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Clinical Approaches for Studying Calcium Metabolism and Its Relationship to Disease

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Calcium in Human Health

Part of the book series: Nutrition and Health ((NH))

Abstract

This chapter describes several types of clinical studies for studying the relationship of dietary calcium to health. Fractional calcium absorption studies are used to evaluate bioavailability from various sources or intrinsic calcium absorption capacity. The latter is an important risk factor for osteoporosis and possibly other disorders associated with low calcium status. The accuracy of different methods commonly used to determine fractional calcium absorption varies widely. Calcium retention measurements are useful to determine influences on bone mass in short-term studies. Randomized, controlled trials (RCTs) are the inferentially strongest approach to understanding the relationship between calcium intake and outcome measures of disease.

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Author information

Authors and Affiliations

  1. Department of Foods and Nutrition, Purdue University, West Lafayette, IN

    Connie M. Weaver PhD

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  1. Connie M. Weaver PhD
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Editors and Affiliations

  1. Department of Foods and Nutrition, Purdue University, West Lafayette, IN

    Connie M. Weaver PhD

  2. Creighton University, Omaha, NE

    Robert P. Heaney MD (John A. Creighton University Professor) (John A. Creighton University Professor)

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© 2006 Humana Press Inc., Totowa, NJ

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Weaver, C.M. (2006). Clinical Approaches for Studying Calcium Metabolism and Its Relationship to Disease. In: Weaver, C.M., Heaney, R.P. (eds) Calcium in Human Health. Nutrition and Health. Humana Press. https://doi.org/10.1007/978-1-59259-961-5_5

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