Abstract
Histology, the branch of anatomy also known as microscopic anatomy, is the study of the structure and function of the body’s tissues. To gain an understanding of the tissues of the body is to learn the foundational underpinnings of anatomy and achieve a deeper, more intimate insight into how the body is constructed, functions, and undergoes pathological change. Histology, therefore, is an integral element of basic science education within today’s medical curricula. Its development as a discipline is inextricably linked to the evolution of the technology that allows us to visualize it. This chapter takes us on the journey through the past, present, and future of histology and its education; from technologies grounded in ancient understanding and control of the properties of light, to the ingenuity of crafting glass lenses that led to the construction of the first microscopes; traversing the second revolution in histology through the development of modern histological techniques and methods of digital and virtual microscopy, which allows learners to visualize histology anywhere, at any time; to the future of histology that allows flexible self-directed learning through social media, live-streaming, and virtual reality as a result of the powerful smart technologies we all carry around in our pockets. But, is our continuous pursuit of technological advancement projecting us towards a dystopian world where machines with artificial intelligence learn how to read histological slides and diagnose the diseases in the very humans that built them?
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Notes
- 1.
For fun, see also Bacon’s work in creating brazen (brass) head automatons that were able to predict the future. An invention that led to some thinking he was perhaps not a friar but rather a practitioner of the dark arts.
References
Abel E, Pantanowitz L, Aeffner F et al (2019) Computational pathology definitions, best practices, and recommendations for regulatory guidance: a white paper from The Digital Pathology Association. J Pathol 249:286–294
Ahmed R, Shamim KM, Talukdar HK, Parvin S (2018) Light microscopy for teaching-learning in histology practical in undergraduate medical education of Bangladesh: a teacher’s perspective. Southeast Asian J Med Educ 12:26–31
Alammary A, Sheard J, Carbone A (2014) Blended learning in higher education: three different design approaches. Australas J Educ Technol 30:440–454
Arroyo-Jimenez MDM, Marcos P, Martinez-Marcos A et al (2005) Gross anatomy dissections and self-directed learning in medicine. Clin Anat 18:385–391
Baeyer A (1875) Zur geschichte des eosins. Ber Dtsch Chem Ges 8:146–148
Balemans MCM, Kooloos JGM, Donders ART, Van der Zee CEEM (2016) Actual drawing of histological images improves knowledge retention. Anat Sci Educ 9:60–70
Balogun WG (2019) Using electronic tools and resources to meet the challenges of anatomy education in sub-Saharan Africa. Anat Sci Educ 12:97–104
Barbeau ML, Johnson M, Gibson C, Rogers KA (2013) The development and assessment of an online microscopic anatomy laboratory course. Anat Sci Educ 6:246–256
Barry DS, Marzouk F, Chulak-Oglu K et al (2016) Anatomy education for the YouTube generation. Anat Sci Educ 9:90–96
Bell CS (1966) The early history of the microscope. Bios 37(2):51–60
Bergman EM, Prince KJAH, Drukker J, van der Vleuten CPM, Scherpbier AJJA (2008) How much anatomy is enough?. Anatomical Sciences Education 1(4):184–188
Bergman EM, Vleuten CPMD, Scherpbier AJJA (2011) Why don’t they know enough about anatomy? A narrative review. Med Teach 33:403–409
Bergman E, Verheijen I, Scherpbier A et al (2014) Influences on anatomical knowledge: the complete arguments. Clin Anat 27:296–303
Berners-Lee T (1989) Information management: a proposal. http://info.cern.ch/Proposal.html. Accessed 11 Feb 2020
Berry GP, Clark SL, Dempsey EW et al (1956) Association of American Medical Colleges: the teaching of anatomy and anthropology in medical education. In: Report of the Third Teaching Institute, Association of American Medical Colleges, Swampscott, MA. 18–22 October 1955. J Med Educ 31:1–146
