Abstract
During exercise, CO2 production by the muscles increases dramatically. The CO2 is transported from the muscles to the lungs via the bloodstream. Two mechanisms permit the efficient transport of the increased quantities of CO2: (1) cardiac output may increase more than fivefold during exercise; and (2) venous CO2 content rises during exercise. Unlike oxygen, CO2 is very soluble in blood. In the physiologic range, the CO2 content is approximately proportional to the partial pressure of CO2 (pCO2). Mixed venous pCO2 levels may increase from 42–45 mm Hg at rest to as much as 60 mm Hg (or more) at peak exercise.
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References
Jones NL. Clinical exercise testing. 4th ed. Philadelphia: W. B. Saunders; 1997.
Whipp BJ, Ward SA, Wasserman K. Ventilatory responses to exercise and their control in man. Am Rev Respir Dis. 1984;129(2 Pt 2):S17–20.
Wasserman K, Cox TA, Sietsema KE. Ventilatory regulation of arterial h(+) (ph) during exercise. Respir Physiol Neurobiol. 2014;190:142–8.
Sietsema KE, Cooper DM, Perloff JK, Child JS, Rosove MH, Wasserman K, et al. Control of ventilation during exercise in patients with central venous-to-systemic arterial shunts. J Appl Physiol. 1988;64(1):234–42.
Wasserman K. Determinants and detection of anaerobic threshold and consequences of exercise above it. Circulation. 1987;76(Supp VI)(6:Pt 2)):VI-29-VI-39.
Wasserman K. The Dickinson w. Richards lecture. New concepts in assessing cardiovascular function. Circulation. 1988;78(4):1060–71.
Wasserman K. The anaerobic threshold measurement to evaluate exercise performance. Am Rev Respir Dis. 1984;129(2:Pt 2):t-40.
Acknowledgment
Portions of this chapter were based upon the author’s previously published works:
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Rhodes J, Ubeda TA, Jenkins KJ. Exercise testing and training in children with congenital heart disease. Circulation. 2010;122(19):1957–67.
-
Rhodes J. Exercise testing. In: Keane JF, Lock JE, Fyler DC, editors. Nadas’ pediatric cardiology. 2nd ed. Philadelphia: Elsevier; 2006.
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Rhodes, J. (2019). CO2 Elimination (V̇CO2). In: Rhodes, J., Alexander, M., Opotowsky, A. (eds) Exercise Physiology for the Pediatric and Congenital Cardiologist. Springer, Cham. https://doi.org/10.1007/978-3-030-16818-6_4
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DOI: https://doi.org/10.1007/978-3-030-16818-6_4
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