Abstract
Aberrant immune synapse formation between antigen-presenting and immune effector cells is a central mediator of immune dysfunction and can be observed across several haematologic malignancies. Here, we describe the cell preparation, conjugation and immune synapse quantification of B and T cells obtained from patients with leukaemia and the adaptions required when using cells from murine models of disease.
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Lucas, F.M., Gribben, J.G. (2017). Aberrant Immunological Synapses Driven by Leukemic Antigen-Presenting Cells. In: Baldari, C., Dustin, M. (eds) The Immune Synapse. Methods in Molecular Biology, vol 1584. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6881-7_33
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DOI: https://doi.org/10.1007/978-1-4939-6881-7_33
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Publisher Name: Humana Press, New York, NY
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Online ISBN: 978-1-4939-6881-7
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