Bigelow J (1859) The death of Pliny the elder. Mem Am Acad Arts Sci 6(2):223–227
Blake JB (1980) Anatomy. In: Numbers RL (ed) The education of American physicians: historical essays. University of California Press, California
Blake CA, Lavoie HA, Millette CF (2003) Teaching medical histology at the University of South Carolina School of Medicine: transition to virtual slides and virtual microscopes. Anat Rec 275B:196–206
Bloodgood RA, Ogilvie RW (2006) Trends in histology laboratory teaching in United States medical schools. Anat Rec B New Anat 289:169–175
Blum F (1893a) Der formaldehyd als antisepticum. Munch Med Wochenschr 40(32):601–602
Blum F (1893b) Der formaldehyd als härtungsmittel. Z Wiss Mikrosk 10:314–315
Böhmer F (1865) Zur pathologischen anatomie der meningitis cerebromedullaris epidemica. Aerztl Intelligenzb Munchen 12:539–550
Bonaini F (1845) Chronica antiqua conventus sanctae Catharine de Pisis. Arch Stor Ital 6(2):391–593
Border S, Hennessy C, Pickering J (2019) The rapidly changing landscape of student social media use in anatomy education. Anat Sci Educ 12:577–579
Borowsky AD, Glassy EF, Wallace WD et al. (2020) Digital whole slide imaging compared with light microscopy for primary diagnosis in surgical pathology. Arch Pathol Lab Med. Advanced online publication. https://doi.org/10.5858/arpa.2019-0569-OA
Bostock J (1855a) The natural history. Pliny the Elder (trans Bostock J, Riley HT). Book XXXVI, Chapter 67. Taylor and Francis
Bostock J (1855b) The natural history. Pliny the Elder, (trans Bostock J, Riley HT). Book XXXVII, Chapter 10. Taylor and Francis
Boyce BF (2017) An update on the validation of whole slide imaging systems following FDA approval of a system for a routine pathology diagnostic service in the United States. Biotech Histochem 92:381–389
Braun MW, Kearns KD (2008) Improved learning efficiency and increased student collaboration through use of virtual microscopy in the teaching of human pathology. Anat Sci Educ 1:240–246
Brown PJ, Fews D, Bell NJ (2016) Teaching veterinary histopathology: a comparison of microscopy and digital slides. J Vet Med Educ 43:13–20
Burgess DS (2004) Laser microdissection: making inroads in research. Biophoton Int 11:46–49
Burke RB (1962) The opus majus of Roger Bacon, vol 2. Russel and Russel Inc, p 574
Campanella G, Hanna MG, Geneslaw L et al (2019) Clinical-grade computational pathology using weakly supervised deep learning on whole slide images. Nat Med 25:1301–1309
Carpenter WB, Dallinger WH (1901) The microscope and its revelations, 8th edn. P Blakiston’s Son and Co, Philadelphia, p 125
Chen F, Lui AM, Martinelli SM (2017) A systematic review of the effectiveness of flipped classrooms in medical education. Med Educ 51:585–597
Chvátal A (2017) Jan Evangelista Purkyně (1787–1869) and his instruments for microscopic research in the field of neuroscience. J Hist Neurosci 26(3):238–256
CISCO (2019) Cisco Visual Networking Index: forecast and trends, 2017–2022. White Paper. Available: https://www.cisco.com/c/en/us/solutions/collateral/service-provider/visual-networking-index-vni/white-paper-c11-741490.html
Clarke J (1910) Physical science in the time of Nero: being a translation of the Quaestiones Naturales of Seneca (trans Clarke J). Book I, Chapter VI. Macmillan and Co. Ltd, p 29
Codd AM, Choudhury B (2011) Virtual reality anatomy: is it comparable with traditional methods in the teaching of human forearm musculoskeletal anatomy? Anat Sci Educ 4:119–125
Cole D, Rengasamy E, Batchelor S et al (2017) Using social media to support small group learning. BMC Med Educ 17:201
Coleman R (2009) Can histology and pathology be taught without microscopes? The advantages and disadvantages of virtual histology. Acta Histochem 111:1–4
Collier B (1970) The little engines that could’ve: the calculating machines of Charles Babbage. Thesis, Harvard University
Cooke M, Irby D, O’Brien B (2010) Educating physicians: a call for reform of medical school and residency. Jossey-Bass, San Francisco
