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Arterial Resection in Pancreatic Cancer

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Pancreatic Cancer

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Abstract

Pancreatic cancer surgery is the only potentially curative approach for this disease and remains a formidable challenge. Better perioperative management, increased experience and advanced surgical techniques, and centralization of care have significantly reduced morbidity and mortality rates of major pancreatic resection. Together with more active and effective chemotherapeutic and radiotherapeutic regimen, this has led to an increase use of resectional procedures in borderline resectable and locally advanced unresectable tumors. Especially for the latter, arterial resection is often necessary to achieve clear margins. However, this approach is currently under debate with higher rates of complications reported. In this chapter, an overview is provided of potential indications and techniques as well as short- and long-term outcomes associated with these procedures.

Illustrations: Alan Bannister, School of Veterinary Science, University of Liverpool, L69 3GA, UK

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Author information

Authors and Affiliations

  1. Department of Surgery, The Royal Liverpool and Broadgreen University Hospitals NHS Trust, Prescot Street, Liverpool, L7 8XP, UK

    Declan F. J. Dunne, Vincent S. Yip & Paula Ghaneh

  2. Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, L69 3GA, UK

    Christopher Halloran & Paula Ghaneh

  3. Department of Visceral, Vascular and Endocrine Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40, Halle (Saale), 06120, Germany

    Jörg Kleeff

  4. Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, Heidelberg, 69120, Germany

    John P. Neoptolemos

Authors
  1. Declan F. J. Dunne
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  2. Jörg Kleeff
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  3. Vincent S. Yip
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  4. Christopher Halloran
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  5. Paula Ghaneh
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  6. John P. Neoptolemos
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Corresponding author

Correspondence to Jörg Kleeff .

Editor information

Editors and Affiliations

  1. Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany

    John P. Neoptolemos

  2. Division of Research Department of Surgery and Genomic Sciences and Precision Medicine Center (GSPMC), Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    Raul Urrutia

  3. Division of Medical Oncology, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina, USA

    James L. Abbruzzese

  4. Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany

    Markus W. Büchler

Section Editor information

  1. Duke University Medical Center, Durham, NC, USA

    James L. Abbruzzese

  2. Mayo Clinic Cancer Center, Mayo Clinic, 200 First Street SW, 55905, Rochester, MN, USA

    Raul A. Urrutia

  3. Division of Surgery and Oncology, University of Liverpool, Daulby Street, Liverpool, UK

    John Neoptolemos

  4. Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany

    Markus W. Büchler

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Dunne, D.F.J., Kleeff, J., Yip, V.S., Halloran, C., Ghaneh, P., Neoptolemos, J.P. (2018). Arterial Resection in Pancreatic Cancer. In: Neoptolemos, J., Urrutia, R., Abbruzzese, J., Büchler, M. (eds) Pancreatic Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-7193-0_72

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