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Nutrition and Cardiovascular Disease

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Abstract

Cardiovascular diseases (CVDs) are a leading cause of mortality internationally, accounting for approximately one third of all deaths. Multiple risk factors are attributed to causing CVDs. An unhealthy dietary pattern, characterized by regular choices of potentially harmful foods and beverages, is currently recognized as a leading contributor to poor cardiovascular health. Poor diet was the attributed cause of CVD death for approximately 10 million people worldwide in 2017, in part as a result of its effects on other major risk factors. Healthy dietary practices, therefore, reduce the risk of CVDs, with potential implications in all-cause and CVD mortality. Herein we summarize the evidence of associations between different dietary patterns and CVD risk and discuss some of the most challenging issues about diet-disease relationship that could be considered for further research.

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References

  1. GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392:1736–88. https://doi.org/10.1016/S0140-6736(18)32203-7.

    Article  Google Scholar 

  2. Buttar HS, Li T, Ravi N. Prevention of cardiovascular diseases: role of exercise, dietary interventions, obesity and smoking cessation. Exp Clin Cardiol. 2005;10:229–49.

    CAS  PubMed  PubMed Central  Google Scholar 

  3. Myers J. Exercise and cardiovascular health. Circulation. 2003;107:e2–5. https://doi.org/10.1161/01.CIR.0000048890.59383.8D.

    Article  PubMed  Google Scholar 

  4. Stampfer MJ, Hu FB, Manson JE, Rimm EB, Willett WC. Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med. 2000;343:16–22. https://doi.org/10.1056/NEJM200007063430103.

    Article  CAS  PubMed  Google Scholar 

  5. Barbaresko J, Rienks J, Nöthlings U. Lifestyle indices and cardiovascular disease risk: a meta-analysis. Am J Prev Med. 2018;155:555–64. https://doi.org/10.1016/j.amepre.2018.04.046.

    Article  Google Scholar 

  6. Tapsell LC, Neale EP, Probst Y. Dietary patterns and cardiovascular disease: insights and challenges for considering food groups and nutrient sources. Curr Atheroscler Rep. 2019;21:9. https://doi.org/10.1007/s11883-019-0770-1.

    Article  PubMed  PubMed Central  Google Scholar 

  7. GBD 2017 Diet Collaborators. Health effects of dietary risks in 195 Countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2019;393:1958–72. https://doi.org/10.1016/S0140-6736(19)30041-8.

    Article  Google Scholar 

  8. Micha R, Kalantarian S, Wirojratana P, Byers T, Denaei G, Elmadfa I, et al. Estimating the global and regional burden of suboptimal nutrition on chronic disease: methods and inputs to the analysis. Eur J Clin Nutr. 2012;66:119–29. https://doi.org/10.1038/ejcn.2011.147.

    Article  CAS  PubMed  Google Scholar 

  9. Imamura F, Micha R, Khatibzadeh S, Fahimi S, Shi P, Powles J, et al. Dietary quality among men and women in 187 countries in 1990 and 2010: a systematic assessment. Lancet Glob Health. 2015;3:e132–42. https://doi.org/10.1016/S2214-109X(14)70381-X.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Gofman JW, Lindgren F. The role of lipids and lipoproteins in atherosclerosis. Science. 1950;111:166–71. https://doi.org/10.1126/science.111.2877.166.

    Article  CAS  PubMed  Google Scholar 

  11. Keys A, Mickelsen O, Miller EV, Chapman CB. The relation in man between cholesterol levels in the diet and in the blood. Science. 1950;112:79–81. https://doi.org/10.1126/science.112.2899.79.

    Article  CAS  PubMed  Google Scholar 

  12. Keys A. Coronary heart disease in seven countries. Circulation. 1970;41:1–211.

    Article  Google Scholar 

  13. Keys A, Menotti A, Karvonen MJ, Aravanis C, Blackburn H, Buzina R, et al. The diet and 15-year death rate in the seven countries study. Am J Epidemiol. 1986;124:903–15. https://doi.org/10.1093/oxfordjournals.aje.a114480.

