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Methodological Aspects of Lymphoscintigraphy: Bicompartmental Versus Monocompartmental Radiocolloid Administration

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Atlas of Lymphoscintigraphy and Sentinel Node Mapping

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Abstract

This chapter reviews the methodological aspects of peripheral lymphoscintigraphy. Advantages and disadvantages of intradermal versus subcutaneous radiopharmaceutical administration and subfascial injections are discussed. The protocol currently used at our site for bicompartmental peripheral lymphoscintigraphy, enabling investigation of the deep lymphatic circulation first followed by evaluation of the superficial lymphatic circulation, is described. Imaging protocols for peripheral lymphoscintigraphy as well as for intracavitary lymph effusions with the most widely employed stress tests to enhance lymphatic flow are also reviewed. Interpretation and reporting by visual qualitative analysis and by semiquantitative evaluation are carefully reported and discussed. The basic concepts of imaging lymphatic circulation with PET/CT, PET/MR, CT, and indocyanine green are also presented and discussed.

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Authors and Affiliations

  1. Department of Biomedical Sciences, Humanitas University, Milan, Italy

    Martina Sollini

  2. Regional Center of Nuclear Medicine, Department of Translational Research and Advanced Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

    Francesco Bartoli, Andrea Marciano, Roberta Zanca, Giuliano Mariani & Paola A. Erba

  3. Department of Nuclear Medicine, Medical Research, Rome, Italy

    Giovanni D’Errico

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  5. Giovanni D’Errico
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  6. Giuliano Mariani
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  7. Paola A. Erba
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Correspondence to Paola A. Erba .

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Editors and Affiliations

  1. Regional Center of Nuclear Medicine Department of Translational Research and Advanced Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

    Giuliano Mariani

  2. Nuclear Medicine Department, Hospital Clinic Barcelona, Barcelona, Catalonia, Spain

    Sergi Vidal-Sicart

  3. Department of Radiology Section of Nuclear Medicine and Interventional Molecular Imaging Laboratory, Leiden University Medical Center, Leiden, The Netherlands

    Renato A. Valdés Olmos

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Sollini, M. et al. (2020). Methodological Aspects of Lymphoscintigraphy: Bicompartmental Versus Monocompartmental Radiocolloid Administration. In: Mariani, G., Vidal-Sicart, S., Valdés Olmos, R. (eds) Atlas of Lymphoscintigraphy and Sentinel Node Mapping. Springer, Cham. https://doi.org/10.1007/978-3-030-45296-4_4

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  • DOI: https://doi.org/10.1007/978-3-030-45296-4_4

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