the potential pharmacological effects of medicinal herbs from Avicenna’s perspective and modern medicine with antiviral properties which may lead to the discovery of suitable traditional treatments to prevent or reduce the adverse symptoms of common cold.

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Abbreviations

ADV:

Adenoviruses

AFP:

α-fetoprotein

ALT:

Alanine aminotransferase

ARV:

Antiretroviral

AST:

Aspartate aminotransferase

AuNPs:

Gold nanoparticles

BeA:

Betulinic acid

cAgNPs:

Citrate-coated silver nanoparticles

CCID50:

Cell culture infectious dose 50%

CI:

Confidence interval

COVID-19:

Coronavirus disease

CoVs:

Coronaviruses

CpHV-1:

Caprine herpesvirus 1

CVB1:

Coxsackievirus B1

DG:

Diammonium glycyrrhizin

EC50:

50% effective concentration

EEE:

Ent-epiafzelechin-(4α→8)-epiafzelechin

EGFP:

Enhanced green fluorescent protein

EO:

Essential oil

EV71:

Enterovirus 71

18β-GA:

18β-glycyrrhetinic acid

GEO:

Ginger essential oil

GL:

glycyrrhizinate

GMK:

Green monkey

GRA:

Glycyrrhizic acid

HA:

Hemagglutination

HBV:

Hepatitis B virus

HCoVs:

Human coronaviruses

HCV:

Hepatitis C virus

HEp-2:

Human epithelial type 2

HGG:

Honey

ginger

and garlic

HIV:

Human immunodeficiency virus

H1N1:

Hemagglutinin type 1 and neuraminidase type 1

HRSV:

Human respiratory syncytial virus

HSV-1:

Herpes simplex virus type 1

IAV:

Influenza A virus

IBV:

Infectious bronchitis virus

IC50:

Half maximal inhibitory concentration

IFIT1:

Interferon-induced protein with tetratricopeptide repeats 1

IFN-β:

Interferon beta

LC3:

light chain 3

LiCl:

lithium chloride

MDBK:

Madin-Darby bovine kidney

MDCK:

Madin-Darby canine kidney

MERS-CoV:

Middle East respiratory syndrome coronavirus

MeV:

Measles virus

NDV:

Newcastle disease virus

NHC:

National Health Commission

NS5B:

Nonstructural 5B

N/V:

nausea and vomiting

PBMCs:

Peripheral blood mononuclear cells

PHS:

P. harmala seeds

PI-3:

Parainfluenza type 3

PRV:

Piscine orthoreovirus

RSV:

Respiratory syncytial virus

SARS:

Severe acute respiratory syndrome

SARS-CoV-2:

Severe acute respiratory syndrome coronavirus 2

TMV:

Tobacco mosaic virus

USA:

the United States of America

WHO:

World Health Organization

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Acknowledgment

The authors wish to thank the Mashhad University of Medical Sciences.

Conflict of Interest

The authors declare that they have no conflict of interests.

Funding

The study was funded by the Research Council of Mashhad University of Medical Sciences, Mashhad, Iran.

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Authors and Affiliations

  1. Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

    Elham Ramazani

  2. Department of Cell and Molecular Biology, Kosar University of Bojnord, Bojnord, Iran

    Elham Ramazani

  3. Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Seyed Ahmad Emami

  4. Department of Prosthodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran

    Nilufar Tayarani-Najaran

  5. Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  6. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  7. School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  8. Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

    Zahra Tayarani-Najaran

Authors
  1. Elham Ramazani
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  2. Seyed Ahmad Emami
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  3. Nilufar Tayarani-Najaran
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  4. Amirhossein Sahebkar
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  5. Zahra Tayarani-Najaran
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Corresponding author

Correspondence to Zahra Tayarani-Najaran .

Editor information

Editors and Affiliations

  1. Pharmacy, Medical Biotechnology, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  2. Diabetes, Endocrinology & Metabolism, The University of Hull, Brough, UK

    Thozhukat Sathyapalan

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Ramazani, E., Emami, S.A., Tayarani-Najaran, N., Sahebkar, A., Tayarani-Najaran, Z. (2021). Antiviral Plants in View of Avicenna’s The Canon of Medicine and Modern Medicine Against Common Cold. In: Sahebkar, A., Sathyapalan, T. (eds) Natural Products and Human Diseases. Advances in Experimental Medicine and Biology(), vol 1328. Springer, Cham. https://doi.org/10.1007/978-3-030-73234-9_7

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