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Essential Role of Genetics in the Advancement of Biotechnology

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Microbial Carotenoids From Fungi

Part of the book series: Methods in Molecular Biology ((MIMB,volume 898))

Abstract

Microorganisms are one of the greatest sources of metabolic and enzymatic diversity. In recent years, emerging recombinant DNA and genomic techniques have facilitated the development of new efficient expression systems, modification of biosynthetic pathways leading to new metabolites by metabolic engineering, and enhancement of catalytic properties of enzymes by directed evolution. Complete sequencing of industrially important microbial genomes is taking place very rapidly and there are already hundreds of genomes sequenced. Functional genomics and proteomics are major tools used in the search for new molecules and development of higher-producing strains.

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Authors and Affiliations

  1. Charles A. Dana Research Institute for Scientists Emeriti (R.I.S.E.), Drew University, Madison, NJ, USA

    Arnold L. Demain

  2. Neuron BioIndustrial Division, Neuron BPh S.A., Granada, Spain

    José L. Adrio

  3. Parque Tecnologico de Ciencias de la Salud, Granada, Spain

    José L. Adrio

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  1. Arnold L. Demain
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  2. José L. Adrio
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Correspondence to Arnold L. Demain .

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  1. Parque Tecnológico de León, Gadea Biopharma, Boecillo 47151, Valladolid, 24009, León, Spain

    José-Luis Barredo

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Demain, A.L., Adrio, J.L. (2012). Essential Role of Genetics in the Advancement of Biotechnology. In: Barredo, JL. (eds) Microbial Carotenoids From Fungi. Methods in Molecular Biology, vol 898. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-918-1_1

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  • DOI: https://doi.org/10.1007/978-1-61779-918-1_1

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