Abstract
Streptococcus pyogenes (GAS) causes many diseases including necrotizing fasciitis (NF) and myositis. Myositis destroys the muscle and NF destroys the sheath that covers the muscle (fascia). Some M-types strains M1, M3 and M5 attribute to these diseases. It is believed that the disease is probably caused by proteinases and exotoxins produced by GAS. The objective of our research is to establish an ELISA method for identifying antibodies against achromopeptidase and mutanolysin in human sera, to determine the presence of such antigens in broth and cell pellets of some GAS strains, and to assess their specificity against purified proteinases.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1997 Springer Science+Business Media New York
About this chapter
Cite this chapter
Huang, J., Diepeveen, J., Bielecki, J. (1997). Elisa for Detecting Proteinases Produced by Group A Streptococci. In: Horaud, T., Bouvet, A., Leclercq, R., de Montclos, H., Sicard, M. (eds) Streptococci and the Host. Advances in Experimental Medicine and Biology, vol 418. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1825-3_220
Download citation
DOI: https://doi.org/10.1007/978-1-4899-1825-3_220
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-1827-7
Online ISBN: 978-1-4899-1825-3
eBook Packages: Springer Book Archive