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Intermedilysin

A Cytolytic Toxin Specific for Human Cells of a Streptococcus intermedius Isolated from Human Liver Abscess

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Streptococci and the Host

Abstract

Streptococcus intermedius is one of the three distinct species classified into the Streptococcus milleri-group(SMG, S. anginosus, S. constellatus and S. intermedius) which constitutes a portion of the normal flora of the human oral cavity, as well as the upper respiratory, gastrointestinal and female urogenital tracts, and it can cause purulent infections in the mouth and internal organs. Recently, S. intermedius has been found to be associated with brain and liver abscesses3. However, the pathogenic factors of S. intermedius have not been sufficiently characterized despite their clinical importance.

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References

  1. Nagamune, H., Ohnishi, C., Katsuura, A., Fushitani, K., Whiley. R. A., Tsuji, A., and Matsuda, Y. (1996) Infect. Immun., 64, 3093–3100.

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  2. Smyth, C. J. and J. L. Duncan (1978) In Bacterial toxins and cell membranes (J. Jeljaszewicz and T. Wadstrom, eds.), pp 129–183, Academic Press, London.

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  3. Whiley, R. A., Beighton, D., Winstanley, T. G., Fraser, H. Y. and Hardie. J. M. (1992) J. Clin. Microbiol., 30, 243–244.

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© 1997 Springer Science+Business Media New York

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Nagamune, H. et al. (1997). Intermedilysin. In: Horaud, T., Bouvet, A., Leclercq, R., de Montclos, H., Sicard, M. (eds) Streptococci and the Host. Advances in Experimental Medicine and Biology, vol 418. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1825-3_182

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  • DOI: https://doi.org/10.1007/978-1-4899-1825-3_182

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1827-7

  • Online ISBN: 978-1-4899-1825-3

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