Abstract
This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.
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Bricks, B.: Low cost effective modular osseointegration prosthetics for large bone loss surgical procedures (EP/R01513/1). Funded by Engineering and Physical Sciences Research Council (EPSRC) of the UK, the Global Challenges Research Fund (GCRF) under the call Diagnostics, prosthetics and orthotics to tackle health challenges in developing countries
Acknowledgement
This project has been supported by the University of Manchester and the Engineering and Physical Sciences Research Council (EPSRC) of the UK, the Global Challenges Research Fund (CRF), grant number EP/R01513/1.
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Daskalakis, E. et al. (2020). Composite Scaffolds for Large Bone Defects. In: Almeida, H., Vasco, J. (eds) Progress in Digital and Physical Manufacturing. ProDPM 2019. Lecture Notes in Mechanical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-030-29041-2_31
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DOI: https://doi.org/10.1007/978-3-030-29041-2_31
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