Cotter JR (2001) Laboratory instruction in histology at the University of Buffalo: recent replacement of microscope exercises with computer applications. Anat Rec 265:212–221
Craig S, Tait N, Boers D, McAndrew D (2010) Review of anatomy education in Australian and New Zealand medical schools. ANZ J Surg 80:212–216
Daly CJ (2018) The future of education? Using 3D animation and virtual reality in physiology teaching. Physiol News 111:43
Davis FD, Bagozzi RP, Warshaw PR (1989) User acceptance of computer technology: a comparison of two theoretical models. Manag Sci 35:903–1028
Day LJ (2018) A gross anatomy flipped classroom effects performance, retention, and higher-level thinking in lower performing students. Anat Sci Educ 11:565–574
Dee FR (2009) Virtual microscopy in pathology education. Hum Pathol 40:1112–1121
Dee FR, Lehman JM, Consoer D et al (2003) Implementation of virtual microscope slides in the annual pathobiology of cancer workshop laboratory. Hum Pathol 34(5):430–436
del Migliore FL (1684) Firenze città nobilissima illustrata [The noble city of Florence illustrated]. Nella Stamp della Stella, p 431
Donnelly AD, Mukherjee MS, Lyden ER et al (2013) Optimal z-axis scanning parameters for gynecologic cytology specimens. J Pathol Inform 4:38
Drake RL, Lowrie DJ Jr, Prewitt CM (2002) Survey of gross anatomy, microscopic anatomy, neuroscience, and embryology courses in medical school curricula in the United States. Anat Rec 269:118–122
Drake RL, McBride JM, Lachman N, Pawlina W (2009) Medical education in the anatomical sciences: the winds of change continue to blow. Anat Sci Educ 2:253–259
Drake RL, McBride JM, Pawlina W (2014) An update on the status of anatomical sciences education in United States medical schools. Anat Sci Educ 7:321–325
Duffy TP (2011) The Flexner report—100 years later. Yale J Biol Med 84(3):269–276
El Bialy S, Jalali A (2015) Go where the students are: a comparison of the use of social networking sites between medical students and medical educators. JMIR Med Educ 1:e7
Falah J, Khan S, Alfalah T et al (2014) Virtual reality medical training system for anatomy education. Sci Inform Conf 37:752–758
Farah CS, Maybury S (2009) The e-evolution of microscopy in dental education. J Dent Educ 73:942–949
Farey JE, Sandeford JC, Evans-McKendry GD (2014) Medical students call for national standards in anatomical education. ANZ J Surg 84:813–815
Felszeghy S, Pasonen-Seppänen S, Koskela A, Mahonen A (2017) Student-focused virtual histology education: do new scenarios and digital technology matter? Med Ed Publish. https://doi.org/10.15694/mep.2017.000154
Fernandes CIR, Bonan RF, Bonan PRF et al (2018) Dental student’s perceptions and performance in use of conventional and virtual microscopy in oral pathology. J Dent Educ 82:883–890
Findlater GS, Kristmundsdottir F, Parson SH, Gillingwater TH (2012) Development of a supported self-directed learning approach for anatomy education. Anat Sci Educ 5:114–121
Fitzgerald JEF, White MJ, Tang SW et al (2008) Are we teaching sufficient anatomy at medical school? The opinions of newly qualified doctors. Clin Anat 21:718–724
Fleagle TR, Borcherding NC, Harris J, Hoffmann DS (2018) Application of flipped classroom pedagogy to the human gross anatomy laboratory: student preferences and learning outcomes. Anat Sci Educ 11:285–296
Flexner A (1910) Medical education in the United States and Canada: a report to the Carnegie Foundation for the Advancement of Teaching. Carnegie Foundation for the Advancement of Teaching, New York
Flowers TH (1983) The design of colossus. IEEE Ann Hist Comput 5(3):239–252
Fu X, Klepeis V, Yagi Y (2018) Evaluation of an automated tissue sectioning machine for digital pathology. Diagn Pathol 4:267
Gartner LP (2003) Anatomical sciences in the allopathic medical school curriculum in the United States between 1967-2001. Clin Anat 16:434–439
Gatumu MK, MacMillan FM, Langton PD et al (2014) Evaluation of usage of virtual microscopy for the study of histology in the medical, dental, and veterinary undergraduate programs of a UK University. Anat Sci Educ 7:389–398
