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Experimental Infection of Rodent Mammals for Fungal Virulence Testing

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Host-Pathogen Interactions

Part of the book series: Methods in Molecular Biology ((MIMB,volume 470))

Abstract

Invasive fungal infections comprise a group of serious and life-threatening diseases affecting immunocompromised patients. Molecular analysis of fungal virulence involves the deletion of genes that are suspected for contributing to fungal pathogenesis. Phenotypic analysis of the generated mutants includes in vivo infection experiments in order to assign a function during fungal disease to a gene of interest.

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Author information

Authors and Affiliations

  1. Comparative Genomics Centre, Cellular Immunology Group, James Cook University, Townsville, Australia

    Anja Schweizer

  2. Institute of Medical Microbiology and Hygiene, University of Tübingen, Tübingen, Germany

    Klaus Schröppel

Authors
  1. Anja Schweizer
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  2. Klaus Schröppel
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Editor information

Editors and Affiliations

  1. Fraunhofer Institute for Interfacial Engineering and Biotechnology, Nobelstrasse 12, 70569 Stuttgart, Germany

    Steffen Rupp  & Kai Sohn  & 

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© 2009 Humana Press, a part of Springer Science+Business Media, LLC

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Schweizer, A., Schröppel, K. (2009). Experimental Infection of Rodent Mammals for Fungal Virulence Testing. In: Rupp, S., Sohn, K. (eds) Host-Pathogen Interactions. Methods in Molecular Biology, vol 470. Humana Press. https://doi.org/10.1007/978-1-59745-204-5_12

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  • DOI: https://doi.org/10.1007/978-1-59745-204-5_12

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-886-7

  • Online ISBN: 978-1-59745-204-5

  • eBook Packages: Springer Protocols

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