    Article  CAS  PubMed  Google Scholar 

  14. Eckel RH, Jakicic JM, Ard JD, De Jesus JM, Miller NH, Hubbard VS, et al. 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014;63:2960–84. https://doi.org/10.1161/01.cir.0000437740.48606.d1.

    Article  PubMed  Google Scholar 

  15. Cordain L, Boyd Eaton S, Sebastian A, Mann N, Lindeberg S, Watkins BA, et al. Origins and evolution of the Western diet: health implications for the 21st century. Am J Clin Nutr. 2005;81:341–54. https://doi.org/10.1093/ajcn.81.2.341.

    Article  CAS  PubMed  Google Scholar 

  16. National Health and Medical Research Council. Australian dietary guidelines. Canberra: National Health and Medical Research Council; 2013.

    Google Scholar 

  17. Government of Canada. Eating well with Canada’s food guide. Ontario: Health Canada; 2011.

    Google Scholar 

  18. Public Health England. Eatwell Guide Public Health England in association with the Welsh government, Food Standards Scotland and the Food Standards Agency in Northern Ireland. 2016.

    Google Scholar 

  19. Fardet A, Rock E. Toward a new philosophy of preventive nutrition: from a reductionist to a holistic paradigm to improve nutritional recommendations. Adv Nutr. 2014;5:430–46. https://doi.org/10.3945/an.114.006122.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Nettleton JA, Brouwer IA, Geleijnse JM, Hornstra G. Saturated fat consumption and risk of coronary heart disease and ischemic stroke: a science update. Ann Nutr Metab. 2017;70:26–33. https://doi.org/10.1159/000455681.

    Article  CAS  PubMed  Google Scholar 

  21. Van’t Riet J, Sijtsema SJ, Dagevos H, De Bruijn GJ. The importance of habits in eating behaviour. An overview and recommendations for future research. Appetite. 2011;57:585–96. https://doi.org/10.1016/j.appet.2011.07.010.

    Article  Google Scholar 

  22. Brug J. Determinants of healthy eating: motivation, abilities and environmental opportunities. Fam Pract. 2008;25:i50–5. https://doi.org/10.1093/fampra/cmn063.

    Article  PubMed  Google Scholar 

  23. Charreire H, Kesse-Guyot E, Bertrai S, Simon C, Chaix B, Weber C, Touvier M, et al. Associations between dietary patterns, physical activity (leisure-time and occupational) and television viewing in middle-aged French adults. Br J Nutr. 2011;105:902–10. https://doi.org/10.1017/S000711451000440X.

    Article  CAS  PubMed  Google Scholar 

  24. Fawehinmi TO, Ilomäki J, Voutilainen S, Kauhanen J. Alcohol consumption and dietary patterns: the FinDrink study. PLoS One. 2012;7:e38607. https://doi.org/10.1371/journal.pone.0038607.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Grandner MA, Jackson N, Gerstner JR, Knutson KL. Dietary nutrients associated with short and long sleep duration: data from a nationally representative sample. Appetite. 2013;64:71–80. https://doi.org/10.1016/j.appet.2013.01.004.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Nugent R. Bringing agriculture to the table. Chicago: Chicago Council on Global Affairs; 2011.

    Google Scholar 

  27. Mozaffarian D. Dietary policy priorities for cardiovascular disease, diabetes, and obesity: a comprehensive review. Circulation. 2016;133:187–225. https://doi.org/10.1161/CIRCULATIONAHA.115.018585.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  28. Trichopoulou A, Costacou T, Bamia C, Trichopoulos D. Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med. 2003a;348:2599–608. https://doi.org/10.1056/NEJMoa025039.

    Article  PubMed  Google Scholar 

  29. Fung TT, Rexrode KM, Mantzoros CS, Manson JE, Willett WC, Hu FB. Mediterranean diet and incidence of and mortality from coronary heart disease and stroke in women. Circulation. 2009;119:1093–100. https://doi.org/10.1161/CIRCULATIONAHA.108.816736.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Tapsell LC, Neale EP, Satija A, Hu FB. Foods, nutrients, and dietary patterns: interconnections and implications for dietary guidelines. Adv Nutr. 2016;7:445–54. https://doi.org/10.3945/an.115.011718.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  31. Dinu M, Pagliai G, Angelino D, Rosi A, Dall’Asta M, Bresciani L, et al. Effects of popular diets on anthropometric and cardiometabolic parameters: an umbrella review of meta-analyses of randomized controlled trials. Adv Nutr. 2020. https://doi.org/10.1093/advances/nmaa006.

