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Nuclear Transfer Protocols pp 319–331Cite as

Future and Applications of Cloning

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Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 348))

Abstract

The birth of viable offspring from somatic cell nuclear transfer (SCNT) in mammals caused a major re-examination of the understanding of the commitment of cells to specific tissue lineages during differentiation. The questions of whether cells undergo dedifferentiation or transdifferentiation during the development of offspring and how these changes are controlled is a source of ongoing debate that is yet to be resolved. Irrespective of the outcome of this debate, it is clear that cloning using SCNT has a place and purpose in the future of research and animal breeding. The future uses of SCNT could include the production of transgenic mice, the production of transgenic livestock and assisting with the re-establishment of endangered species. Human medicine also would benefit from future use of SCNT because it would allow the production of patient-specific embryonic stem cells.

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Author information

Authors and Affiliations

  1. Monash Immunology and Stem Cell Laboratories, Monash University, Melbourne, Victoria, Australia

    Alan O. Trounson

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  1. Alan O. Trounson
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Editor information

Editors and Affiliations

  1. Centre for Reproduction and Development Monash Institute of Medical Research, Monash University, Melbourne, Victoria, Australia

    Paul J. Verma

  2. Monash Immunology and Stem Cell Laboratories, Monash University, Melbourne, Victoria, Australia

    Alan O. Trounson

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© 2006 Humana Press Inc.

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Trounson, A.O. (2006). Future and Applications of Cloning. In: Verma, P.J., Trounson, A.O. (eds) Nuclear Transfer Protocols. Methods in Molecular Biology™, vol 348. Humana Press. https://doi.org/10.1007/978-1-59745-154-3_22

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  • DOI: https://doi.org/10.1007/978-1-59745-154-3_22

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-280-3

  • Online ISBN: 978-1-59745-154-3

  • eBook Packages: Springer Protocols

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