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Colorectal Cancer pp 299–305Cite as

Testing Cell-Based Immunotherapy for Colorectal Cancer

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1765))

Abstract

Cell-based immunotherapy for cancer is emerging as an attractive alternative to conventional small-molecule or antibody-based treatment. Due to the characteristics of cell-based therapy, validation of test materials before in vivo administration is required. Here we describe general validation steps for preclinical evaluation of cell-based immunotherapy. We also describe a xenograft model of human colorectal cancer. This model can be used for applied to preclinical evaluation of various cell-based therapy regimens for colorectal cancer treatment.

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References

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Acknowledgment

This work was supported by grants funded by the KRIBB Research Initiative Program and the Korean Government (NRF-2008-0062275).

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Authors and Affiliations

  1. Korea Research Institute of Bioscience and Biotechnology, Cheongju, Chungbuk, Republic of Korea

    Jong Soon Kang, Yeo Dae Yoon, Myeong Youl Lee & Chang Woo Lee

  2. College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea

    Suk Jong Lee & Sang-Bae Han

Authors
  1. Jong Soon Kang
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  2. Yeo Dae Yoon
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  3. Myeong Youl Lee
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  4. Chang Woo Lee
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  5. Suk Jong Lee
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  6. Sang-Bae Han
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Corresponding author

Correspondence to Sang-Bae Han .

Editor information

Editors and Affiliations

  1. Laboratory of Intestinal Physiopathology, Department of Anatomy and Cell Biology, Faculty of Medicine and Health Science, Université de Sherbrooke, Sherbrooke, Québec, Canada

    Jean-François Beaulieu

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Kang, J.S., Yoon, Y.D., Lee, M.Y., Lee, C.W., Lee, S.J., Han, SB. (2018). Testing Cell-Based Immunotherapy for Colorectal Cancer. In: Beaulieu, JF. (eds) Colorectal Cancer. Methods in Molecular Biology, vol 1765. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7765-9_19

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  • DOI: https://doi.org/10.1007/978-1-4939-7765-9_19

  • Published:

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7764-2

  • Online ISBN: 978-1-4939-7765-9

  • eBook Packages: Springer Protocols

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