Abstract
When the size of the future liver remnant is regarded to be insufficient to sustain liver function in the postoperative course, techniques of portal vein occlusion such as portal vein embolization or portal vein ligation can be used to increase the residual liver volume in the context of a classical two-stage hepatectomy or “associating liver partition and portal vein ligation for staged hepatectomy” procedure.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Yang C, Rahbari NN, Mees ST, et al. Staged resection of bilobar colorectal liver metastases: surgical strategies. Langenbeck’s Arch Surg. 2015;400:633–40.
Vauthey JN, Chaoui A, Do KA, et al. Standardized measurement of the future liver remnant prior to extended liver resection: methodology and clinical associations. Surgery. 2000;127:512–9.
Truant S, Oberlin O, Sergent G, et al. Remnant liver volume to body weight ratio ≥ 0.5%: a new cut-off to estimate postoperative risks after extended resection in noncirrhotic liver. J Am Coll Surg. 2007;204:22–33.
Guglielmi A, Ruzzenente A, Conci S, et al. How much remnant is enough in liver resection? Dig Surg. 2012;29:6–17.
Madoff DC, Abdalla EK, Gupta S, et al. Transhepatic ipsilateral right portal vein embolization extended to segment IV: improving hypertrophy and resection outcomes with spherical particles and coils. J Vasc Interv Radiol. 2005;16:215–25.
Broering DC, Hillert C, Krupski G, et al. Portal vein embolization vs. portal vein ligation for induction of hypertrophy of the future liver remnant. J Gastrointest Surg. 2002;6:905–13.
Abulkhir A, Limongelli P, Healey AJ, et al. Preoperative portal vein embolization for major liver resection: a meta-analysis. Ann Surg. 2008;247:49–57.
Lam VWT, Laurence JM, Johnston E, et al. A systematic review of two-stage hepatectomy in patients with initially unresectable colorectal liver metastases. HPB (Oxford). 2013;15:483–91.
Giuliante F, Ardito F, Ferrero A, et al. Tumor progression during preoperative chemotherapy predicts failure to complete 2-stage hepatectomy for colorectal liver metastases: results of an Italian multicenter analysis of 130 patients. J Am Coll Surg. 2014;219:285–94.
Schnitzbauer AA, Lang SA, Goessmann H, et al. Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings. Ann Surg. 2012;255:405–14.
Alvarez FA, Ardiles V, de Santibañes M, et al. Associating liver partition and portal vein ligation for staged hepatectomy offers high oncological feasibility with adequate patient safety: a prospective study at a single center. Ann Surg. 2015;261:723–32.
de Santibañes E, Alvarez FA, Ardiles V, et al. Inverting the ALPPS paradigm by minimizing first stage impact: the mini-ALPPS technique. Langenbeck's Arch Surg. 2016;401:557–63.
Pekolj J, Alvarez FA, Biagiola D, et al. Totally laparoscopic mini-ALPPS using a novel approach of laparoscopic-assisted transmesenteric portal vein embolization. J Laparoendosc Adv Surg Tech A. 2018;28:1229–33.
Schadde E, Raptis DA, Schnitzbauer AA, et al. Prediction of mortality after ALPPS stage-1: an analysis of 320 patients from the International ALPPS Registry. Ann Surg. 2015;262:780–5; discussion 785–6.
Serenari M, Zanello M, Schadde E, et al. Importance of primary indication and liver function between stages: Results of a multicenter Italian audit of ALPPS 2012-2014. HPB (Oxford). 2016;18:419–27.
Olthof PB, Tomassini F, Huespe PE, et al. Hepatobiliary scintigraphy to evaluate liver function in associating liver partition and portal vein ligation for staged hepatectomy: liver volume overestimates liver function. Surgery. 2017;162:775–83.
Serenari M, Collaud C, Alvarez FA, et al. Interstage assessment of remnant liver function in ALPPS using hepatobiliary scintigraphy: prediction of posthepatectomy liver failure and introduction of the HIBA index. Ann Surg. 2017;267:1141–7.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Serenari, M., Jovine, E. (2020). Regeneration Techniques: TSH and ALPPS. In: Cillo, U., De Carlis, L. (eds) Liver Transplantation and Hepatobiliary Surgery. Updates in Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-19762-9_14
Download citation
DOI: https://doi.org/10.1007/978-3-030-19762-9_14
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-19761-2
Online ISBN: 978-3-030-19762-9
eBook Packages: MedicineMedicine (R0)