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Gynaecological Considerations in PoTS

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Postural Tachycardia Syndrome

Abstract

The gynaecological impact of PoTS is associated with hypermobile Ehlers Danlos syndrome (hEDS), mast cell activation syndrome (MCAS), histamine intolerance and the influence of female sex hormones. The menstrual cycle plays a key role in changing the cardiovascular environment as well producing inflammatory episodes during menstruation. Women with PoTS have more menstrual irregularities and also suffer from pelvic pain, and vulval inflammatory and pain conditions. Treatment can involve suppressing the menstrual cycle hormonally or using type 1 and 2 histamine receptor blockers or mast cell stabilising medications. There is a higher prevalence of vaginal prolapse which is more challenging to treat due to the association with hypermobile EDS.

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Authors and Affiliations

  1. Urogynaecology Department, St Mary’s Hospital, Imperial College London, London, UK

    Visha Tailor & Vik Khullar

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  1. Visha Tailor
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  2. Vik Khullar
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Correspondence to Vik Khullar .

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Editors and Affiliations

  1. King's College Hospital, London, UK

    Nicholas Gall

  2. Faculty of Health, Education and Life Sciences, Birmingham City University, Birmingham, UK

    Lesley Kavi

  3. Barts NIHR Biomedical Research Centre, William Harvey Research Institute, Queen Mary University of London, London, UK

    Melvin D. Lobo

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Tailor, V., Khullar, V. (2021). Gynaecological Considerations in PoTS. In: Gall, N., Kavi, L., Lobo, M.D. (eds) Postural Tachycardia Syndrome. Springer, Cham. https://doi.org/10.1007/978-3-030-54165-1_18

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  • DOI: https://doi.org/10.1007/978-3-030-54165-1_18

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-54164-4

  • Online ISBN: 978-3-030-54165-1

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