Gillingwater TH (2008) The importance of exposure to human material in anatomical education: a philosophical perspective. Anat Sci Educ 1:264–266
Goes FJ (2013) The eye in history. Jaypee Brothers Medical Publisher, New Delhi, p p130
Goldberg HR, Dintzis R (2007) The positive impact of team-based virtual microscopy on student learning in physiology and histology. Adv Physiol Educ 31:261–265
Guckian J, Leighton J, Frearson R et al (2019) The next generation: how medical students use new social media to support their learning. Med Ed Publish. https://doi.org/10.15694/mep.2019.000227.1
Gupta Y, Morgan M, Singh A, Ellis H (2008) Junior doctors’ knowledge of applied clinical anatomy. Clin Anat 21:334–338
Hanna MG, Ahmed I, Nine J et al (2018) Augmented reality technology using Microsoft HoloLens in anatomic pathology. Arch Pathol Med 142:638–644
Harris T, Leaven T, Heidger P, Kreiter C, Duncan J, Dick F (2001) Comparison of a virtual microscope laboratory to a regular microscope laboratory for teaching histology. Anat Rec 265:10–14
Harvey W (1628) On the motion of the heart and blood in animals (trans: Willis R). PF Collier & Son, New York, p p1910
Heidger PM Jr, Dee F, Consoer D et al (2002) Integrated approach to teaching and testing in histology with real and virtual imaging. Anat Rec 269:107–112
Henle J (1838) Ueber die ausbreitung des epithelium im menschlichen körper. In Müller’s Archiv 5:103–128
Henle J (1841) Allgemeine anatomie. Lehre von den mischungs und formbestandtheilen des menschlichen körpers. In Vom bau des menschlichen körpers (von Sommerring ST), vol 6. Leipzig: Voss
Hennessy CM (2017) Lifting the negative cloud of social media use within medical education. Anat Sci Educ 10:98–99
Hennessy CM, Royer DF, Meyer AJ, Smith CF (2020) Social media guidelines for anatomists. Anat Sci Educ.: Advanced online publication. https://doi.org/10.1002/ASE.1948
Heylings DJA (2002) Anatomy 1999–2000: the curriculum, who teaches it and how? Med Educ 36:702–710
Hofmann AW (1867) Contributions to the history of methylic aldehyde. Proc R Soc Lond 16:156–159
Hooke R (1665) Micrographia: or some physiological descriptions of minute bodies made by magnifying glasses. Jo Martyn and Ja Allestry, Printers to the Royal Society, London, pp 112–120
Hootsuite (2020) 37 Instagram Stats That Matter to Marketers in 2020. [ONLINE] Available at: https://blog.hootsuite.com/instagram-statistics/. (Accessed 21 Feb 2020
Hortsch M (2013) From microscopes to virtual reality: how our teaching of histology is changing. J Cytol Histol 4:e108
Husmann PR, O’Loughlin VD, Braun MW (2009) Quantitative and qualitative changes in teaching histology by means of virtual microscopy in an introductory course in human anatomy. Anat Sci Educ 2:218–226
Inui T (2003) A flag in the wind: educating for professionalism in medicine. Association of American Medical Colleges, Washington, DC
Jones DG (2016) YouTube anatomy education: sources of ethical perplexity. Anat Sci Educ 9:500–501
Kahr B, Lovell S, Subramony JA (1998) The progress of logwood extract. Chirality 10:66–77
Kalderon AE (1983) The evolution of microscope design from its invention to the present days. Am J Surg Pathol 7:95–102
Keenan ID, Slater JD, Matthan J (2018) Social media: insights for medical education from instructor perceptions and usage. Med Ed Publish. https://doi.org/10.15694/mep.2018.0000027.1
Khalil MK, Kirkley DL, Kibble JD (2013) Development and evaluation of an interactive electronic laboratory manual for cooperative learning of medical histology. Anat Sci Educ 6:342–350
Kisch B (1954) Forgotten leaders in modern medicine, Valentin, Gruby, Remak, Auerbach. Trans Am Philos Soc 44:139–317
Knight TA (1803) Account of some experiments on the descent of the sap in trees. Philos Trans R Soc Lond 93:277–289
Koelzer VH, Sirinukunwattana K, Rittscher J et al (2019) Precision immunoprofiling by image analysis and artificial intelligence. Virchows Arch 474:511–522
Kolitsky MA (2014) 3D printed tactile learning objects: proof of concept. J Blin Innov Res 4(1)