  32. Dong T, Guo M, Zhang P, Sun G, Chen B. The effects of low-carbohydrate diets on cardiovascular risk factors: a meta-analysis. PLoS One. 2020;15:e0225348. https://doi.org/10.1371/journal.pone.0225348.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  33. Hite AH, Berkowitz VG, Berkowitz K. Low-carbohydrate diet review: shifting the paradigm. Nutr Clin Pract. 2011;26:300–8. https://doi.org/10.1177/0884533611405791.

    Article  PubMed  Google Scholar 

  34. Giugliano D, Maiorino MI, Bellastella G, Esposito K. More sugar? No, thank you! The elusive nature of low carbohydrate diets. Endocrine. 2018;61:383–7. https://doi.org/10.1007/s12020-018-1580-x.

    Article  CAS  PubMed  Google Scholar 

  35. Nordmann AJ, Nordmann A, Briel M, Keller U, Yancy WS Jr, Brehm BJ, et al. Effects of low carbohydrate vs. low-fat diets on weight loss and cardiovascular risk factors: a meta-analysis of randomized controlled trials. Arch Intern Med. 2006;166:285–93. https://doi.org/10.1001/archinte.166.3.285.

    Article  CAS  PubMed  Google Scholar 

  36. Santos FL, Esteves SS, da Costa PA, Yancy WS Jr, Nunes JP. Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors. Obes Rev. 2012;13:1048–66. https://doi.org/10.1111/j.1467-789X.2012.01021.x.

    Article  CAS  PubMed  Google Scholar 

  37. Trichopoulou A, Psaltopoulou T, Orfanos P, Hsieh CC, Trichopoulos D. Low-carbohydrate- high-protein diet and long-term survival in a general population cohort. Eur J Clin Nutr. 2007;61:575–81. https://doi.org/10.1038/sj.ejcn.1602557.

    Article  CAS  PubMed  Google Scholar 

  38. Pallazola VA, Davis DM, Whelton SP, Cardoso R, Latina JM, Michos ED, et al. A clinician’s guide to healthy eating for cardiovascular disease prevention. Mayo Clin Proc Innov Qual Outcomes. 2019;3:251–67. https://doi.org/10.1016/j.mayocpiqo.2019.05.001.

    Article  PubMed  PubMed Central  Google Scholar 

  39. Kirkpatrick CF, Bolick JP, Kris-Etherton PM, Sikand G, Aspry KE, Soffer DE, et al. Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low- carbohydrate (including ketogenic) diets for the management of body weight and other cardiometabolic risk factors: a scientific statement from the National Lipid Association Nutrition and Lifestyle Task Force. J Clin Lipidol. 2019;13:689–711. https://doi.org/10.1016/j.jacl.2019.08.003.

    Article  PubMed  Google Scholar 

  40. Sumithran P, Prendergast L, Delbridge E, et al. Ketosis and appetite-mediating nutrients and hormones after weight loss. Eur J Clin Nutr. 2013;67:759–64. https://doi.org/10.1038/ejcn.2013.90.

    Article  CAS  PubMed  Google Scholar 

  41. Castellana M, Conte E, Cignarelli A, Perrini S, Giustina A, Giovanella L, et al. Efficacy and safety of very low-calorie ketogenic diet (VLCKD) in patients with overweight and obesity: a systematic review and meta-analysis. Rev Endocr Metab Disord. 2019. https://doi.org/10.1007/s11154-019-09514-y.

  42. Trimboli P, Castellana M, Bellido D, Casanueva FF. Confusion in the nomenclature of ketogenic diets blurs evidence. Rev Endocr Metabol Disord. 2020. https://doi.org/10.1007/s11154-020-09546-9.

  43. Lichtenstein AH, Appel LJ, Brands M, Carnethon M, Daniels S, Franch HA, et al. Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation. 2006;114:82–96. https://doi.org/10.1161/CIRCULATIONAHA.106.176158.

