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Chronic Viral Hepatitis pp 185–241Cite as

Epidemiology, Screening, and Natural History of Chronic Hepatitis B Infection

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Part of the book series: Clinical Gastroenterology ((CG))

Abstract

Key Principles

Hepatitis B virus (HBV) infection continues to be a global public health problem despite large-scale efforts to eliminate this disease through education, screening, and vaccination programs.

An estimated 400 million individuals are chronically infected with HBV which results in nearly 1 million deaths each year from decompensated cirrhosis or HCC.

A wide variability exists in the prevalence rates of HBV worldwide with sub-Saharan Africa, mainland China, and many countries of Southeast Asia being hyperendemic in HBV.

Maternal–fetal transmission of hepatitis B virus is an important problem, particularly in endemic areas such as Southeast Asia and Africa.

Immunization against HBV has been a successful experience in various countries. It is hoped that universal vaccination campaigns will eventually reduce or eliminate the impact of this disease in many parts of the world.

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We are thankful to Mrs Meena Bajaj for computer and graphic assistance.

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    Shiv K. Sarin MD & Manoj Kumar MD

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  1. Department of Hepatology, Georgetown University Hospital, Reservoir Road GUH 3800, Washington, 20007, U.S.A.

    Kirti Shetty

  2. University of Connecticut Health Center, Farmington Ave. 236, Farmington, 06030-1845, U.S.A.

    George Y. Wu

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Sarin, S.K., Kumar, M. (2009). Epidemiology, Screening, and Natural History of Chronic Hepatitis B Infection. In: Shetty, K., Wu, G. (eds) Chronic Viral Hepatitis. Clinical Gastroenterology. Humana Press. https://doi.org/10.1007/978-1-59745-565-7_7

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