Kolliker A (1899) Erinnerungen aus meinem Leben. W Engelmann, Leipzig, p 8
Koury HF, Leonard CJ, Carry PM, Lee LMJ (2019) An expert derived feedforward histology module improves pattern recognition efficiency in novice students. Anat Sci Educ 12:645–654
Krippendorf BB, Lough J (2005) Complete and rapid switch from light microscopy to virtual microscopy for teaching medical histology. Anat Rec B New Anat 285:19–25
Lee LMJ, Gould DJ (2014) Educational implications of a social networking application, Twitter™, for anatomical sciences. Med Sci Educ 24:273–278
Lee LMJ, Goldman HM, Hortsch M (2018) The virtual microscopy database-sharing digital microscope images for research and education. Anat Sci Educ 11:510–515
Leeuwenhoeck A (1677) Observation, communicated to the publisher by Mr. Antony van Leeuwenhoeck, in a Dutch letter of the 9 October 1676 here English’d: concerning little animals by him observed in rain-well-sea and snow water; as also in water wherein pepper had lain infused. Philos Trans 12:821–831
Leicester HM (1940) Alexander Mikhailovich Butlerov. J Chem Educ 17(5):203
Letocha CE (1986) The origin of spectacles. Surv Ophthalmol 31(3):185–188
Leung K-K, Lu K-S, Huang T-S, Hsieh B-S (2006) Anatomy instruction in medical schools: connecting the past and the future. Adv Health Sci Educ 11:209–215
Levinson AJ, Weaver B, Garside S et al (2007) Virtual reality and brain anatomy: a randomised trial of e-learning instructional designs. Med Educ 41:495–501
Lewis TL (2017) Social media and student engagement in anatomy education. Anat Sci Educ 10:508
Lewis TL, Sagmeister ML, Miller GW et al (2016) Anatomy, radiology, and practical procedure education for foundational doctors in England: a national observational study. Clin Anat 29:982–990
Ling Y, Swanson DB, Holtzman K, Bucak SD (2008) Retention of basic science information by senior medical students. Acad Med 83:S82–S85
Litchfield D, Ball LJ, Donovan T et al (2010) Viewing another person’s eye movements improves identification of pulmonary nodules in chest x-ray inspection. J Exp Psychol Appl 16:251–262
Lowe AJ (2018) E-learning in medical education: one size does not fit all. Anat Sci Educ 11:100–101
Ma M, Fallavollita P, Seelbach I et al (2016) Personalized augmented reality for anatomy education. Clin Anat 29:446–453
Marsland MJ, Lazarus MD (2018) Ask an anatomist: Identifying global trends, topics and themes of academic anatomists using twitter. Anatomical Sciences Education 11(3):270–281
Mauchly HP (1997) Before the ENIAC. IEEE Ann Hist Comput 19(2):25–30
Mayer RE (2009) Multimedia learning (2nd ed.). Cambridge University Press
Mayer RE (2010) Applying the science of learning to medical education. Med Educ 44:543–549
Mayer RE (2014) Cognitive theory of multimedia learning. In: Mayer RE (ed) The Cambridge handbook of multimedia learning, 2nd edn. Cambridge University Press, New York
Mayer RE, Moreno R (2003) Nine ways to reduce cognitive load in multimedia learning. Educ Psychol 38:43–52
McBride JM, Drake RL (2018) National survey on anatomical sciences in medical education. Anat Sci Educ 11:7–14
McLean S, Attardi SM, Faden L, Goldszmidt M (2016) Flipped classrooms and student learning: not just surface gains. Adv Physiol Educ 40:47–55
McReady ZR, Jham BC (2013) Dental students’ perceptions of the use of digital microscopy as part of an oral pathology curriculum. J Dent Educ 77:1624–1628
Means B, Toyama Y, Murphy R, Baki M (2013) The effectiveness of online and blended learning: a meta-analysis of the empirical literature. Teach Coll Rec 115:1–47
Medical Futurist (2018) The digital future of pathology – the medical futurist. [online] Available at: https://medicalfuturist.com/digital-future-pathology/. Accessed 12 Sept 2019
Merkel F (1891) Jacob Henle: a German scholarly life; according to records and memories. Brunswick:154–155
Metter DM, Colgan TJ, Leung ST et al (2019) Trends in the US and Canadian pathologist workforces from 2007 to 2017. JAMA Netw Open 2:e194337
Miller GW, Lewis TL (2016) Anatomy education for the YouTube generation: technical, ethical, and educational considerations. Anat Sci Educ 9:496–497
