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Structural Biology of Programmed Cell Death

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Book cover Essentials of Apoptosis

Abstract

Structural and biochemical characterization on death receptors, Bcl-2 family proteins, caspases, IAPs, Smac/DIABLO, and other regulatory proteins has revealed significant insights into the molecular mechanisms of apoptosis. This chapter summarizes these advances and presents our current understanding of apoptosis from a structural and mechanistic perspective.

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  1. Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, NJ 08544, USA

    Yigong Shi

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    © 2009 Humana Press, a part of Springer Science+Business Media, LLC

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    Shi, Y. (2009). Structural Biology of Programmed Cell Death. In: Dong, Z., Yin, XM. (eds) Essentials of Apoptosis. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60327-381-7_4

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