    Article  PubMed  Google Scholar 

  44. Howard BV, Van Horn L, Hsia J, Manson JA, Stefanick ML, Wassertheil-Smoller S, et al. Low- fat dietary pattern and risk of cardiovascular disease: the Women’s Health Initiative randomized controlled dietary modification trial. JAMA. 2006;295:655–66. https://doi.org/10.1001/jama.295.6.655.

    Article  CAS  PubMed  Google Scholar 

  45. Prentice RL, Aragaki AK, Van Horn L, Thomson CA, Beresford SA, Robinson J, et al. Low-fat dietary pattern and cardiovascular disease: results from the Women’s Health Initiative randomized controlled trial. Am J Clin Nutr. 2017;106:35–43. https://doi.org/10.3945/ajcn.117.153270.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  46. Bazzano LA, Hu T, Reynolds K, Yao L, Bunol C, Liu Y, et al. Effects of low-carbohydrate and low-fat diets: a randomized trial. Ann Intern Med. 2014;161:309–18. https://doi.org/10.7326/M14-0180.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Hooper L, Summerbell CD, Thompson R, Sills D, Roberts FG, Moore H, et al. Reduced or modified dietary fat for preventing cardiovascular disease. Cochrane Database Syst Rev. 2011;7:CD002137. https://doi.org/10.1002/14651858.CD002137.pub2.

    Article  Google Scholar 

  48. Tobias DK, Chen M, Manson JE, Ludwig D, Willett W, Hu FB. Effect of low-fat diet interventions versus other diet interventions on long-term weight change in adults: a systematic review and meta-analysis. Lancet Diabetes Endocrinol. 2015;3:968–79. https://doi.org/10.1016/S2213-8587(15)00367-8.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Dong YJ, Zhang ZL, Wang PY, Qin LQ. Effects of high-protein diets on body weight, glycaemic control, blood lipids and blood pressure in type 2 diabetes: meta-analysis of randomised controlled trials. Br J Nutr. 2013;110:781–9. https://doi.org/10.1017/S0007114513002055.

    Article  CAS  PubMed  Google Scholar 

  50. Schwingshackl L, Hoffmann G. Long-term effects of low-fat diets either low or high in protein on cardiovascular and metabolic risk factors: a systematic review and meta-analysis. Nutr J. 2013;12:48. https://doi.org/10.1186/1475-2891-12-48.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  51. Appel LJ. The effects of protein intake on blood pressure and cardiovascular disease. Curr Opin Lipidol. 2003;14:55–9. https://doi.org/10.1097/00041433-200302000-00010.

    Article  CAS  PubMed  Google Scholar 

  52. Baba NH, Sawaya S, Torbay N, Habbal Z, Azar S, Hashim SA. High protein vs high carbohydrate hypoenergetic diet for the treatment of obese hyperinsulinemic subjects. Int J Obes Relat Metab Disord. 1999;23:1202–6. https://doi.org/10.1038/sj.ijo.0801064.

    Article  CAS  PubMed  Google Scholar 

  53. Worthington BS, Taylor LE. Balanced low-calorie vs. high-protein-low-carbohydrate reducing diets: I. Weight loss, nutrient intake, and subjective evaluation. J Am Diet Assoc. 1974;64:47–51.

    CAS  PubMed  Google Scholar 

  54. Layman DK, Boileau RA, Erickson DJ, Painter JE, Shiue H, Sather C, et al. A reduced ratio of dietary carbohydrate to protein improves body composition and blood lipid profiles during weight loss in adult women. J Nutr. 2003;133:411–7. https://doi.org/10.1093/jn/133.2.411.

    Article  CAS  PubMed  Google Scholar 

  55. Whitehead JM, McNeill G, Smith JS. The effect of protein intake on 24-h energy expenditure during energy restriction. Int J Obes Relat Metab Disord. 1996;20:727–32. https://doi.org/10.1093/jn/133.2.411.

    Article  CAS  PubMed  Google Scholar 

  56. Hu FB. Protein, body weight, and cardiovascular health. Am J Clin Nutr. 82:242S–7S. https://doi.org/10.1093/ajcn/82.1.242S.

