Abstract
Optical coherence tomography (OCT) is an invaluable technique to perform noninvasive retinal imaging in small animal models such as mice. It provides virtual cross sections that correlate well with histomorphometric data with the advantage that multiple iterative measurements can be acquired in timeline analyses to detect dynamic changes and reduce the number of animals needed per study.
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Acknowledgments
The authors wish to acknowledge the continued support and mentoring by Drs. Zrenner, Bartz-Schmidt, Ueffing, and MacLaren.
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Ochakovski, G.A., Fischer, M.D. (2019). Phenotyping of Mouse Models with OCT. In: Weber, B.H.F., Langmann, T. (eds) Retinal Degeneration. Methods in Molecular Biology, vol 1834. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-8669-9_18
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DOI: https://doi.org/10.1007/978-1-4939-8669-9_18
Publisher Name: Humana, New York, NY
Print ISBN: 978-1-4939-8668-2
Online ISBN: 978-1-4939-8669-9
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