Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key note and implementation advice from the expert
Part of the book series: Methods in Molecular Biology (MIMB, volume 1824)
Buy it now
Buying options
Tax calculation will be finalised at checkout
Other ways to access
This is a preview of subscription content, log in via an institution to check for access.
Table of contents (27 protocols)
-
Front Matter
About this book
This volume covers several aspects of rational drug design, such as synthesis of novel bioactive drugs; development and application of new methodologies; computational methods valuable for the establishment of new approaches in drug discovery; and the effects of physical-chemical and ADMET properties of the designed potential drugs. Chapters guide readers through amyloid deposits, Saturation Transfer Difference (STD) NMR, methods on bioguided design, the importance of lipophilicity in drug design, ADMET, FRET, structural biology, and homology modeling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Rational Drug Design: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Editors and Affiliations
-
Division of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, Athens, Greece
Thomas Mavromoustakos, Tahsin F. Kellici
Bibliographic Information
Book Title: Rational Drug Design
Book Subtitle: Methods and Protocols
Editors: Thomas Mavromoustakos, Tahsin F. Kellici
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-8630-9
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018
Hardcover ISBN: 978-1-4939-8629-3Published: 24 July 2018
Softcover ISBN: 978-1-4939-9347-5Published: 10 December 2019
eBook ISBN: 978-1-4939-8630-9Published: 23 July 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 465
Number of Illustrations: 24 b/w illustrations, 124 illustrations in colour
Topics: Pharmacology/Toxicology