  57. Lagiou P, Sandin S, Lof M, Trichopoulos D, Adami HO, Weiderpass E. Low carbohydrate-high protein diet and incidence of cardiovascular diseases in Swedish women: prospective cohort study. BMJ. 2012;344:e4026. https://doi.org/10.1136/bmj.e4026.

    Article  PubMed  PubMed Central  Google Scholar 

  58. Martínez-González MA, Gea A, Ruiz-Canela M. The Mediterranean diet and cardiovascular health. Circ Res. 2019;124:779–98. https://doi.org/10.1161/CIRCRESAHA.118.313348.

    Article  CAS  PubMed  Google Scholar 

  59. Schwingshackl L, Hoffmann G. Mediterranean dietary pattern, inflammation and endothelial function: a systematic review and meta-analysis of intervention trials. Nutr Metab Cardiovasc Dis. 2014;24:929–39. https://doi.org/10.1016/j.numecd.2014.03.003.

    Article  CAS  PubMed  Google Scholar 

  60. Guo X, Tresserra-Rimbau A, Estruch R, Martínez-González MA, Medina-Remón A, Castañer O, et al. Effects of polyphenol, measured by a biomarker of total polyphenols in urine, on cardiovascular risk factors after a long-term follow-up in the PREDIMED study. Oxidative Med Cell Longev. 2016;2016:2572606. https://doi.org/10.1155/2016/2572606.

    Article  CAS  Google Scholar 

  61. Lopez-Garcia E, Rodriguez-Artalejo F, Li TY, Fung TT, Li S, Willett WC, et al. The Mediterranean-style dietary pattern and mortality among men and women with cardiovascular disease. Am J Clin Nutr. 2014;99:172–80. https://doi.org/10.3945/ajcn.113.068106.

    Article  CAS  PubMed  Google Scholar 

  62. Becerra-Tomás N, Blanco Mejía S, Viguiliouk E, Khan T, Kendall CWC, Kahleova H, et al. Mediterranean diet, cardiovascular disease and mortality in diabetes: a systematic review and meta-analysis of prospective cohort studies and randomized clinical trials. Crit Rev Food Sci Nutr. 2019; 1–21. https://doi.org/10.1080/10408398.2019.1565281.

  63. Grosso G, Marventano S, Yang J, Micek A, Pajak A, Scalfi L, et al. A comprehensive meta-analysis on evidence of Mediterranean diet and cardiovascular disease: are individual components equal? Crit Rev Food Sci Nutr. 2017;57:3218–32. https://doi.org/10.1080/10408398.2015.1107021.

    Article  PubMed  Google Scholar 

  64. Soltani S, Chitsazi MJ, Salehi-Abargouei A. The effect of dietary approaches to stop hypertension (DASH) on serum inflammatory markers: a systematic review and meta-analysis of randomized trials. Clin Nutr. 2018;37:542–50. https://doi.org/10.1016/j.clnu.2017.02.018.

    Article  CAS  PubMed  Google Scholar 

  65. Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, et al. A clinical trial of the effects of dietary patterns on blood pressure: dash collaborative research group. N Engl J Med. 1997;336:1117–24. https://doi.org/10.1056/NEJM199704173361601.

    Article  CAS  PubMed  Google Scholar 

  66. Sacks FM, Svetkey LP, Vollmer WM, Appel LJ, Bray GA, Harsha D, et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. N Engl J Med. 2001;344:3–10. https://doi.org/10.1056/NEJM200101043440101.

    Article  CAS  PubMed  Google Scholar 

  67. Levitan EB, Lewis CE, Tinker LF, Eaton CB, Ahmed A, Manson JE, et al. Mediterranean and DASH diet scores and mortality in women with heart failure: the Women’s Health Initiative. Circ Heart Fail. 2013;6:1116–23. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000495.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  68. Jones NRV, Forouhi NG, Khaw KT, Wareham NJ, Monsivais P. Accordance to the dietary approaches to stop hypertension diet pattern and cardiovascular disease in a British, population-based cohort. Eur J Epidemiol. 2018;33:235–44. https://doi.org/10.1007/s10654-017-0354-8.

