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Environmental Factors Responsible for Obesity and Insulin Resistance in Polycystic Ovary Syndrome

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Impact of Polycystic Ovary, Metabolic Syndrome and Obesity on Women Health

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Abstract

It has been shown that environmental factors play a role in the development of obesity and insulin resistance in PCOS women. There is a bulk of evidence that endocrine-disrupting chemicals, advanced glycated end products, and vitamin D deficiency contribute to these disorders. The results of in vitro and in vivo studies have demonstrated different mechanisms involved in the development of these conditions. They suggest new ways of treatment. In addition, they point to the importance of avoidance of exposure to deleterious environmental factors.

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Author information

Authors and Affiliations

  1. Department of Endocrinology, Diabetes and Isotope Therapy, Wroclaw Medical University, Wrocław, Poland

    Andrzej Milewicz & Anna Brona

  2. Department of Endocrinology, Lviv National Medical University, Lviv, Ukraine

    Alina Urbanovych

Authors
  1. Andrzej Milewicz
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  2. Alina Urbanovych
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  3. Anna Brona
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Correspondence to Andrzej Milewicz .

Editor information

Editors and Affiliations

  1. International Society of Gynecological Endocrinology, Pisa, Italy

    Andrea R. Genazzani

  2. Endocrinology Department, Hospital Sant Joan de Déu Barcelona, Barcelona, Spain

    Lourdes Ibáñez

  3. Department of Endocrinology, Diabetology, Wrocław Medical University, Wroclaw, Poland

    Andrzej Milewicz

  4. Obstetrics and Gynecology, Gynaecworld, Mumbai, India

    Duru Shah

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Milewicz, A., Urbanovych, A., Brona, A. (2021). Environmental Factors Responsible for Obesity and Insulin Resistance in Polycystic Ovary Syndrome. In: Genazzani, A.R., Ibáñez, L., Milewicz, A., Shah, D. (eds) Impact of Polycystic Ovary, Metabolic Syndrome and Obesity on Women Health. ISGE Series. Springer, Cham. https://doi.org/10.1007/978-3-030-63650-0_4

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  • DOI: https://doi.org/10.1007/978-3-030-63650-0_4

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