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Polysaccharides of Microbial Origin pp 1–34Cite as

Bacterial Polysaccharides Versatile Medical Uses

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Abstract

During the last years, a lot of research results have been published concerning to new approaches to extend the use of microbial and particularly bacterial polysaccharides, in pharmaceutical and medical practice. Most of them were focused on new developments of already well-known, authorized on the health market, commercial polysaccharides (dextran, hyaluronic acid, xanthan, gellan, bacterial cellulose, levan), but regarding new derivatives and associations, having in view the progress in nanomedicine and preparative techniques. An overview of the state of the art in the main directions of research, starting from their present recognized applications, is presented, trying to notice challenges and perspectives. Efficient targeting and for controlled release drug carriers, especially of antitumor hydrophobic, low water soluble drugs, topical therapeutic agents, especially for wound healing, suitable scaffolds in tissue engineering, surgery, have been given major attention. Attempts of new producing strains and products were also mentioned. Among the challenges, the necessity of ensuring a competitive ratio price/performance and full completion of the steps, especially in nonclinical (preclinical) development of an innovative/improved medicine or medical device, are highlighted.

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  1. National Institute for Chemical Pharmaceutical Research and Development, Bucharest, Romania

    Misu Moscovici & Cristina Balas

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  1. Misu Moscovici
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  2. Cristina Balas
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  1. 3Bs Research Grp, Zona Indus da Gan, University of Minho, BARCO GMR, Portugal

    Joaquim Oliveira

  2. 3Bs Research Grp, Zona Indus da Gan, University of Minho, BARCO GMR, Portugal

    Hajer Radhouani

  3. 3Bs Research Grp, Zona Indus da Gan, University of Minho, BARCO GMR, Portugal

    Rui L. Reis

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Moscovici, M., Balas, C. (2021). Bacterial Polysaccharides Versatile Medical Uses. In: Oliveira, J., Radhouani, H., Reis, R.L. (eds) Polysaccharides of Microbial Origin. Springer, Cham. https://doi.org/10.1007/978-3-030-35734-4_48-1

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  • DOI: https://doi.org/10.1007/978-3-030-35734-4_48-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-35734-4

  • Online ISBN: 978-3-030-35734-4

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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