    Article  PubMed  PubMed Central  Google Scholar 

  69. Salehi-Abargouei A, Maghsoudi Z, Shirani F, Azadbakht L. Effects of dietary approaches to stop hypertension (DASH)-style diet on fatal or nonfatal cardiovascular diseases – incidence: a systematic review and meta-analysis on observational prospective studies. Nutrition. 2013;29:611–8. https://doi.org/10.1016/j.nut.2012.12.018.

    Article  PubMed  Google Scholar 

  70. Ravera A, Carubelli V, Sciatti E, Bonadei I, Gorga E, Cani D, et al. Nutrition and cardiovascular disease: finding the perfect recipe for cardiovascular health. Nutrients. 2016;8:363. https://doi.org/10.3390/nu8060363.

    Article  PubMed Central  Google Scholar 

  71. Adamsson V, Reumark A, Cederholm T, Vessby B, Risérus U, Johansson G. What is a healthy Nordic diet? Foods and nutrients in the NORDIET study. Food Nutr Res 2012; 56. https://doi.org/10.3402/fnr.v56i0.18189.

  72. Adamsson V, Reumark A, Fredriksson IB, Hammarstrom E, Vessby B, Johansson G, et al. Effects of a healthy Nordic diet on cardiovascular risk factors in hypercholesterolaemic subjects: a randomized controlled trial (NORDIET). J Intern Med. 2011;269:150–9. https://doi.org/10.1111/j.1365-2796.2010.02290.x.

    Article  CAS  PubMed  Google Scholar 

  73. Olsen A, Egeberg R, Halkjaer J, Christensen J, Overvad K, Tjonneland A. Healthy aspects of the Nordic diet are related to lower total mortality. J Nutr. 2011;141:639–44. https://doi.org/10.3945/jn.110.131375.

    Article  CAS  PubMed  Google Scholar 

  74. Roswall N, Sandin S, Lof M, Skeie G, Olsen A, Adami HO, et al. Adherence to the healthy Nordic food index and total and cause-specific mortality among Swedish women. Eur J Epidemiol. 2015;30:509–17. https://doi.org/10.1007/s10654-015-0021-x.

    Article  PubMed  Google Scholar 

  75. Puaschitz NG, Assmus J, Strand E, Karlsson T, Vinknes KJ, Lysne V, et al. Adherence to the healthy Nordic Food Index and the incidence of acute myocardial infarction and mortality among patients with stable angina pectoris. J Hum Nutr Diet. 2019;32:86–97. https://doi.org/10.1111/jhn.12592.

    Article  CAS  PubMed  Google Scholar 

  76. Wang F, Zheng J, Yang B, Jiang J, Fu Y, Li D. Effects of vegetarian diets on blood lipids: a systematic review and meta-analysis of randomized controlled trials. J Am Heart Assoc. 2015;4:e002408. https://doi.org/10.1161/JAHA.115.002408.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  77. Dinu M, Abbate R, Gensini GF, Casini A, Sofi F. Vegetarian, vegan diets and multiple health outcomes: a systematic review with meta-analysis of observational studies. Crit Rev Food Sci Nutr. 2017;57:3640–9. https://doi.org/10.1080/10408398.2016.1138447.

    Article  PubMed  Google Scholar 

  78. Key TJ, Fraser GE, Thorogood M, et al. Mortality in vegetarians and nonvegetarians: Detailed findings from a collaborative analysis of 5 prospective studies. Am J Clin Nutr. 1999;70:516S–24S. https://doi.org/10.1093/ajcn/70.3.516s.

    Article  CAS  PubMed  Google Scholar 

  79. Appleby PN, Crowe FL, Bradbury KE, Travis RC, Key TJ. Mortality in vegetarians and comparable nonvegetarians in the United Kingdom. Am J Clin Nutr. 2016;103:218–30. https://doi.org/10.3945/ajcn.115.119461.

    Article  CAS  PubMed  Google Scholar 

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Bernardes, A.G., Tagliabue, A., Ferraris, C. (2020). Nutrition and Cardiovascular Disease. In: Govoni, S., Politi, P., Vanoli, E. (eds) Brain and Heart Dynamics. Springer, Cham. https://doi.org/10.1007/978-3-030-28008-6_58

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