Mione S, Valcke M, Cornelissen M (2013) Evaluation of virtual microscopy in medical histology teaching. Anat Sci Educ 6:307–315
Mione S, Valcke M, Cornelissen M (2016) Remote histology learning from static versus dynamic microscopic images. Anat Sci Educ 9:222–230
Mollenhoff CR (1988) Atanasoff: forgotten father of the computer. Iowa State University Press, Ames
Morton DA, Colbert-Getz JM (2017) Measuring the impact of the flipped anatomy classroom: the importance of categorizing an assessment by Bloom’s taxonomy. Anat Sci Educ 10:170–175
Moxham BJ, Emmanouil-Nikoloussi E, Brenner E et al (2017) The attitudes of medical students in Europe toward the clinical importance of histology. Clin Anat 30:635–643
Müller J (1838) On the nature and structural characteristics of cancer and of those morbid growths which may be confounded with it (trans: West C). In Med Chir Rev (1840) 33(65):119–148
Nauhria S, Ramdass PVAK (2019) Randomized cross-over study and a qualitative analysis comparing virtual microscopy and light microscopy for learning undergraduate histopathology. Indian J Pathol Microbiol 62:84–90
Nicholson DT, Chalk C, Funnell WRJ, Daniel SJ (2006) Can virtual reality improve anatomy education? A randomized controlled study of a computer-generated three-dimensional anatomical ear model. Med Educ 40:1081–1087
Niemiec CP, Ryan RM (2009) Autonomy, competence, and relatedness in the classroom: applying self-determination theory to educational practice. Theory Res Educ 7:133–144
Oberlo (2019) 10 Twitter statistics every marketer should know in 2020 [Infographic]. [ONLINE] Available at: https://au.oberlo.com/blog/twitter-statistics. Accessed 21 Feb 2020
Onozato ML, Hammond S, Merren M, Yagi Y (2013) Evaluation of a completely automated tissue-sectioning machine for paraffin blocks. J Clin Pathol 66:151–154
Ortiz-Hidalgo C, Pina-Oviedo S (2019) Hematoxylin: Mesoamerica’s gift to histopathology. Palo de Campeche (logwood tree), pirates’ most desired treasure, and irreplaceable tissue stain. Int J Surg Pathol 27(1):4–14
Pakurar AS, Bigbee JW (2004) Digital histology: an interactive CD atlas with review text. Wiley, Hoboken
Parker LM (2002) Anatomical dissection: why are we cutting it out? Dissection in undergraduate teaching. ANZ J Surg 72:910–912
Parker EU, Reder NP, Glasser D et al (2017) NDER: a novel web application for teaching histology to medical students. Acad Pathol 4:1–5
Parwani AV (2019) Next generation diagnostic pathology: use of digital pathology and artificial intelligence tools to augment a pathological diagnosis. Diagn Pathol 14:138
Paulsen FP, Eichhorn M, Brauer L (2010) Virtual microscopy-the future of teaching histology in the medical curriculum? Ann Anat 192:378–382
Payne K, Keith MJ, Schuetzler RM et al (2017) Examining the learning effects of live streaming video game instruction over Twitch. Comput Hum Behav 77:95–109
Peplow PV (1990) Self-directed learning in anatomy: incorporation of case-based studies into a conventional medical curriculum. Med Educ 24:426–432
Perez S (2019) Twitch continues to dominate live streaming with its second-biggest quarter to date. [online] Techcrunch.com. Available at: https://techcrunch.com/2019/07/12/twitch-continues-to-dominate-live-streaming-with-its-second-biggest-quarter-to-date/. Accessed 16 Feb. 2020
Pickering JD (2014) Taking human anatomy drawings for teaching outside the classroom. Surg Radiol Anat 36:953–954
Pickering JD (2015) Anatomy drawing screencasts: enabling flexible learning for medical students. Anat Sci Educ 8:249–257
Pickering JD, Joynes VCT (2016) A holistic model for evaluating the impact of individual technology-enhanced learning resources. Med Teach 38:1242–1247
Pickering JD, Lazarus MD, Hallam JL (2019) A practitioner’s guide to performing a holistic evaluation of technology-enhanced learning in medical education. Med Sci Educ 29:1095–1102
Pinder KE, Ford JC, Ovalle WK (2008) A new paradigm for teaching histology laboratories in Canada’s first distributed medical school. Anat Sci Educ 1:95–101
