Abstract
Cancer is caused by an accumulation of genetic alterations that confer a survival advantage to the neoplastic cell. These genetic changes can affect multiple facets of cellular function, including an increased rate of cell proliferation, resistance to apoptosis, altered tissue invasiveness, production of growth and angiogenic factors, and the ability to escape immune surveillance. Different cancers reflect these features to varying degrees, depending on the nature of their cellular functions and genetic changes.
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Jameson, J.L. (1998). Oncogenes and Tumor Suppressor Genes. In: Jameson, J.L. (eds) Principles of Molecular Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-726-0_7
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DOI: https://doi.org/10.1007/978-1-59259-726-0_7
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-4757-6272-3
Online ISBN: 978-1-59259-726-0
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