Pratt RL (2009) Are we throwing histology out with the microscope? A look at histology from the physician’s perspective. Anat Sci Educ 2:205–209
Prince KHAH, Scherpbier AJAA, van Mameren H et al (2005) Do students have sufficient knowledge of clinical anatomy? Med Educ 39:326–332
Purkyně JE (1834) Der microtomische quetscher, ein bei mikroscopischen untersuchungen unentbehrliches instrument (The microtomic compressor, an instrument indispensable in microscopical investigations). Müller’s Archiv 1:385–390
Purtle HR (1973) History of the microscope. In: Gray P (ed) The encyclopedia of microscopy and microtechnique. Van Nostrand Reinhold, New York, pp 252–260
Raikos A, Waidyasekara P (2014) How useful is YouTube in learning heart anatomy? Anat Sci Educ 7:12–18
Reeve J (2002) Self-determination theory applied to educational settings. In: Deci EL, Ryan RM (eds) Handbook of self-determination research. University of Rochester Press, Rochester
Robboy SJ, Weintraub S, Horvath AE et al (2013) Workforce Project Work Group. Pathologist workforce in the United States: I. development of a predictive model to examine factors influencing supply. Arch Pathol Lab Med 137(12):1723–1732
Rojo MG, García GB, Mateos CP et al (2006) Critical comparison of 31 available digital slide systems in pathology. Int J Surg Pathol 14(4):285–305
Ronchi V (1946) Perche non si ritrova l’'inventore degli occhiale? (Why hasn't the inventor of eyeglasses been found?). Rivista di Oftalmologia 1:140–144
Rosen E (1956a) The invention of eyeglasses, part 1. J Hist Med All Sci 11(1):13–46
Rosen E (1956b) The invention of eyeglasses, part 2. J Hist Med All Sci 11(1):183–218
Ross B, Gage K (2006) Global perspectives on blended learning: insight from WebCT and our customers in higher education. In: Bonk CJ, Graham CR (eds) Handbook of blended learning: global perspectives, local designs. Pfeiffer Publishing, San Francisco
Ryan RM, Deci EL (2000) Self-determination theory and the facilitation of intrinsic motivation, social development and well-being. Am Psychol 55:68–78
Satta G, Edmonstone J (2018) Consolidation of pathology services in England: have savings been achieved? BMC Health Serv Res 18:862
Schmidt H (1998) Integrating the teaching of basic sciences, clinical sciences, and biopsychosocial issues. Acad Med 73:S24–S31
Schutte A, Braun M (2009) Virtual microscopy: experiences of a large undergraduate anatomy course. HAPS Educ 14:39–42
Scoville SA, Buskirk TD (2007) Traditional and virtual microscopy compared experimentally in a classroom setting. Clin Anat 20:565–570
Seymour RB, Kauffman GB (1992) Formaldehyde: a simple compound with many uses. J Chem Educ 69(6):457
Sieben A, Oparka R, Erolin C (2017) Histology in 3D: development of an online interactive student resource on epithelium. J Vis Commun Med 40:58–65
Silage DA, Gil J (1985) Digital image tiles: a method for the processing of large sections. J Microsc 138(2):221–227
Singer C (1915) The dawn of microscopical discovery. J Roy Micr Soc Aug:336–338
Sjoblom M, Hamari J (2017) Why do people watch others play video games? An empirical study on the motivations of Twitch users. Comput Hum Behav 75:985–996
Sleeman J, Lang C, Dakich E (2020) Social media, learning and connections for international students: the disconnect between what students use and the tools learning management systems offer. Australas J Educ Tec 36:44–56
Smith M (1996) Ptolemy’s theory of visual perception: an English translation of the optics with introduction and commentary. Trans Am Philos Soc 86(2):231
Smith M (2010) Alhacen’s theory of visual perception: a critical edition with English translation and commentary of book 7 of Alhacen’s ‘De Aspectibus’, the medieval Latin version of Ibn al-Haytham’s ‘Kitāb al-Manāẓir’. Trans Am Philos Soc New Series 100(3):309
Smythe G, Hughes D (2008) Self-directed learning in gross human anatomy: assessment outcomes and student perceptions. Anat Sci Educ 1:145–153
Stern N (1979) The BINAC: a case study in the history of technology. IEEE Ann Hist Comput 1(1):9–20
Stone DM, Barry DS (2019) Improving virtual learning interactions: reducing transactional distance of online anatomy modules. Anat Sci Educ 12:686–687
Sugand K, Abrahams P, Khurana A (2010) The anatomy of anatomy: a review for its modernization. Anat Sci Educ 3:83–93
Szymas J, Lundin M (2011) Five years of experience teaching pathology to dental students using the WebMicroscope. Diagn Pathol 6:S13
Thompson AR, Lowrie DJ Jr (2017) An evaluation of outcomes following the replacement of traditional histology laboratories with self-study modules. Anat Sci Educ 10:276–285
Tuchman AM (1993) Science, medicine, and the state in Germany: the case of Baden, 1815–1871. Oxford University Press, New York
Turing AM (1937) On computable numbers with an application to the Entscheidungsproblem. P Lond Math Soc 42(2):230–265
Turney BW (2007) Anatomy in a modern medical curriculum. Ann R Coll Surg Engl 89:104–107
van Zuylen J (1981) The microscopes of Antoni van Leeuwenhoek. J Microsc 121:309–328
von Waldeyer W (1863) Untersuchungen über den ursprung und den verlauf des axsencylinders bei wirbellosen und wirbeltieren sowie über dessen endverhalten in der quergestreiften muskelfaser [Studies on the origin and course of the axon cylinder in invertebrates and vertebrates as well as on its behavior in the cross-striated muscle fiber]. Z Rat Med 20:193–256
Waterston SW, Stewart IJ (2005) Survey of clinicians’ attitudes to anatomical teaching and knowledge of medical students. Clin Anat 18:380–384
Weaker FJ, Herbert DC (2009) Transition of a dental histology course from light to virtual microscopy. J Dent Educ 73:1213–1221
Weinstein RS (1986) Prospects for telepathology. Hum Pathol 17(5):433–434
Weinstein RS, Descour MR, Liang C et al (2004) An array microscope for ultrarapid virtual slide processing and telepathology: design, fabrication, and validation study. Hum Pathol 35:1303–1314
West Jr D (2017) Digital pathology gives rise to computational pathology. [ONLINE] Available at: http://www.clpmag.com/2017/10/digital-pathology-gives-rise-computational-pathology/. Accessed 1 Feb 2020
Whelan E, Isla N, Brooks S (2019) The effect of social media overload on academic performance. Available at SSRN: https://ssrn.com/abstract=3498265
Wilson AB, Taylor MA, Klein BA et al (2016) Meta-analysis and review of learner performance and preference: virtual versus optical microscopy. Med Educ 50:428–440
Wissozky N (1877) Ueber das eosin als reagens auf hämoglobin und die bildung von blutgefässen und blutkörperchen bei Säugetier und Hühnerembryonen [Eosin as a reagent to hemoglobin and the formation of blood vessels and blood cells in mammalian and chick embryos]. Archiv Mikr Anat 13:479–496
Xu C-J (2013) Is virtual microscopy really better for histology teaching? Anat Sci Educ 6:138
Yen PY, Hollar MR, Griffy H, Lee LMJ (2014) Students’ expectations of an online histology course: a qualitative study. Med Sci Educ 24:75–82
Young J (1929) Malpighi’s “De pulmonibus”. Proc R Soc Med 23(1):1–11
YouTube (2020) YouTube for Press. [ONLINE] Available at: https://www.youtube.com/intl/en-GB/about/press/. Accessed 21 Feb 2020
Zito FA, Marzullo F, D’Errico D et al (2004) Quicktime virtual reality technology in light microscopy to support medical education in pathology. Modern Pathol 17:728–731
Zuidervaart HJ (2010) The ‘true inventor’ of the telescope. A survey of 400 years of debate. In: Van Helden A et al (eds) The origins of the telescope. Amsterdam University Press, Amsterdam, p 43
Zureick AH, Burk-Rafel JB, Purkiss JA, Hortsch M (2018) The interrupted learner: how distractions during live and video lectures influence learning outcomes. Anat Sci Educ 11:366–376
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Chapman, J.A., Lee, L.M.J., Swailes, N.T. (2020). From Scope to Screen: The Evolution of Histology Education. In: Rea, P.M. (eds) Biomedical Visualisation. Advances in Experimental Medicine and Biology, vol 1320. Springer, Cham. https://doi.org/10.1007/978-3-030-47483-6_5
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